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RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Zusätzlich bieten wir Ihnen RAB25 Antikörper (88) und RAB25 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
The results from this analysis indicated that Rab11a (zeige RAB11A ELISA Kits), Rab11c(Rab25) and Rab14 (zeige RAB14 ELISA Kits) were expressed in a wide range of cell lines, including the human placental trophoblastic BeWo cell line.
Data show that Rab25 is responsible for RIN1-induced EGFR signaling and tumor malignancy in clear cell renal cell carcinoma cell.
Promoter methylation results in downregulation of RAB25 expression in oropharyngeal squamous cell carcinoma. Decreased Rsb25 expression is associated with lymph node metastasis.
Rab25 may act as a tumor promoter.
Rab25 was upregulated in hepatocellular carcinoma tissues and cells compared with normal liver tissues and cell lines. Rab25 overexpression correlated with advanced tumor stage and nodal metastasis.Rab25 depletion blocked cell growth rate, inhibited colony formation, downregulated AKT (zeige AKT1 ELISA Kits) phosphorylation, inhibited the Wnt (zeige WNT2 ELISA Kits) signaling pathway and its target genes, and negatively regulated the invading ability of HCC (zeige FAM126A ELISA Kits) cells.
Data show that both rab (zeige HRB ELISA Kits) G-Protein RAB25 and RNA-binding protein (zeige PTBP1 ELISA Kits) ESRP1 (zeige ESRP1 ELISA Kits) were suppressed by transcription factor ZEB1 (zeige ZEB1 ELISA Kits), which was in turn regulated via epigenetic mechanisms.
Rab25 expression is a potential prognostic index for advanced NSCLC patients and its inhibition may improve chemosensitization in NSCLC treatment.
These results showed that high levels of Rab25 expression were significantly correlated with renal cell carcinoma invasion classification (P < 0.01), lymph-node metastasis (P < 0.001), and pathological stage (P < 0.01).
High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma.
the crystal structure of Rab25 in complex with the C-terminal region of FIP2 (zeige OPTN ELISA Kits), which consists of a central dimeric FIP2 (zeige OPTN ELISA Kits) coiled-coil that mediates a heterotetrameric Rab25-(FIP2 (zeige OPTN ELISA Kits))2-Rab25 complex.
a Grhl2 (zeige GRHL2 ELISA Kits)/Ovol2 network controls Cldn4 (zeige CLDN4 ELISA Kits) and Rab25 expression that facilitates lumen expansion and barrier formation in subtypes of renal epithelia
tight regulation of CCN3 (zeige NOV ELISA Kits) expression is necessary for normal cortical neuronal connectivity during development, and RAB25 negatively regulates neuronal differentiation as a downstream effector of CCN3 (zeige NOV ELISA Kits)
the results indicate that Grhl2 (zeige GRHL2 ELISA Kits) regulates epithelial morphogenesis through transcriptional up-regulation of Cldn3 (zeige CLDN3 ELISA Kits) and Cldn4 (zeige CLDN4 ELISA Kits), as well as of Rab25, which increases the Cldn4 (zeige CLDN4 ELISA Kits) protein and its localization at TJs
Rab25 may function as a tumor suppressor in intestinal epithelial cells through regulation of protein trafficking to the cell surface.
RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007
RAB25, member RAS oncogene family
, ras-related protein Rab-25
, Ras-related protein Rab-25
, small GTP-binding protein