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human homolog is a GTPase and member of the RAS oncogene family [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen RAP2A Antikörper (29) und viele weitere Produktgruppen zu diesem Protein an.
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The small GTPase (zeige RACGAP1 Proteine) Ras-related protein (zeige RASD1 Proteine) 2 (Rap2) was found to bind ArrB1 (zeige ARRB1 Proteine) under resting conditions but dissociated upon formyl-Met-Leu-Phe stimulation.
Nedd4-1 (zeige NEDD4 Proteine) inhibited Rap2a activity, and promoted the migration and invasion of glioma cells.
present review mainly focused on recent studies on the functional and physical interactions between Rap2 and its effectors. We also speculated on the relevance of these pathways to tumorigenesis
Single nucleotide polymorphism in RAP2A gene is associated with Peripheral Arterial Disease.
the role of Rap2a in carcinogenesis
The ectopic expression of Rap2a enhances the migration and invasive ability of cancer cells and increases activities of matrix metalloproteinase MMP2 (zeige MMP2 Proteine) and MMP9 (zeige MMP9 Proteine).
Phosphorylation of synaptic GTPase-activating protein (zeige RASA1 Proteine) (synGAP (zeige SYNGAP1 Proteine)) by Ca2+/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 5 (CDK5 (zeige CDK5 Proteine)) alters the ratio of its GAP activity toward Ras and Rap (zeige LRPAP1 Proteine) GTPases.
downregulation of Rap2a promoted glioma migration and invasion, and raised the phosphorylation level of AKT (zeige AKT1 Proteine)
endothelial barrier resistance is determined by the combined antagonistic actions of Rap1 (zeige RABGEF1 Proteine) and Rap2
Rap2A and TNIK (zeige TNIK Proteine) control brush border formation by apical recruitment of MST4 (zeige MST4 Proteine) and the subsequent phosphorylation of Ezrin (zeige EZR Proteine)
BCR (zeige BCR Proteine)-induced phosphorylation of Akt (zeige AKT1 Proteine) on critical activating sites was increased 2- to 3-fold when Rap1 (zeige TERF2IP Proteine) and Rap2 activation was blocked
Rap2 has a role in regulation of integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 (zeige PTK2B Proteine) tyrosine phosphorylation in B lymphocytes
human homolog is a GTPase and member of the RAS oncogene family
ras-related protein Rap-2a
, RAS related protein 2a inverted question mark
, rap2A-like protein
, RAP2A, member of RAS oncogene family
, Rap2A GTPase
, RAP2, member of RAS oncogene family (K-rev)
, RAP2B member of RAS oncogene family
, Ras-related protein Rap-2a