anti-RAB4A, Member RAS Oncogene Family (RAB4A) Antikörper

may play a role in intracellular recruitment of the glucose transporter GLUT4. Zusätzlich bieten wir Ihnen RAB4A, Member RAS Oncogene Family Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RAB4A 5867 P20338
RAB4A 19341 P56371
RAB4A 25532 P05714
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Showing 10 out of 103 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-RAB4A Antibody Titration: 1.0 ug/ml Positive Control: Fetal Stomach 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Hund Maus Unkonjugiert IF, WB Western blot analysis of Rab4 on a rat cerebrum lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the anti-Rab4 antibody. Immunofluorescence staining of L6 cells (rat skeletal muscle myoblasts, ATCC CRL-1458). 50 μg Anmelden zum Anzeigen 2 bis 4 Tage
146,73 €
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Human Maus Unkonjugiert FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of MCF-7 cells using RAB4A mouse mAb (green) and negative control (red) . 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
494,23 €
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Human Kaninchen Unkonjugiert ICC, IF, IHC, WB Rab4, Hela 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
361,58 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-RAB4 Polyclonal Antibody, Unconjugated (ABIN763256) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C and DAPI staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Human Maus Unkonjugiert CyTOF, ELISA, FACS, IHC, WB Western Blot: Rab4 Antibody (4E11) [NBP2-37485] - Western blot analysis using RAB4A mAb against human RAB4A (AA: 22-218) recombinant protein. (Expected MW is 47.9 kDa) ELISA: Rab4 Antibody (4E11) [NBP2-37485] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng); 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Kaninchen HRP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-Rab4 Polyclonal Antibody . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Rabbit Anti-Rab4 Polyclonal Antibody  at 1:150 for 12 hours at 4°C. Secondary Antibody: R-PE Goat Anti-Rabbit (yellow) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Membrane. Cytoplasm. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-Rab4 Antibody. (C) Composite. Heat Shocked at 42°C for 30 min. Western blot analysis of Human HeLa cell lysates showing detection of Rab4 protein using Rabbit Anti-Rab4 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-Rab4 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
403,49 €
Details
Human Kaninchen FITC ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-Rab4 Polyclonal Antibody . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Rabbit Anti-Rab4 Polyclonal Antibody  at 1:150 for 12 hours at 4°C. Secondary Antibody: R-PE Goat Anti-Rabbit (yellow) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Membrane. Cytoplasm. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-Rab4 Antibody. (C) Composite. Heat Shocked at 42°C for 30 min. Western blot analysis of Human HeLa cell lysates showing detection of Rab4 protein using Rabbit Anti-Rab4 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-Rab4 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
408,28 €
Details
Human Kaninchen Alkaline Phosphatase (AP) ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-Rab4 Polyclonal Antibody . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Rabbit Anti-Rab4 Polyclonal Antibody  at 1:150 for 12 hours at 4°C. Secondary Antibody: R-PE Goat Anti-Rabbit (yellow) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Membrane. Cytoplasm. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-Rab4 Antibody. (C) Composite. Heat Shocked at 42°C for 30 min. Western blot analysis of Human HeLa cell lysates showing detection of Rab4 protein using Rabbit Anti-Rab4 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-Rab4 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
410,67 €
Details
Human Kaninchen Biotin ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-Rab4 Polyclonal Antibody . Tissue: Heat Shocked HeLa Cells. Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Rabbit Anti-Rab4 Polyclonal Antibody  at 1:150 for 12 hours at 4°C. Secondary Antibody: R-PE Goat Anti-Rabbit (yellow) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Membrane. Cytoplasm. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-Rab4 Antibody. (C) Composite. Heat Shocked at 42°C for 30 min. Western blot analysis of Human HeLa cell lysates showing detection of Rab4 protein using Rabbit Anti-Rab4 Polyclonal Antibody . Load: 15 µg protein. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Rabbit Anti-Rab4 Polyclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Donkey Anti-Rabbit IgG: HRP for 1 hour at RT. 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
413,06 €
Details

RAB4A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-RAB4A, Member RAS Oncogene Family Antikörper

  1. Dog (Canine) Monoclonal RAB4A Primary Antibody für IF, WB - ABIN968233 : Cormont, Bortoluzzi, Gautier, Mari, van Obberghen, Le Marchand-Brustel: Potential role of Rab4 in the regulation of subcellular localization of Glut4 in adipocytes. in Molecular and cellular biology 1997 (PubMed)
    Show all 5 Pubmed References

  2. Dog (Canine) Monoclonal RAB4A Primary Antibody für IF, WB - ABIN968232 : Huang, Imamura, Olefsky: Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal RAB4A Primary Antibody für ICC, IF - ABIN361841 : Ali, Wasmeier, Lamoreux, Strom, Seabra: Multiple regions contribute to membrane targeting of Rab GTPases. in Journal of cell science 2004 (PubMed)
    Show all 8 Pubmed References

  4. Human Monoclonal RAB4A Primary Antibody für FACS, IHC - ABIN969558 : Ferrándiz-Huertas, Fernández-Carvajal, Ferrer-Montiel: Rab4 interacts with the human P-glycoprotein and modulates its surface expression in multidrug resistant K562 cells. in International journal of cancer. Journal international du cancer 2010 (PubMed)

Weitere Antikörper gegen RAB4A, Member RAS Oncogene Family Interaktionspartner

Human RAB4A, Member RAS Oncogene Family (RAB4A) Interaktionspartner

  1. These findings bring attention to the effects of C-terminal carboxylmethylation on RAB (zeige HRB Antikörper) GTPases and provide a rationale for targeting ICMT (zeige ICMT Antikörper) in the treatment of metastatic cancer

  2. The results contradict the model of feedback activation of Rab5 (zeige RAB5A Antikörper) and instead indicate that Rbpt5 is recruited by both Rabex5 (zeige RABGEF1 Antikörper) recognizing ubiquitylated cargo and by Rab4 to activate Rab5 (zeige RAB5A Antikörper) in a feed-forward manner.

  3. Rab4 expression is up-regulated by laminar shear stress, which contributed to improved vascular endothelial cell autophagy and function.

  4. Together the findings indicate that Arl1 links Rab4-dependent formation of endosomal sorting domains with downstream assembly of adaptor protein complexes that constitute the endosomal sorting machinery.

  5. HRES-1/Rab4 regulates autophagy through promoting the formation of LC3 (zeige MAP1LC3A Antikörper)(+) autophagosomes and the preservation of mitochondria.

  6. Data indicate that Rab4 regulates ether-a-go-go-related (zeige KCNH2 Antikörper) gene (hERG (zeige KCNH2 Antikörper)) channel density via neural precursor cell-expressed developmentally down-regulated protein 4 (zeige NEDD4 Antikörper)-2 (Nedd4-2 (zeige NEDD4L Antikörper)).

  7. our findings suggest an evolutionarily conserved function of HDPTP (zeige PTPN23 Antikörper)-Rab4 in the regulation of endocytic trafficking, cell adhesion and migration.

  8. TBC1D16 (zeige TBC1D16 Antikörper) is a GTPase activating protein (zeige RASA1 Antikörper) for Rab4A that regulates transferrin receptor recycling and EGFR (zeige EGFR Antikörper) trafficking and signaling.

  9. Upregulated expression of rab4, rab5 (zeige RAB5A Antikörper), rab7 (zeige RAB7B Antikörper) and rab27 (zeige RAB27A Antikörper) correlates with antemortem measures of cognitive decline in individuals with mild cognitive impairment and Alzheimer disease.

  10. Thus down- or up-regulation of Rab4A expression or Rab4A function triggered inhibition or increase of procathepsin L secretion respectively.

Mouse (Murine) RAB4A, Member RAS Oncogene Family (RAB4A) Interaktionspartner

  1. Insulin (zeige INS Antikörper)-dependent Rab4a redistribution, probably reflecting stimulation of vesicle-mediated transport, is inhibited in adipocytes subjected to differentiation in the presence of IL-6 (zeige IL6 Antikörper), IL-8 (zeige IL8 Antikörper), or IL-15 (zeige IL15 Antikörper).

  2. Reduced Akt2 (zeige AKT2 Antikörper) leads to up-regulation of Rab4a expression in cardiomyocytes in a cell-autonomous fashion that may involve activation of PPARalpha (zeige PPARA Antikörper).

  3. insulin (zeige INS Antikörper) signaling stimulates Rab4 activity, the association of Rab4 with kinesin, the interaction of KIF3 (zeige KIF3A Antikörper) with microtubules and this process is mediated by insulin (zeige INS Antikörper)-induced PI3-kinase (zeige PIK3CA Antikörper)-dependent PKC (zeige PKC Antikörper)-lambda activation and participates in GLUT4 (zeige SLC2A4 Antikörper) exocytosis

  4. p85alpha protein may play a role in the down-regulation of activated receptors through its temporal control of the GTPase (zeige RACGAP1 Antikörper) cycles of Rab5 (zeige RAB5A Antikörper) and Rab4

  5. Rab4 is a rate-limiting factor for the recycling of endogenous beta-AR; and augmentation of Rab4-mediated traffic enhances beta-AR function in cardiac myocytes

  6. Rabip4s, possibly via their interaction with Rab4, regulate integrin trafficking and are involved in the migration of NIH 3T3 fibroblasts

  7. Sorting of PDGF (zeige PDGFA Antikörper) beta-receptors on early endosomes is regulated by sequential activation of PKCalpha (zeige PKCa Antikörper) and Rab4a and that this sorting step could constitute a point of cross-talk with other receptors.

Cow (Bovine) RAB4A, Member RAS Oncogene Family (RAB4A) Interaktionspartner

  1. Receptor recycling is mediated by AP-1 (zeige JUN Antikörper)/clathrin-coated vesicles and regulated by rab4 and rabaptin-5 (zeige RABEP1 Antikörper)/rabex-5 (zeige RABGEF1 Antikörper).

RAB4A, Member RAS Oncogene Family (RAB4A) Antigen-Profil

Protein Überblick

This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.

Genbezeichner und Symbole assoziert mit RAB4A

  • RAB4A, member RAS oncogene family (rab4a) Antikörper
  • RAB4a, member RAS oncogene family (rab4a) Antikörper
  • RAB4A, member RAS oncogene family (RAB4A) Antikörper
  • RAB4A, member RAS oncogene family (LOC100341137) Antikörper
  • RAB4A, member RAS oncogene family (Rab4a) Antikörper
  • AI848268 Antikörper
  • fc93b03 Antikörper
  • HRES-1/RAB4 Antikörper
  • MGC52945 Antikörper
  • Rab4 Antikörper
  • RAB4A Antikörper
  • wu:fc93b03 Antikörper

Bezeichner auf Proteinebene für RAB4A

RAB4A, member RAS oncogene family , ras-related protein Rab-4A , Ras-related small GTP binding protein 4

GENE ID SPEZIES
380363 Xenopus laevis
403031 Danio rerio
421532 Gallus gallus
479210 Canis lupus familiaris
100302066 Ovis aries
100341137 Oryctolagus cuniculus
5867 Homo sapiens
19341 Mus musculus
25532 Rattus norvegicus
615849 Bos taurus
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