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RAB25, Member RAS Oncogene Family Proteine (RAB25)

RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Zusätzlich bieten wir Ihnen RAB25 Antikörper (70) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RAB25 57111 P57735
RAB25 53868 Q9WTL2
Ratte RAB25 RAB25 310632  
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Showing 7 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.397,30 €
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Hefe Kaninchen His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.397,30 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.397,30 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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RAB25 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu RAB25, Member RAS Oncogene Family (RAB25) Interaktionspartnern

Human RAB25, Member RAS Oncogene Family (RAB25) Interaktionspartner

  1. Promoter methylation results in downregulation of RAB25 expression in oropharyngeal squamous cell carcinoma. Decreased Rsb25 expression is associated with lymph node metastasis.

  2. Rab25 may act as a tumor promoter.

  3. Rab25 was upregulated in hepatocellular carcinoma tissues and cells compared with normal liver tissues and cell lines. Rab25 overexpression correlated with advanced tumor stage and nodal metastasis.Rab25 depletion blocked cell growth rate, inhibited colony formation, downregulated AKT (zeige AKT1 Proteine) phosphorylation, inhibited the Wnt (zeige WNT2 Proteine) signaling pathway and its target genes, and negatively regulated the invading ability of HCC (zeige FAM126A Proteine) cells.

  4. Data show that both rab G-Protein RAB25 and RNA-binding protein ESRP1 were suppressed by transcription factor ZEB1, which was in turn regulated via epigenetic mechanisms.

  5. Rab25 expression is a potential prognostic index for advanced NSCLC patients and its inhibition may improve chemosensitization in NSCLC treatment.

  6. These results showed that high levels of Rab25 expression were significantly correlated with renal cell carcinoma (zeige MOK Proteine) invasion classification (P < 0.01), lymph-node metastasis (P < 0.001), and pathological stage (P < 0.01).

  7. High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma.

  8. the crystal structure of Rab25 in complex with the C-terminal region of FIP2 (zeige OPTN Proteine), which consists of a central dimeric FIP2 (zeige OPTN Proteine) coiled-coil that mediates a heterotetrameric Rab25-(FIP2 (zeige OPTN Proteine))2-Rab25 complex.

  9. Overexpression of Rab25 contributes to metastasis of bladder cancer through induction of epithelial-mesenchymal transition and activation of Akt (zeige AKT1 Proteine)/GSK-3beta/Snail (zeige SNAI1 Proteine) signaling.

  10. These findings suggest that Rab25 plays an important role in tumor migration and metastasis, and that understanding its function may lead to the development of new strategies to prevent metastasis in oral cancer patients.

Mouse (Murine) RAB25, Member RAS Oncogene Family (RAB25) Interaktionspartner

  1. a Grhl2 (zeige GRHL2 Proteine)/Ovol2 (zeige OVOL2 Proteine) network controls Cldn4 (zeige CLDN4 Proteine) and Rab25 expression that facilitates lumen expansion and barrier formation in subtypes of renal epithelia

  2. tight regulation of CCN3 (zeige NOV Proteine) expression is necessary for normal cortical neuronal connectivity during development, and RAB25 negatively regulates neuronal differentiation as a downstream effector of CCN3 (zeige NOV Proteine)

  3. the results indicate that Grhl2 (zeige GRHL2 Proteine) regulates epithelial morphogenesis through transcriptional up-regulation of Cldn3 (zeige CLDN3 Proteine) and Cldn4 (zeige CLDN4 Proteine), as well as of Rab25, which increases the Cldn4 (zeige CLDN4 Proteine) protein and its localization at TJs

  4. Rab25 may function as a tumor suppressor in intestinal epithelial cells through regulation of protein trafficking to the cell surface.

RAB25 Protein Überblick

Protein Überblick

RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007

Genbezeichner und Symbole assoziert mit RAB25

  • RAB25, member RAS oncogene family (rab25)
  • RAB25, member RAS oncogene family (RAB25)
  • RAB25, member RAS oncogene family a (rab25a)
  • RAB25 (LOC100152692)
  • RAB25, member RAS oncogene family (Rab25)
  • AV012978 Protein
  • CATX-8 Protein
  • MGC79587 Protein
  • MGC84182 Protein
  • RAB11C Protein
  • rab25 Protein
  • si:dkeyp-84f11.7 Protein
  • zgc:101648 Protein

Bezeichner auf Proteinebene für RAB25

RAB25, member RAS oncogene family , ras-related protein Rab-25 , Ras-related protein Rab-25 , small GTP-binding protein

GENE ID SPEZIES
444652 Xenopus laevis
457382 Pan troglodytes
493286 Xenopus (Silurana) tropicalis
494098 Danio rerio
718131 Macaca mulatta
100286660 Salmo salar
100152692 Sus scrofa
57111 Homo sapiens
506482 Bos taurus
53868 Mus musculus
310632 Rattus norvegicus
490418 Canis lupus familiaris
100009059 Oryctolagus cuniculus
100858582 Gallus gallus
101084416 Felis catus
101123339 Ovis aries
100720999 Cavia porcellus
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