Recombination Activating Gene 1 (RAG1) ELISA Kits

The protein encoded by RAG1 is involved in activation of immunoglobulin V-D-J recombination. Zusätzlich bieten wir Ihnen RAG1 Antikörper (42) und RAG1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
RAG1 84600  
RAG1 5896 P15918
RAG1 19373 P15919
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Top RAG1 ELISA Kits auf antikoerper-online.de

Showing 10 out of 25 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Kaninchen 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Maus 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Ratte 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Human 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Huhn 0.469 pg/mL 0.781-50 pg/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Schwein 9.375 pg/mL 15.625-1000 pg/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Human 0.098 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$713.90
Details
Meerschweinchen 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Affe 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Hund 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details

Weitere ELISA Kits für RAG1 Interaktionspartner

Pig (Porcine) Recombination Activating Gene 1 (RAG1) Interaktionspartner

  1. Results confirm that Rag-1 is necessary for the generation of lymphocytes in pigs, and Rag-1-deficient piglets exhibit a T and B cell deficient severe combined immune deficiency(T-B-SCID (zeige PRKDC ELISA Kits)) phenotype similar to that of rodents and humans.

  2. Piglets with biallelic mutations in either RAG1 or RAG2 (zeige RAG2 ELISA Kits) exhibit hypoplasia of immune organs, fail to perform V(D)J rearrangement, and lose mature B and T cells.

Human Recombination Activating Gene 1 (RAG1) Interaktionspartner

  1. The show that DNA damage caused by RAG1 activity in pre-B cells was able to downmodulate RAG1 expression and activity, confirming the existence of a negative feedback regulatory mechanism.

  2. Our findings suggest that mutations in RAG1, specifically the p.R474C variant, can be associated with relatively mild clinical symptoms or delayed occurrence of T cell and B cell deficiencies but may predispose to progressive multifocal leukoencephalopathy.

  3. This study compares T-cell development of patients with RAG1-dependent immune deficiencies, and elucidates important differences that help to explain the wide range of immunologic phenotypes that result from different mutations within the same gene of various patients.

  4. Agammaglobulinemia associated to nasal polyposis due to a hypomorphic RAG1 mutation

  5. mutation c.256_257delAA in RAG1 gene seems to occur quite frequently in the Polish patients with severe combined immunodeficiency (zeige PRKDC ELISA Kits) and may result in classical OS as well as in severe combined immunodeficiency (zeige PRKDC ELISA Kits) without clinical and laboratory features of OS when occurred in homozygous state

  6. study reported 4 patients with RAG1 deficiency: classic severe combined immune deficiency (SCID (zeige PRKDC ELISA Kits)) was seen in 2 patients, Omenn syndrome was observed in 1 patient and atypical SCID (zeige PRKDC ELISA Kits) was seen in one patient

  7. Study reports that RAG1 associates with chromatin at thousands of active promoters and enhancers in the genome of developing lymphocytes. The mouse and human genomes appear to have responded by reducing the abundance of "cryptic" recombination signals near RAG1 binding sites.

  8. These findings provide insight into the role of this poorly understood region of Rag1 and support the role of Rag1 in a post-cleavage stage of recombination

  9. Expression of recombinase RAG-1 in diabetic patients was detected primarily in alphabetaTCR+CD40 (zeige CD40 ELISA Kits)+ lymphocytes.

  10. Bidirectional activity of the NWC promoter is responsible for RAG-2 (zeige RAG2 ELISA Kits) transcription in non-lymphoid cells [NWC]

Mouse (Murine) Recombination Activating Gene 1 (RAG1) Interaktionspartner

  1. This study demonstrated that the lymphocyte-deficient Rag1 animals demonstrated a significantly lower rate of aneurysm formation and rupture.

  2. This work provides important mechanistic insight into how spatiotemporal expression of the Rag genes is tightly controlled during B lymphocyte (zeige AKAP17A ELISA Kits) development to prevent mistimed dsDNA breaks and their deleterious consequences.

  3. a novel RAG1/2-mediated insertion pathway distinct from DNA transposition and trans-V(D)J recombination that destabilizes the genome and shares features with reported oncogenic DNA insertions.

  4. loss of the BH3-only (zeige BBC3 ELISA Kits) protein BIM (zeige BCL2L11 ELISA Kits) accelerated lymphoma development in p53 (zeige TP53 ELISA Kits)-deficient mice. This process was negated by concomitant loss of RAG1/2-mediated antigen receptor gene rearrangement.

  5. Nonamer binding domain (NBD) of RAG1 plays a central role in the recognition of recombination signal sequence.

  6. Overall, these findings suggest that the V(D)J recombination-activating gene 1, RAG1, may play a role in long-term memory consolidation.

  7. propose that pre-B cells toggle between pre-BCR (zeige BCR ELISA Kits) signals and a RAG1 DNA double-strand break-dependent checkpoint to maintain genome stability while iteratively assembling Igl chain genes

  8. Study reports that RAG1 associates with chromatin at thousands of active promoters and enhancers in the genome of developing lymphocytes. The mouse and human genomes appear to have responded by reducing the abundance of "cryptic" recombination signals near RAG1 binding sites.

  9. The non-core region of RAG1 facilitates chromosomal V(D)J recombination in a ubiquitylation-dependent pathway.

  10. Based on our results, we propose that interaction of RAG2 (zeige RAG2 ELISA Kits) with RAG1 induces cooperative interactions of multiple binding sites, induced through conformational changes at the RAG1 interdomain boundary

Zebrafish Recombination Activating Gene 1 (RAG1) Interaktionspartner

  1. Differential gene expression following TLR stimulation in rag1-/- mutant zebrafish tissues and morphological descriptions of lymphocyte-like cell populations

  2. first report of any rag1(-/-) mutant vertebrate mounting a protective secondary immune response to a bacterial pathogen

  3. target-selected inactivation of the rag1 gene

  4. Rag1 has a role in developing zebrafish cortex-medullary regionalization

  5. by embryonic day 4, rag1 transcripts are seen in the pancreas

  6. Recombination signal sequences are recognized by rag1 protein.

  7. Rag1 expression is restricted to a subpopulation of zebrafish olfactory neurons projecting to the lateral olfactory bulb; Rag11 catalytic activity is not essential for axon targeting

  8. This report describes the leukocyte populations in a unique model, recombination activation gene 1-/- mutant zebrafish (rag1 mutants).

RAG1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.

Genbezeichner und Symbole assoziert mit RAG1

  • recombination activating gene 1 (Rag1) Antikörper
  • recombination activating gene 1 (RAG1) Antikörper
  • recombination activating gene 1 (rag1) Antikörper
  • recombinase activating protein (RAG-1) Antikörper
  • recombination activating gene 1 a (rag1) Antikörper
  • rag-1 Antikörper
  • rag1 Antikörper
  • rag1a Antikörper
  • RNF74 Antikörper

Bezeichner auf Proteinebene für RAG1

V(D)J recombination-activating protein 1 , recombination activation protein 1 , recombination activating gene 1 , recombination activating protein 1 , recombination-activating gene 1 , recombinase activating protein , V(D)J recombination-activating protein 1-like , RING finger protein 74 , recombinase activating gene 1 , etID309719.25 , recombinase , recombination activating protein

GENE ID SPEZIES
84600 Rattus norvegicus
466489 Pan troglodytes
483420 Canis lupus familiaris
506302 Bos taurus
619389 Monodelphis domestica
697322 Macaca mulatta
100049810 Equus caballus
100077097 Ornithorhynchus anatinus
100145555 Xenopus (Silurana) tropicalis
100395720 Callithrix jacchus
100447109 Pongo abelii
100595879 Nomascus leucogenys
397506 Sus scrofa
5896 Homo sapiens
19373 Mus musculus
423164 Gallus gallus
100328950 Oryctolagus cuniculus
30663 Danio rerio
100136833 Oncorhynchus mykiss
100337558 Xenopus laevis
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