Rap Guanine Nucleotide Exchange Factor (GEF) 6 Proteine (RAPGEF6)

Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Zusätzlich bieten wir Ihnen Rap Guanine Nucleotide Exchange Factor (GEF) 6 Antikörper (42) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RAPGEF6 51735 Q8TEU7
Ratte RAPGEF6 RAPGEF6 303141  
Maus RAPGEF6 RAPGEF6 192786  
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Top Rap Guanine Nucleotide Exchange Factor (GEF) 6 Proteine auf antikoerper-online.de

Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$11,073.30
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
Details

RAPGEF6 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) Interaktionspartnern

Human Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) Interaktionspartner

  1. local accumulation of PDZGEF at the apical membrane during establishment of epithelial polarity is mediated by electrostatic interactions between positively charged side chains in the PDZ domain and negatively charged phosphatidic acid.

  2. BAG3 (zeige BAG3 Proteine) overexpression increases cell adhesion in Cos7 cells, but not in PDZGEF2 gene knockdown cells indicating that PDZGEF2 is a critical partner for BAG3 (zeige BAG3 Proteine) in regulating cell adhesion

  3. the second PDZ domain from human phosphatase hPTP1E (zeige PTPN13 Proteine) in complex with a C-terminal peptide from the guanine nucleotide exchange factor (zeige RASGRF1 Proteine) RA-GEF-2 has been determined

  4. haplotypes underlying the SPEC2 (zeige CDC42SE2 Proteine)/PDZ-GEF2/acyl-CoA synthetase long-chain family member 6 (zeige ACSL6 Proteine) region are associated with schizophrenia

  5. PDZ-GEF2 plays a critical role in the maturation of adherens junctions.

  6. When males and females were analysed separately, SNP4 (rs31251) in PDZ-GEF2 is associated with schizophrenia in females in Han Chinese.

  7. JAM-A (zeige F11R Proteine) dimerization facilitates formation of a complex with Afadin and PDZ-GEF2 that activates Rap1A (zeige RAP1A Proteine), which regulates beta1 integrin levels and cell migration.

Mouse (Murine) Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) Interaktionspartner

  1. Study show that double knockout of Rapgef6 in Rapgef2 (zeige RAPGEF2 Proteine)-cKO mice (Rapgef2 (zeige RAPGEF2 Proteine)/6-dKO) results in marked enlargement of the ectopic cortical mass. While Rapgef2 (zeige RAPGEF2 Proteine)-cKO affects late-born neurons only, Rapgef2 (zeige RAPGEF2 Proteine)/6-dKO affects both early-born and late-born neurons in the developing brain.

  2. Rapgef6 deletion mice were impaired in hippocampal and amygdalar function and had reduced spine density and primary dendrite number in pyramidal neurons of the CA3 (zeige CA3 Proteine) hippocampal region.

  3. Data indicate that the testes of RA-GEF-2(-)knockout male mice were significantly smaller than those of wild-type mice and were markedly atrophied as well as hypospermatogenic.

  4. These findings proved a crucial role of the cross-talk between two Ras-family GTPases M-Ras (zeige MRAS Proteine) and Rap1 (zeige TERF2IP Proteine), mediated by RA-GEF-2, in adhesion signaling.

Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) Protein Überblick

Protein Überblick

Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.

Genbezeichner und Symbole assoziert mit RAPGEF6

  • Rap guanine nucleotide exchange factor (GEF) 6 (rapgef6)
  • Rap guanine nucleotide exchange factor (GEF) 6 (RAPGEF6)
  • folliculin interacting protein 1 (FNIP1)
  • Rap guanine nucleotide exchange factor 6 (RAPGEF6)
  • Rap guanine nucleotide exchange factor 6 (rapgef6)
  • Rap guanine nucleotide exchange factor 6 (Rapgef6)
  • Rap guanine nucleotide exchange factor (GEF) 6 (Rapgef6)
  • A530068K01 Protein
  • AI844632 Protein
  • BB085664 Protein
  • C030018K18Rik Protein
  • KIA001LB Protein
  • mKIAA4052 Protein
  • PDZ-GEF2 Protein
  • Pdzgef2 Protein
  • RA-GEF-2 Protein
  • Ragef2 Protein
  • RAPGEF6 Protein
  • wu:fa12b02 Protein

Bezeichner auf Proteinebene für RAPGEF6

Rap guanine nucleotide exchange factor (GEF) 6 , PDZ domain-containing guanine nucleotide exchange factor I , rap guanine nucleotide exchange factor 6-like , PDZ domain containing guanine nucleotide exchange factor (GEF) 2 , PDZ domain-containing guanine nucleotide exchange factor 2 , rap guanine nucleotide exchange factor 6 , PDZ domain containing guanine nucleotide exchange factor(GEF)1 , rap guanine nucleotide exchange factor 2

GENE ID SPEZIES
335032 Danio rerio
416322 Gallus gallus
481496 Canis lupus familiaris
706541 Macaca mulatta
733941 Xenopus (Silurana) tropicalis
743392 Pan troglodytes
789597 Bos taurus
100015023 Monodelphis domestica
100063392 Equus caballus
100386485 Callithrix jacchus
100482379 Ailuropoda melanoleuca
100521255 Sus scrofa
100553829 Anolis carolinensis
100591273 Nomascus leucogenys
51735 Homo sapiens
303141 Rattus norvegicus
192786 Mus musculus
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