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QDPR encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. Zusätzlich bieten wir Ihnen Quinoid Dihydropteridine Reductase Antikörper (45) und Quinoid Dihydropteridine Reductase Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.
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wide alterations in folate-associated metabolism in the Qdpr(-/-) mice
JP1 (zeige JPH1 ELISA Kits) and JP2 (zeige JPH2 ELISA Kits) can facilitate the assembly of DHPR with other proteins of the excitation-contraction coupling machinery
voltage dependence of DHPR-triggered Ca(2 (zeige CA2 ELISA Kits)+) release flux was left-shifted by approximately 8 mV by mutation in RyR1 (zeige RYR1 ELISA Kits) (Y522S)
The allele frequencies for the QDPR c.68G > A(0.3%) polymorphism is not a major cause of Parkinson's disease in the Maltese.
The mutation spectrum of the QDPR gene is different in the Chinese population. Most mutations are related to severe phenotype.
Report suggests that serum prolactin (zeige PRL ELISA Kits) levels can be a good biomarker for optimal dosage of hydroxylated precursors in long-term treatment monitoring for DHPR-deficient patients.
the electrostatic regulatory interaction between the SPRY2 (zeige SPRY2 ELISA Kits) F loop residues (that bind to imperatoxin A) and the ASI (zeige ARSI ELISA Kits)/basic residues of RyR1 (zeige RYR1 ELISA Kits) does not influence bi-directional DHPR-RyR1 (zeige RYR1 ELISA Kits) signaling during skeletal EC coupling
less than 30 microM H2O2 increase DHPR activities, whereas levels greater than 30 microM H2O2 deactivate the enzyme based on the oxidation of Met146 and Met151 in the sequence, consequently leading to disruption of the NADH-dependent enzyme active site.
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
, quinoid dihydropteridine reductase
, Dihydropteridine reductase
, 6,7-dihydropteridine reductase
, short chain dehydrogenase/reductase family 33C, member 1