anti-Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) Antikörper

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. Zusätzlich bieten wir Ihnen PDHA1 Kits (16) und PDHA1 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDHA1 5160 P08559
PDHA1 29554  
PDHA1 18597 P35486
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Top anti-PDHA1 Antikörper auf antikoerper-online.de

Showing 10 out of 151 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PDHA1 Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PDHA1 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate <b>Sample type</b>:Huh7 HepG2 (50ug)<br><b>Primary Antibody Dilution:</b> 1:500<br><b>Image Submitted by:</b> Partha Kasturi<br>University of Kansas Medical Center 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IP, WB Western Blot: Pyruvate Dehydrogenase E1-alpha subunit [p Ser293] Antibody [ABIN4099989] - Detection of PDHE1 alpha [S293] in an in vitro autophosphorylation of PDH complex in response to different stimulants: (-) none, H202-hydrogen peroxide, AR-anhydroretinol, Rol-retinol, RA-retinoic acid, PMA, Lipid-PKC lipid activator. -Photo courtesy of Dr. Beatrice Hoyos, Memorial Sloan-Kettering Cancer Center. Immunocytochemistry/Immunofluorescence: Pyruvate Dehydrogenase E1-alpha subunit [p Ser293] Antibody [ABIN4099989] - Pyruvate Dehydrogenase E1-alpha subunit [p Ser293] antibody (1:250) was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.05 mL Anmelden zum Anzeigen 2 bis 4 Tage
361,00 €
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Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of PDHA1 Antibody (Center) in Hela cell line lysates (35ug/lane). PDHA1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Rind (Kuh) Kaninchen Unkonjugiert IP, IHC, WB Immunohistochemical analysis of PDHA1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of PDHA1 expression in HepG2 (A), HUVEC (B), HeLa (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Kaninchen Unkonjugiert WB Western blot analysis of PDHA1 Antibody (Center) (ABIN653604) in Hela cell line lysates (35 µg/lane). PDHA1 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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Human Kaninchen Unkonjugiert WB PDHA1 Antibody (ABIN653605) western blot analysis in HepG2 cell line lysates (35 µg/lane).This demonstrates the PDHA1 antibody detected the PDHA1 protein (arrow). Western blot analysis of PDHA1 (arrow) using rabbit polyclonal PDHA1 Antibody (ABIN653605). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PDHA1 gene. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
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Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat testis labeled with Anti phospho-PDHA1(Ser293) Polyclonal Antibody (ABIN752878), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
326,42 €
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PDHA1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-PDHA1 Antikörper

  1. Human Polyclonal PDHA1 Primary Antibody für ICC, IF - ABIN409998 : Acin-Perez, Hoyos, Zhao, Vinogradov, Fischman, Harris, Leitges, Wongsiriroj, Blaner, Manfredi, Hammerling: Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 (PubMed)
    Show all 23 Pubmed References

  2. Polyclonal PDHA1 Primary Antibody für WB - ABIN540348 : McFate, Mohyeldin, Lu, Thakar, Henriques, Halim, Wu, Schell, Tsang, Teahan, Zhou, Califano, Jeoung, Harris, Verma: Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. in The Journal of biological chemistry 2008 (PubMed)

Weitere Antikörper gegen PDHA1 Interaktionspartner

Human Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) Interaktionspartner

  1. The report PDHA1 as a new component of brainstem-type Lewy bodies in idiopathic PD, DLB and PARK14, the level of PDHA1 protein being significantly decreased in the putamen and substantia nigra of patients with idiopathic Parkinson's disease .

  2. Findings show that serine-threonine-tyrosine kinase 1 (NOK (zeige STYK1 Antikörper)) mediates glycolysis and nuclear pyruvate dehydrogenase (zeige PDP Antikörper) complex (PDC (zeige PNKD Antikörper)) associated histone acetylation.

  3. The association of mitochondrial microphthalmia-associated transcription factor (MITF (zeige MITF Antikörper)) with pyruvate dehydrogenase (PDH (zeige PDP Antikörper)) emerges as an important regulator of mast cell function. Our findings indicate that PDH (zeige PDP Antikörper) could arise as a new target for the manipulation of allergic diseases.

  4. our results show that negative PDHA1 gene expressionis associated with significantly higher cell stemness in prostate cancer cells and reduced protein expression of this gene is associated with shorter clinical outcome in prostate cancers.

  5. oncoprotein HBXIP (zeige HBXIP Antikörper) enhances glucose metabolism reprogramming through suppressing SCO2 (zeige SCO2 Antikörper) and PDHA1 in breast cancer

  6. MPO (zeige MPO Antikörper) and BPI (zeige BPI Antikörper) in CD4 (zeige CD4 Antikörper)(+)T-lymphocytes, and PDHA1 and MRPL42 (zeige MRPL42 Antikörper) in CD8 (zeige CD8A Antikörper)(+) T-lymphocytes might be used as specific biomarkers of severe asthma progression.

  7. Phosphorylation at distinct serine and tyrosine residues inhibits PDHA1 through distinct mechanisms to impact active site accessibility.

  8. High HK2 (zeige HK2 Antikörper) expression combined with low phosphorylated PDHA1 expression in the invasive front lesions of colorectal tumors is predictive of tumor aggressiveness and survival.

  9. In the presence of PPARbeta (zeige PPARD Antikörper)/delta, Vpr induced a 3.3-fold increase in PPAR (zeige PPARA Antikörper) response element-driven transcriptional activity, a 1.9-fold increase in PDK4 (zeige PDK4 Antikörper) protein expression, and a 1.6-fold increase in the phosphorylated pyruvate dehydrogenase (zeige PDP Antikörper) subunit E1alpha.

  10. In this study the phenotypes of patients with PDH (zeige PDP Antikörper) deficiency have been divided into three groups of mutations.

Zebrafish Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) Interaktionspartner

  1. The study provired that pyruvate dehydrogenase (zeige PDK2 Antikörper)-deficient mutant caused the retinal drficits in zebrafish.

Mouse (Murine) Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1) Interaktionspartner

  1. Systemic Pyruvate Dehydrogenase (zeige PDP Antikörper) Deficiency is associated with Cerebral Developmental Abnormalities.

  2. The association of mitochondrial microphthalmia-associated transcription factor (MITF (zeige MITF Antikörper)) with pyruvate dehydrogenase (PDH (zeige PDP Antikörper)) emerges as an important regulator of mast cell function. Our findings indicate that PDH (zeige PDP Antikörper) could arise as a new target for the manipulation of allergic diseases.

  3. skeletal muscle IL-6 (zeige IL6 Antikörper) contributes to the regulation of PDH (zeige PDP Antikörper) at rest and during prolonged exercise.

  4. The present findings suggest that IL-6 (zeige IL6 Antikörper) contributes to regulating the PDHa activity and hence carbohydrate oxidation, but the metabolic state of the muscle seems to determine the outcome of this regulation

  5. Liver-specific pyruvate dehydrogenase (zeige PDP Antikörper) complex deficiency upregulates lipogenesis in adipose tissue and improves peripheral insulin (zeige INS Antikörper) sensitivity.

  6. PGC-1alpha (zeige PPARGC1A Antikörper) regulates PDH (zeige PDP Antikörper)-E1alpha protein content in parallel with mitochondrial oxidative proteins, but does not seem to influence PDH (zeige PDP Antikörper) regulation in mouse skeletal muscle in response to fasting and in recovery from exercise.

  7. Embryos carrying predominantly the Pdha1(deletion in exon 8, Deltaex8) allele were found to be globally delayed in development by 9.5 days postcoitus, with resorption occurring over the following several days.

PDHA1 Antigen-Profil

Protein Überblick

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PDHA1

  • pyruvate dehydrogenase (lipoamide) alpha 1 (pdha1) Antikörper
  • pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1) Antikörper
  • PdhA1 (pdhA1) Antikörper
  • pyruvate dehydrogenase E1 component subunit alpha (pdhA1) Antikörper
  • pyruvate dehydrogenase alpha subunit protein (pdhA1) Antikörper
  • pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit (pdhA1) Antikörper
  • precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit (PDHA1) Antikörper
  • pyruvate dehydrogenase (PDHA1) Antikörper
  • pyruvate dehydrogenase (lipoamide) alpha 1 (Pdha1) Antikörper
  • pyruvate dehydrogenase (lipoamide) alpha 1b (pdha1b) Antikörper
  • pyruvate dehydrogenase E1 alpha 1 (Pdha1) Antikörper
  • PDHA Antikörper
  • Pdha-1 Antikörper
  • Pdha1 Antikörper
  • PDHCE1A Antikörper
  • PHE1A Antikörper
  • wu:fp73b04 Antikörper
  • zgc:92705 Antikörper

Bezeichner auf Proteinebene für PDHA1

pyruvate dehydrogenase E1 alpha 1 , pyruvate dehydrogenase (lipoamide) alpha 1 , PdhA1 , pyruvate dehydrogenase alpha subunit , pyruvate dehydrogenase E1 component subunit alpha , pyruvate dehydrogenase alpha subunit protein , pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit , precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit , pyruvate dehydrogenase , pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial , PDHE1-A type I , pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like , pyruvate dehydrogenase complex, E1-alpha polypeptide 1 , Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial , pyruvate dehydrogenase E1 component alpha subunit , pyruvate dehydrogenase E1alpha subunit , pyruvate dehydrogenase alpha 1 , fp73b04

GENE ID SPEZIES
549826 Xenopus (Silurana) tropicalis
719277 Macaca mulatta
1448416 Halobacterium sp. NRC-1
3129238 Haloarcula marismortui ATCC 43049
3893971 Rhizobium etli CFN 42
6400117 Rhizobium etli CIAT 652
7195506 Phaeodactylum tricornutum CCAP 1055/1
7369176 Agrobacterium radiobacter K84
7450426 Thalassiosira pseudonana CCMP1335
100174745 Pongo abelii
100357349 Oryctolagus cuniculus
100400144 Callithrix jacchus
100471829 Ailuropoda melanoleuca
100587584 Nomascus leucogenys
418610 Gallus gallus
5160 Homo sapiens
480858 Canis lupus familiaris
100294678 Sus scrofa
407109 Bos taurus
29554 Rattus norvegicus
465525 Pan troglodytes
436672 Danio rerio
18597 Mus musculus
Ausgewählte Anbieter für anti-PDHA1 (PDHA1) Antikörper
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