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RIN3 is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases (see RAB5A\; MIM 179512) (Kajiho et al., 2003 [PubMed 12972505]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen RIN3 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal RIN3 Primary Antibody für IHC, IHC (p) - ABIN4350559
Vallet, Soares, Wani, Sophocleous, Warner, Salter, Ralston, Albagha: Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone. in Human molecular genetics 2015
RIN3 may be involved in endolysosomal transport-a process known to be important to development of early onset AD.
RIN3 may contribute to Paget's disease of bone susceptibility by affecting osteoclast function.
discovered novel interaction candidates for CD2AP (zeige Cd2ap Antikörper) and characterized subtle yet significant differences in the recognition preferences of its three SH3 domains for c-CBL (zeige CBL Antikörper), ALIX (zeige PDCD6IP Antikörper), and RIN3
The study reports a novel association between a variant within RIN3 and lower limb-bone mineral density and note its previous association with risk of Paget's disease.
RIN3 is a negative regulator of mast cell responses to SCF (zeige KITLG Antikörper)
RIN3 specifically acts as a GEF (zeige SLC2A4RG Antikörper) for Rab31 (zeige RAB31 Antikörper).
RIN3 biochemically characterized as the stimulator and stabilizer for GTP (zeige AK3 Antikörper)-Rab5 (zeige RAB5A Antikörper) plays an important role in the transport pathway from plasma membrane to early endosomes
Tyrosine-phosphorylation signals are involved in the RIN3 activation and translocation to early endocytic vesicles.
RIN3 is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases (see RAB5A\; MIM 179512) (Kajiho et al., 2003
ras and Rab interactor 3
, Ras and Rab interactor 3
, ras and Rab interactor 3-like
, RAB5 interacting protein 3
, ras interaction/interference protein 3
, Ras interaction/interference protein 3