anti-RAP1 GTPase Activating Protein (RAP1GAP) Antikörper

RAP1GAP encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Zusätzlich bieten wir Ihnen RAP1 GTPase Activating Protein Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RAP1GAP 5909 P47736
RAP1GAP 110351  
RAP1GAP 313644  
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Top anti-RAP1 GTPase Activating Protein Antikörper auf antikoerper-online.de

Showing 10 out of 36 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RAP1GAP Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate WB Suggested Anti-RAP1GAP <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control:.93T cell lysate <br /> RAP1GAP is supported by BioGPS gene expression data to be expressed in HEK293T 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RAP1GAP Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Transfected 293T WB Suggested Anti-RAP1GAP <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Transfected 293T 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Western Blot: RAP1GAP Antibody [NBP1-83002] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18.Lane 2: Human cell line RT-4 Immunocytochemistry/Immunofluorescence: RAP1GAP Antibody [NBP1-83002] - Staining of mouse globus pallidus shows strong cytoplasmic immunoreactivity in neurons. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-RAP1GAP Polyclonal Antibody, Unconjugated (ABIN681673) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western Blot (WB) analysis of specific cells using Rap1GAP Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of RAP1GAP staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RAP1GAP expression in Jurkat (A), HeLa (B), mouse brain (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, WB Western Blot: RAP1GAP Antibody [NBP1-53072] - Human 721_B, Antibody Dilution: 1.0 ug/ml RAP1GAP is supported by BioGPS gene expression data to be expressed in 721_B. Immunohistochemistry: RAP1GAP Antibody [NBP1-53072] - Human Hela, Antibody Dilution: 1.0 ug/ml RAP1GAP is supported by BioGPS gene expression data to be expressed in HeLa. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged RAP1GA1 is approximately 1 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details

RAP1GAP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , ,
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Mouse (Murine) ,


Rat (Rattus)


Am meisten referenzierte anti-RAP1 GTPase Activating Protein Antikörper

  1. Human Polyclonal RAP1GAP Primary Antibody für ICC, IF - ABIN4349349 : Mulder, Björling, Jonasson, Wernérus, Hober, Hökfelt, Uhlén: Tissue profiling of the mammalian central nervous system using human antibody-based proteomics. in Molecular & cellular proteomics : MCP 2009 (PubMed)

Weitere Antikörper gegen RAP1 GTPase Activating Protein Interaktionspartner

Human RAP1 GTPase Activating Protein (RAP1GAP) Interaktionspartner

  1. results have shown a novel role of PLCepsilon in the maintenance of endothelial barrier function, via its CDC25 GEF domain and lipase activity, and subsequent up-regulation of Rap1 activity

  2. Findings suggest that RAP1 GTPase activating protein (Rap1GAP) is an important tumor suppressor with high prognostic value in endometrioid adenocarcinoma (EAC (zeige CYLD Antikörper)).

  3. Rap1GAP is ubiquitinated and degraded through proteasome pathway in mitosis. Rap1GAP interacts with PLK1 (zeige PLK1 Antikörper) in vivo.

  4. kidney biopsies from glomerulosclerosis patients exhibited increased RAP1GAP, resulting in diminished glomerular RAP1 activation

  5. findings identify Rap1GAP as a critical regulator of aggressive tumor cell behavior and suggest that the level of Rap1GAP expression influences the migratory mechanisms that are operative in tumor cells.

  6. Results demonstrated that Rap1GAP promoted leukemia cell differentiation and apoptosis, but increased leukemia cell invasion in vitro.

  7. Downregulation of RAP1GAP in thyroid tumors enhances SRC (zeige SRC Antikörper)-dependent signals that regulate cellular architecture and motility.

  8. Over-expression of Rap1GAP attenuated levels of both cadherins and integrins that are known to regulate the cancer cells invasion in renal cel carcinoma.

  9. Rap1GAP is a more effective inhibitor of cell-matrix adhesion compared to cell-cell adhesion.

  10. A polycomb (zeige CBX2 Antikörper)-mediated repression of rap1GAP was demonstrated that involves EZH2 (zeige EZH2 Antikörper), a histone methyltransferase in head and neck cancers. It was also shown that the loss of miR (zeige MLXIP Antikörper)-101 expression correlates with EZH2 (zeige EZH2 Antikörper) upregulation and rap1GAP downregulation.

Mouse (Murine) RAP1 GTPase Activating Protein (RAP1GAP) Interaktionspartner

  1. increased podocyte expression of RAP1GAP contributes directly to podocyte dysfunction by a mechanism that involves loss of RAP1-mediated activation of beta1 integrin

  2. Plexins are GTPase (zeige RACGAP1 Antikörper)-activating proteins for Rap (zeige LRPAP1 Antikörper) and are activated by induced dimerization

  3. Ca2 (zeige CA2 Antikörper)+-dependent monomer and dimer formation switches CAPRI (zeige RASA4 Antikörper) Protein between Ras GTPase-activating protein (zeige RASA1 Antikörper) (GAP) and RapGAP activities

  4. ERK activation by cAMP does not require RAP1

  5. evidence of differential Krit1 (zeige KRIT1 Antikörper) and Rap1A (zeige RAP1A Antikörper) expression during mouse ontogenesis and suggest a more widespread functional significance of Krit1 (zeige KRIT1 Antikörper), not restricted to vascular endothelial cells.

  6. Rap1 (zeige TERF2IP Antikörper) couples cAMP signaling to a distinct pool of p42 (zeige EPB42 Antikörper)/44MAPK regulating excitability, synaptic plasticity, learning, and memory.

  7. Expression studies show that mr-gef (zeige RAPGEF5 Antikörper) is expressed by young neurons of the developing rodent CNS but not by progenitor cells in the ventricular zone (VZ).

  8. down-regulation of Rap1 (zeige TERF2IP Antikörper) expression following somatostatin (zeige SST Antikörper) treatment is closely related to the diminished LFA-1 (zeige ITGAL Antikörper) expression

  9. forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling

  10. EGF (zeige EGF Antikörper)-induced activation of GTPase (zeige RACGAP1 Antikörper) Rap1 (zeige TERF2IP Antikörper) was sensitized in NIH3T3/EGFR (zeige EGFR Antikörper)-e3B1 (zeige ABI1 Antikörper) cells.

Zebrafish RAP1 GTPase Activating Protein (RAP1GAP) Interaktionspartner

  1. a proper level of Rap1 is crucial for heart morphogenesis and function.

  2. the direct interaction between Rap1 (zeige TERF2IP Antikörper) and KRIT1 (zeige KRIT1 Antikörper) is required for KRIT1 (zeige KRIT1 Antikörper) function in cardiovascular development

RAP1 GTPase Activating Protein (RAP1GAP) Antigen-Profil

Protein Überblick

This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Genbezeichner und Symbole assoziert mit RAP1GAP

  • RAP1 GTPase activating protein (RAP1GAP) Antikörper
  • Rap1 GTPase-activating protein (Rap1gap) Antikörper
  • RAP1 GTPase activating protein 1 (RAP1GAP1) Antikörper
  • RAP1 GTPase activating protein L homeolog (rap1gap.L) Antikörper
  • Rap1 GTPase-activating protein 1 (Tsp_09520) Antikörper
  • RAP1 GTPase activating protein (rap1gap) Antikörper
  • si:dkey-166d12.2 (si:dkey-166d12.2) Antikörper
  • RAP1 GTPase activating protein (Rap1gap) Antikörper
  • 1300019I11Rik Antikörper
  • 2310004O14Rik Antikörper
  • AI427470 Antikörper
  • DKFZp459A114 Antikörper
  • RAP1 Antikörper
  • rap1ga1 Antikörper
  • RAP1GAP Antikörper
  • rap1gap1 Antikörper
  • rap1gapii Antikörper
  • rapgap Antikörper
  • zgc:175180 Antikörper

Bezeichner auf Proteinebene für RAP1GAP

rap1 GTPase-activating protein 1 , Rap1, GTPase-activating protein 1 , GTPase activating protein 1 , GTPase activating protein Rap1-GAP , RAP1, GTPase activating protein 1 , Rap1 GTPase-activating protein 1

GENE ID SPEZIES
5909 Homo sapiens
110351 Mus musculus
313644 Rattus norvegicus
395647 Gallus gallus
494835 Xenopus laevis
532839 Bos taurus
10902864 Trichinella spiralis
100144557 Danio rerio
100172787 Pongo abelii
100538309 Danio rerio
100725658 Cavia porcellus
100340849 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-RAP1 GTPase Activating Protein (RAP1GAP) Antikörper
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