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RAD1 Homolog (S. Pombe) (RAD1) ELISA Kits

RAD1 encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. Zusätzlich bieten wir Ihnen RAD1 Antikörper (87) und RAD1 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte RAD1 RAD1 294800  
Anti-Human RAD1 RAD1 5810 O60671
Anti-Maus RAD1 RAD1 19355 Q9QWZ1
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Weitere ELISA Kits für RAD1 Interaktionspartner

Human RAD1 Homolog (S. Pombe) (RAD1) Interaktionspartner

  1. Intramolecular binding of the rad9 (zeige RAD9A ELISA Kits) C-terminus in the checkpoint clamp (zeige PDZK1 ELISA Kits) Rad9 (zeige RAD9A ELISA Kits)-Hus1 (zeige HUS1 ELISA Kits)-Rad1 (zeige ERCC4 ELISA Kits) is closely linked with its DNA binding.

  2. Data show models for the ternary PCNA (zeige PCNA ELISA Kits)/FEN1 (zeige FEN1 ELISA Kits)/DNA and Rad9 (zeige RAD9A ELISA Kits)-Rad1 (zeige ERCC4 ELISA Kits)-Hus1 (zeige HUS1 ELISA Kits) (9-1-1 complex)/FEN1 (zeige FEN1 ELISA Kits)/DNA assemblies.

  3. The RAD1 (zeige ERCC4 ELISA Kits) is loaded to damaged sites where it serves as a platform for the selective recruitment of checkpoint and repair proteins.

  4. CK2 (zeige CSNK2A1 ELISA Kits) plays a crucial role in the ATR (zeige ANTXR1 ELISA Kits)-dependent checkpoint pathway through its ability to phosphorylate Ser (zeige SIGLEC1 ELISA Kits)-341 and Ser (zeige SIGLEC1 ELISA Kits)-387 of the Rad9 (zeige RAD9A ELISA Kits) subunit of the Rad9 (zeige RAD9A ELISA Kits)-Hus1 (zeige HUS1 ELISA Kits)-Rad1 (zeige ERCC4 ELISA Kits) complex

  5. Rad9 (zeige RAD9A ELISA Kits)-Rad1 (zeige ERCC4 ELISA Kits)-Hus1 (zeige HUS1 ELISA Kits) complex enhances in vitro activity of 8-oxoguanine DNA glycosylase (zeige OGG1 ELISA Kits).

  6. Rad9 (zeige RAD9A ELISA Kits), Hus1 (zeige HUS1 ELISA Kits), and Rad1 (zeige ERCC4 ELISA Kits) heterotrimeric complex chromatin binding is a proximal event in the checkpoint signaling cascade

  7. RAD1 (zeige ERCC4 ELISA Kits) is a potential intrinsic chaperone in the stabilization of HUS1 (zeige HUS1 ELISA Kits) for the heterotrimeric (RAD9 (zeige RAD9A ELISA Kits)-RAD1 (zeige ERCC4 ELISA Kits)-HUS1 (zeige HUS1 ELISA Kits)) checkpoint complex formation.

  8. The human Rad9 (zeige RAD9A ELISA Kits)/Rad1 (zeige ERCC4 ELISA Kits)/Hus1 (zeige HUS1 ELISA Kits) complex interacts with and stimulates DNA polymerase beta (zeige POLB ELISA Kits) activity.

  9. complex with rad9 (zeige RAD9A ELISA Kits) and hus1 (zeige HUS1 ELISA Kits) is a damage-specific activator of flap endonuclease 1 (zeige FEN1 ELISA Kits)

  10. The long-patch base excision machinery is an important target of the Rad9 (zeige RAD9A ELISA Kits)-Rad1 (zeige ERCC4 ELISA Kits)-Hus1 (zeige HUS1 ELISA Kits) complex, thus enhancing the quality control of DNA.

Mouse (Murine) RAD1 Homolog (S. Pombe) (RAD1) Interaktionspartner

  1. HUS1 (zeige HUS1 ELISA Kits) acts as a component of the canonical 9-1-1 complex during meiotic prophase I to promote DSB repair and further propose that RAD1 and TOPBP1 (zeige TOPBP1 ELISA Kits) respond to unsynapsed chromatin through an alternative mechanism that does not require RAD9 (zeige RAD9A ELISA Kits) or HUS1 (zeige HUS1 ELISA Kits).

  2. The rad1 protein is required for repairing DNA lesions induced by UV-light, HU and gamma rays, and for mediating G(2)/M and S/M checkpoint controls.

  3. data indicate that Rad1(K185) is not a functional counterpart of PCNA (zeige PCNA ELISA Kits)(K164).

  4. data suggest that Mrad1 is important for preventing tumor development.

RAD1 Antigen-Profil

Beschreibung des Gens

This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.

Genbezeichner und Symbole assoziert mit RAD1

  • RAD1 homolog (S. pombe) (Rad1) Antikörper
  • RAD1 homolog (S. pombe) (rad1) Antikörper
  • RAD1 homolog (S. pombe) (RAD1) Antikörper
  • RAD1 homolog (rad1) Antikörper
  • RAD1 homolog (RAD1) Antikörper
  • DKFZp459H1127 Antikörper
  • HRAD1 Antikörper
  • RAD1 Antikörper
  • REC1 Antikörper
  • xrad1 Antikörper
  • zgc:56502 Antikörper
  • zgc:77779 Antikörper

Bezeichner auf Proteinebene für RAD1

cell cycle checkpoint protein RAD1 , RAD1 homolog (S. pombe) , RAD1 homolog , Cell cycle checkpoint protein RAD1 , cell cycle checkpoint protein rad1 , DNA repair exonuclease REC1 , DNA repair exonuclease rad1 homolog , cell cycle checkpoint protein Hrad1 , checkpoint control protein HRAD1 , exonuclease homolog RAD1 , rad1-like DNA damage checkpoint protein , mRAD1

GENE ID SPEZIES
294800 Rattus norvegicus
393872 Danio rerio
427432 Gallus gallus
461928 Pan troglodytes
479366 Canis lupus familiaris
518502 Bos taurus
548799 Xenopus (Silurana) tropicalis
100173217 Pongo abelii
100528686 Ictalurus punctatus
740886 Pan troglodytes
5810 Homo sapiens
19355 Mus musculus
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