anti-RAD18 Homolog (S. Cerevisiae) (RAD18) Antikörper

The protein encoded by RAD18 is highly similar to S. Zusätzlich bieten wir Ihnen RAD18 Proteine (6) und RAD18 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RAD18 56852 Q9NS91
RAD18 58186 Q9QXK2
RAD18 362412  
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Top anti-RAD18 Antikörper auf antikoerper-online.de

Showing 10 out of 104 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-RAD18 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-RAD18 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control:.21_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-RAD18 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: COLO205 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to RAD18 on HeLa cell (antibody concentration 25 µg/mL). Western blot analysis of RAD18 over-expressed 293 cell line, cotransfected with RAD18 Validated Chimera RNAi used as specificity and loading control. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Maus Unkonjugiert WB The anti-Rad18 mAb (Imgenex Cat#ABIN252484) was diluted at 2 ug/ml and tested against 20 ug of HL-60 cell lysate. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Maus Unkonjugiert WB RAD18 monoclonal antibody (M03), clone 2B9. Western Blot analysis of RAD18 expression in Hela NE. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IP Western Blot: RAD18 Antibody [ABIN253201] - Detection of Human RAD18 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-RAD18 antibody ABIN253201 used for IP at 3 mcg/mg lysate. RAD18 was also immunoprecipitated by rabbit anti- RAD18 antibody ABIN253202, which recognizes a downstream epitope.  Detection: Chemiluminescence with an exposure time of 3 seconds. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert IP, PLA, WB Western Blot and Immunoprecipitation: RAD18 Antibody [ABIN253202] - Detection of Human RAD18 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- RAD18 antibody ABIN253202 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. RAD18 was also immunoprecipitated by rabbit anti-RAD18 antibody ABIN253201, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds Proximity Ligation Assay: RAD18 Antibody [ABIN2532023] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human ATM (ABIN253202) and rabbit anti-human RAD18 (ABIN2532023). Image merged from DAPI (2ms) and Texas Red (200ms) exposures, 40X magnification. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert IF, IHC (p), RNAi, ELISA, WB RAD18 monoclonal antibody (M01), clone 3H7 Western Blot analysis of RAD18 expression in Hela S3 NE . Immunofluorescence of monoclonal antibody to RAD18 on HeLa cell. [antibody concentration 25 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details

RAD18 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)


Rat (Rattus)
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Am meisten referenzierte anti-RAD18 Antikörper

  1. Human Monoclonal RAD18 Primary Antibody für IF, IHC (p) - ABIN566046 : Hicks, Chute, Paulsen, Ragland, Howlett, Guéranger, Glover, Canman: Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. in Molecular and cellular biology 2010 (PubMed)
    Show all 7 Pubmed References

  2. Mouse (Murine) Polyclonal RAD18 Primary Antibody für IF, IP - ABIN2452085 : Sun, Yomogida, Sakao, Yamamoto, Yoshida, Watanabe, Morita, Araki, Yamamura, Tateishi: Rad18 is required for long-term maintenance of spermatogenesis in mouse testes. in Mechanisms of development 2009 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal RAD18 Primary Antibody für IF, IP - ABIN2452086 : Tateishi, Sakuraba, Masuyama, Inoue, Yamaizumi: Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal RAD18 Primary Antibody für IP, PLA - ABIN253202 : Williams, Longerich, Sung, Vaziri, Kupfer: The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI. in Blood 2011 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal RAD18 Primary Antibody für WB - ABIN252484 : Lyakhovich, Shekhar: Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced response. in Molecular and cellular biology 2003 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal RAD18 Primary Antibody für IP - ABIN253201 : Wagner, Karnitz: Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival. in Molecular pharmacology 2009 (PubMed)

  7. Cow (Bovine) Polyclonal RAD18 Primary Antibody für WB - ABIN2774765 : Tsuji, Watanabe, Araki, Shinohara, Yamagata, Tsurimoto, Hanaoka, Yamamura, Yamaizumi, Tateishi: Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks. in Genes to cells : devoted to molecular & cellular mechanisms 2008 (PubMed)

Weitere Antikörper gegen RAD18 Interaktionspartner

Human RAD18 Homolog (S. Cerevisiae) (RAD18) Interaktionspartner

  1. Ubiquitin ligases RNF168 (zeige RNF168 Antikörper), RNF169 (zeige RNF169 Antikörper), and RAD18 specifically bind histone H2A Lys13/15-ubiquitylated nucleosomes. 53BP1 (zeige TP53BP1 Antikörper) chromatin recruitment may be activated by RNF168 (zeige RNF168 Antikörper) and blocked by RNF169 (zeige RNF169 Antikörper) and RAD18.

  2. WRNIP1 (zeige WRNIP1 Antikörper) connects PCNA (zeige PCNA Antikörper) monoubiquitination with ATMIN (zeige ATMIN Antikörper)/ATM (zeige ATM Antikörper) to activate ATM (zeige ATM Antikörper) signalling in response to replication stress and contribute to the maintenance of genomic stability.

  3. RAD18 polymorphisms are correlated with the side effects of platinum-chemotherapy in Chinese patients with advanced NSCLC.

  4. REV1 (zeige REV1 Antikörper) can promote (zeige PCNA Antikörper)PCNA monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18.

  5. USP7 (zeige USP7 Antikörper)-mediated de-ubiquitylation protects Rad18 from proteasomal degradation and is necessary for the integrity of the specialized translesion synthesis pathway

  6. RAD18 can function as a mediator for DNA damage response signals to activate the G2/M checkpoint in order to maintain genome integrity and cell survival after IR exposure.

  7. Significantly restored tolerance of RAD18-/- and RNF8 (zeige RNF8 Antikörper)-/- cells to camptothecin and olaparib without affecting Rad51 (zeige RAD51 Antikörper) focus formation.

  8. these results suggest that miR (zeige MLXIP Antikörper)-145 can act as an RAD18 inhibitor and contribute as an important factor in reversing drug resistance after chemotherapy.

  9. We obtained a molecular envelope for Rad18 UBZ-ELRM:linear Ub2 polyubiquitin (zeige UBB Antikörper) chains by small-angle X-ray scattering and derived a structural model for the complex.

  10. Rad18 protein ubiquitin-binding zinc fingers domain has alpha-helix and strand beta1 conformation.

Mouse (Murine) RAD18 Homolog (S. Cerevisiae) (RAD18) Interaktionspartner

  1. Somatic hypermutation of immunoglobulin genes (SHM (zeige CNTNAP1 Antikörper)) in Rad18 KO mice was similar to wild-type mice, suggesting that Rad18 is dispensable for SHM (zeige CNTNAP1 Antikörper).

  2. Rad18 confers DNA damage tolerance and tumor-suppression in a physiological setting.

  3. REV1 promote PCNA (zeige PCNA Antikörper) monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18.

  4. RAD18 can function as a mediator for DNA damage response signals to activate the G2/M checkpoint in order to maintain genome integrity and cell survival after IR exposure.

  5. RAD18 contributes to maintenance of genomic stability through postreplication repair

  6. Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase

  7. Rad18 suppresses viral infection in a non-specific fashion, probably by targeting incoming DNA.

  8. RAD18 is intrinsically required for the long-term maintenance of spermatogenesis.

RAD18 Antigen-Profil

Protein Überblick

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

Genbezeichner und Symbole assoziert mit RAD18

  • RAD18, E3 ubiquitin protein ligase (RAD18) Antikörper
  • RAD18 E3 ubiquitin protein ligase (Rad18) Antikörper
  • RAD18 E3 ubiquitin protein ligase (rad18) Antikörper
  • E3 ubiquitin-protein ligase RAD18 (RAD18) Antikörper
  • E3 ubiquitin-protein ligase (RAD18) Antikörper
  • DNA repair protein and ATPase (RAD18) Antikörper
  • C3HC4-type zinc finger-containing protein (rad18) Antikörper
  • RAD18, E3 ubiquitin protein ligase (Rad18) Antikörper
  • 2810024C04Rik Antikörper
  • DDBDRAFT_0218120 Antikörper
  • DDBDRAFT_0304878 Antikörper
  • DDB_0218120 Antikörper
  • DDB_0304878 Antikörper
  • DKFZp469H0810 Antikörper
  • RAD18 Antikörper
  • Rad18sc Antikörper
  • RNF73 Antikörper
  • zgc:55577 Antikörper

Bezeichner auf Proteinebene für RAD18

E3 ubiquitin-protein ligase RAD18 , RAD18, S. cerevisiae, homolog , RING finger protein 73 , hHR18 , hRAD18 , postreplication repair protein RAD18 , postreplication repair protein hRAD18p , mRAD18Sc , post-replication repair protein RAD18SC , RAD18 homolog (S. cerevisiae) , similar to postreplication repair protein hRAD18p , E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair , Rad18p , hypothetical protein , DNA repair protein and ATPase , SAP DNA-binding domain-containing protein , RAD18 homolog , RAD18-like protein , E3 ubiquitin-protein ligase RAD18-like , e3 ubiquitin-protein ligase RAD18-like

GENE ID SPEZIES
56852 Homo sapiens
58186 Mus musculus
362412 Rattus norvegicus
393106 Danio rerio
416114 Gallus gallus
460144 Pan troglodytes
476544 Canis lupus familiaris
514440 Bos taurus
704708 Macaca mulatta
850430 Saccharomyces cerevisiae S288c
3641637 Candida albicans SC5314
4839641 Scheffersomyces stipitis CBS 6054
8621702 Dictyostelium discoideum AX4
100052645 Equus caballus
100172537 Pongo abelii
100217383 Sus scrofa
100395032 Callithrix jacchus
100473633 Ailuropoda melanoleuca
100591424 Nomascus leucogenys
100720939 Cavia porcellus
Ausgewählte Anbieter für anti-RAD18 (RAD18) Antikörper
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