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RAB21, Member RAS Oncogene Family Proteine (RAB21)

RAB21 belongs to the RAB family of small GTP-binding proteins that regulate intracellular vesicle targeting (Opdam et al., 2000 [PubMed 10887961]).[supplied by OMIM, Nov 2008].. Zusätzlich bieten wir Ihnen RAB21 Antikörper (70) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
RAB21 23011 Q9UL25
RAB21 216344 P35282
Ratte RAB21 RAB21 299799 Q6AXT5
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Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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HOST_Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 11 bis 15 Tage
387,62 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.420,00 €
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.423,50 €
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Hefe Geodia cydonium His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.453,17 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
455,10 €
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Human Unkonjugiert   2 μg Anmelden zum Anzeigen 10 bis 11 Tage
186,70 €
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RAB21 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Am meisten referenzierte RAB21 Proteine

  1. Human RAB21 Protein expressed in Escherichia coli (E. coli) - ABIN667873 : Pellinen, Tuomi, Arjonen, Wolf, Edgren, Meyer, Grosse, Kitzing, Rantala, Kallioniemi, Fässler, Kallio, Ivaska: Integrin trafficking regulated by Rab21 is necessary for cytokinesis. in Developmental cell 2008 (PubMed)
    Zeige alle 2 Referenzen für ABIN667873

Weitere Proteine zu RAB21, Member RAS Oncogene Family (RAB21) Interaktionspartnern

Human RAB21, Member RAS Oncogene Family (RAB21) Interaktionspartner

  1. Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 (zeige VAMP8 Proteine) to promote autophagosome-lysosome fusion.

  2. High RAB21 expression is associated with glioma.

  3. Taken together, these data suggest that Rab21 plays a negative role in the EGF (zeige EGF Proteine)-mediated MAPK (zeige MAPK1 Proteine) signaling pathway. Overexpression of Rab21 attenuated EGF (zeige EGF Proteine)-mediated mitogen-activated protein kinase (zeige MAPK1 Proteine) (MAPK (zeige MAPK1 Proteine)) signaling by inducing EGFR (zeige EGFR Proteine) degradation.

  4. Rab21 (and Rab5 (zeige RAB5A Proteine)) associate with the cytoplasmic domains of alpha-integrin chains, and their expression influences the endo/exocytic traffic of integrins. This function of Rab21 is dependent on its GTP (zeige AK3 Proteine)/GDP cycle and proper membrane targeting

  5. Results show that targeted trafficking of integrins to and from the cleavage furrow is required for successful cytokinesis, and that this is regulated by Rab21.

  6. show that TI-VAMP (zeige VAMP7 Proteine) interacts with the Vps9 domain and ankyrin-repeat-containing protein Varp (zeige ANKRD27 Proteine), a guanine nucleotide exchange factor (zeige RASGRF1 Proteine) of the small GTPase (zeige RACGAP1 Proteine) Rab21, through a specific domain herein called the interacting domain.

Mouse (Murine) RAB21, Member RAS Oncogene Family (RAB21) Interaktionspartner

  1. this novel finding that Rab21 regulates SSTR3 (zeige SSTR3 Proteine) trafficking suggests that Rab21 may play a role in trafficking of other GPCRs.

  2. Mechanistically, p120RasGAP (zeige RASA1 Proteine) interacted with the cytoplasmic domain of integrin alpha-subunits via its GAP domain and competed with Rab21 for binding to endocytosed integrins.

  3. data indicate that Rab21 is a transient component of early and intermediate stages of macropinocytosis, and probably functions in macropinosome maturation before fusing with lysosomal compartments

RAB21 Protein Überblick

Protein Überblick

RAB21 belongs to the RAB family of small GTP-binding proteins that regulate intracellular vesicle targeting (Opdam et al., 2000

Genbezeichner und Symbole assoziert mit RAB21

  • RAB21, member RAS oncogene family (RAB21)
  • RAB21, member RAS oncogene family (rab21)
  • RAB21, member RAS oncogene family (LOC100344142)
  • RAB21, member RAS oncogene family (Rab21)
  • 9630024B22 Protein
  • MGC68816 Protein
  • RAB21 Protein

Bezeichner auf Proteinebene für RAB21

ras-related protein Rab-21 , RAB21, member RAS oncogene family , rab-12

GENE ID SPEZIES
100302077 Ovis aries
398907 Xenopus laevis
467069 Pan troglodytes
549073 Xenopus (Silurana) tropicalis
100344142 Oryctolagus cuniculus
23011 Homo sapiens
771383 Gallus gallus
507488 Bos taurus
216344 Mus musculus
299799 Rattus norvegicus
100683312 Canis lupus familiaris
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