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RAB6A encodes a member of the RAB family, which belongs to the small GTPase superfamily. Zusätzlich bieten wir Ihnen RAB6A, Member RAS Oncogene Family Antikörper (65) und viele weitere Produktgruppen zu diesem Protein an.
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Human RAB6A Protein expressed in Escherichia coli (E. coli) - ABIN667298
Burguete, Fenn, Brunger, Pfeffer: Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. in Cell 2008
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Data show that basal body docking was unaffected in dynein 1 (dync1h1) mutation, but rab GTP-binding protein Rab6 expression was reduced.
Ectopic expression of an N-terminal-truncated ARHGEF10 (zeige ARHGEF10 Proteine) mutant led to the generation of large vesicle-like structures containing both Rab6 and Rab8 (zeige RAB8A Proteine).
Rab6A binding to KIF1C's motor domain represents an entirely new mode of regulation for a kinesin motor, and likely has important consequences for KIF1C's cellular functions.
GORAB missense mutation disrupt RAB6 protein binding in genetic skin diseases.
several analyses of vesicular transport demonstrated that Rab6A and BICD2 play crucial roles in Golgi tubule fusion with the endoplasmic reticulum (ER) in brefeldin A (BFA)-treated cells
Data suggest that miR-5100 promotes tumor growth by facilitating the G1/S transition and targeting Rab6.
Data indicate that myosin Va (zeige MYO5A Proteine) interacted with multiple new Rab (zeige HRB Proteine) subfamilies including Rab6, Rab14 (zeige RAB14 Proteine) and Rab39B (zeige RAB39B Proteine).
Mint1 826 bridges APP (zeige APP Proteine) to the small GTPase (zeige RACGAP1 Proteine)
The presence of an active pool of Rab6 within host cells early during infection is required to support efficient intracellular growth of L. pneumophila.
Ric1-Rgp1 complex is a guanine nucleotide exchange factor (zeige RASGRF1 Proteine) for the late Golgi Rab6A GTPase (zeige RACGAP1 Proteine) and an effector of the medial Golgi Rab33B (zeige RAB33B Proteine) GTPase (zeige RACGAP1 Proteine).
GTP (zeige AK3 Proteine)-bound form of Rab6 promotes retrograde trafficking of cav-2 (zeige CAV2 Proteine) from the Golgi to ER
The data reveal that Rab6a not only participates in modulating the organization of oocyte organelles, but also is a novel regulator of meiotic apparatus in mammalian oocytes.
Rab6a knockdown in oocytes may compromise the interaction between kinetochore and microtubule, which in turn leads to the activation of spindle assembly checkpoint signal, and, as a result, chromosome misalignment and spindle defects are established during meiosis, causing the production of aneuploid eggs and persistent defects in embryos.
Our study shows that RAB6 is an essential gene required for normal embryonic development
Rab6 GTPase (zeige RACGAP1 Proteine) was required during the phagosome maturation by its interaction with bicaudal-D1 (BICD1 (zeige BICD1 Proteine)) protein. Further data presented that the Rab6 GTPase (zeige RACGAP1 Proteine)-regulated phagocytosis could influence the proliferation of Staphylococcus aureus in macrophages.
Rab6a(Q72L) mediates LIS1 release from a LIS1-dynein complex followed by dynein activation
Rab6a/a' are important Golgi regulators of pro-inflammatory TNF (zeige TNF Proteine) secretion in macrophages.
Rab1 and Rab6 GTPases may play a role in modulating the function of retina by mediating the transport of nascent proteins along the early secretary pathway, particularly in the process of the light adaptation.
Rab6 recruits Rab6-interacting protein 1 on Golgi membranes.
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
RAB6A, member RAS oncogene family
, RAB6, member RAS oncogene family
, ras-related protein Rab-6A
, Ras-related protein Rab-6A
, Rab GTPase
, RAB6B, member RAS oncogene family