Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
PC encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. Zusätzlich bieten wir Ihnen Pyruvate Carboxylase Kits (24) und Pyruvate Carboxylase Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 80 products:
Human Polyclonal PC Primary Antibody für ICC, IF - ABIN4348764
Vastag, Koyuncu, Grady, Shenk, Rabinowitz: Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism. in PLoS pathogens 2011
Show all 5 Pubmed References
Mouse (Murine) Polyclonal PC Primary Antibody für ELISA, WB - ABIN408689
St Maurice, Reinhardt, Surinya, Attwood, Wallace, Cleland, Rayment: Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme. in Science (New York, N.Y.) 2007
Human Polyclonal PC Primary Antibody für ICC, IF - ABIN4348773
Cardaci, Zheng, MacKay, van den Broek, MacKenzie, Nixon, Stevenson, Tumanov, Bulusu, Kamphorst, Vazquez, Fleming, Schiavi, Kalna, Blyth, Strathdee, Gottlieb: Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis. in Nature cell biology 2015
TR4 (zeige NR2C2 Antikörper)-mediated enhancement of fatty acid synthesis in adipocytes requires increased expression of PC gene
Repression of pyruvate carboxylase could be interpreted as a survival tactic of repressing anabolic pathways to support a redirection of limited carbon units to catabolism rather than storage
Three GC boxes within the proximal promoter of the murine pyruvate carboxylase gene bind Sp1 (zeige SP1 Antikörper)/Sp3 (zeige SP3 Antikörper)
CREB (zeige CREB1 Antikörper) bind to -1639/-1631 cyclic AMP (zeige TMPRSS5 Antikörper) responsive element of mouse PC gene in vitro and in vivo, respectively.
PPARgamma (zeige PPARG Antikörper) binds to the functional PPAR (zeige PPARA Antikörper)-response element of the PC promoter. Impaired in vitro differentiation of white adipocytes of PPARgamma2 (zeige PPARG Antikörper) knock-out mice was also associated with a marked reduction of PC mRNA
Focuses on cloning of human pyruvate carboxylase but also studies pyruvate carboxylase levels in mouse preadipocyte differentiation.
Genomic structure of the pyruvate carboxylase gene is determined. The transcripts are highly expressed in kidney and liver, moderately expressed in heart and testis, and expressed at a low level in spleen.
Pyruvate carboxylase activates the RIG-I (zeige DDX58 Antikörper)-like receptor-mediated antiviral immune response by targeting the MAVS (zeige MAVS Antikörper) signalosome.
PC and PDH (zeige PDP Antikörper) may be an important part of cellular adaptation to the IDH1 (zeige IDH1 Antikörper) mutation and may serve as potential therapeutic targets
Eight novel mutations were identified in PC from 8 pyruvate carboxylase deficiency patients.
The activities of pyruvate carboxylase (PC) were decreased by 65% in pancreatic islets of patients with type 2 diabetes.
These data indicate that pyruvate carboxylase promoter 1 is activated by fatty acids found in serum of feed-restricted cows.
Expression of pyruvate carboxylase mRNA is part of the adaptive response to feed intake restriction
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
, pyruvate carboxykinase
, pyruvate carboxylase
, pyruvate carboxylase, mitochondrial
, PYruvate Carboxylase family member (pyc-1)
, Pyruvate carboxylase
, pyruvate decarboxylase
, pyruvic carboxylase