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RTN1 belongs to the family of reticulon encoding genes. Zusätzlich bieten wir Ihnen Reticulon 1 Antikörper (144) und viele weitere Produktgruppen zu diesem Protein an.
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Data suggest that reticulon 1A (RTN1A) functions not only as an endoplasmic reticulum-shaping protein but also as a protein that promotes contacts between endoplasmic reticulum and mitochondria.
Results suggest evidence of genetic association between common variants in RTN1 and end-stage kidney disease in African-Americans and European-Americans.
RTN1A is a key mediator for proteinuria-induced tubular cell toxicity and renal fibrosis.
RTN1A contributes to progression of kidney disease by inducing ER stress.
MANF (zeige MANF Proteine) is a protein that interacts with RTN1-C
RTN1-C induces PDI (zeige PADI1 Proteine) redistribution in endoplasmic reticulum vesicles, and concomitantly modulates its activity by decreasing the levels of its S-nitrosylated form.
In the present study a potential metal ion binding motif (HxE/D) at the C-terminal of the RTN1-C has been identified and its capability to bind metals investigated by UV-vis, CD, multidimensional NMR spectroscopy and biological assays.
RTN1-A and RTN1-B share N-terminal 168 amino acid region, suggesting that the 168 amino acid region might play a role in regulating the endocytic process
Data demonstrate that reticulon 1 interacts specifically with spastin (zeige SPAST Proteine).
analyzed the endoplasmic reticulum (ER) localization signal of human RTN1-A. Mutant proteins lacking the first (39 residues) or second (36 residues) hydrophobic segment showed ER localization
reticulon-1 is responsible for reduced chemotaxis of macrophages differentiated from the one bone marrow of ultraviolet-irradiated and ultraviolet-chimeric mice
XRTN1-A is expressed in early neural precursors and differentiating neuronal populations, including the trigeminal placode, olfactory placode, lateral line placode, and otic vesicle.
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants.
, neuroendocrine-specific protein
, reticulon 1 b
, reticulon 1-A
, reticulon 1, like