anti-Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) Antikörper

The product of P2RX3 belongs to the family of purinoceptors for ATP. Zusätzlich bieten wir Ihnen Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
P2RX3 81739 P49654
P2RX3 5024 P56373
P2RX3 228139 Q3UR32
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Top anti-Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Antikörper auf antikoerper-online.de

Showing 10 out of 70 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, FACS, IF, IHC (p), IP, IHC, WB Double immunofluorescence staining in cultured human bladder urothelial cells (BUCs). BUCs show cytokeratin (red areas) and P2X3 (green areas) expression Immunohistochemistry-Paraffin: P2X3/P2RX3 Antibody [ABIN250458] - DRG sections double-labeled for ASIC3 (red) and either P2X3 (green, A) or TRPV1 (green, B); double-labeled cells are yellow or orange 0.05 mL Anmelden zum Anzeigen 2 bis 4 Tage
262,00 €
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Human Meerschweinchen Unkonjugiert IHC, IHC (fro), IHC (p), WB P2X3 is a subunit in the family of ion channels activated by extracellular ATP. It was cloned from rat dorsal root ganglia. P2X3 has two putative transmembrane domains with intracellular N- and C-termini. It can form homomeric channels and heteromeric channels with other members of the family. P2X3 is expressed in nociceptive sensory neurons. Immunocytochemistry/Immunofluorescence: P2X3/P2RX3 Antibody [ABIN250462] - Staining in rat DRG. 0.05 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-P2RX3/ATP receptor Polyclonal Antibody, Unconjugated (ABIN705866) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rabbit bladder labeled with Anti-P2RX3/ATP receptor Polyclonal Antibody, Unconjugated (ABIN705866) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
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Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Heart, antibody was diluted at 1:100. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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Human Kaninchen Unkonjugiert WB P2RX3 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the P2RX3 antibody detected the P2RX3 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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P2RX3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Antikörper

  1. Rat (Rattus) Polyclonal P2RX3 Primary Antibody für IF, IHC - ABIN238884 : Park, Bae, Kim, Jo, Kim, Jung, Kim, Oh: Substance P Sensitizes P2X3 in Nociceptive Trigeminal Neurons. in Journal of dental research 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal P2RX3 Primary Antibody für ICC, FACS - ABIN250458 : Tamburro, Fredolini, Espina, Douglas, Ranganathan, Ilag, Zhou, Russo, Espina, Muto, Petricoin, Liotta, Luchini: Multifunctional core-shell nanoparticles: discovery of previously invisible biomarkers. in Journal of the American Chemical Society 2011 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal P2RX3 Primary Antibody für IHC, IHC (fro) - ABIN250462 : Kaan, Yip, Patel, Davies, Marchand, Cockayne, Nunn, Dickenson, Ford, Zhong, Malcangio, McMahon: Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. in Brain : a journal of neurology 2010 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal P2RX3 Primary Antibody für IF, IHC - ABIN239021 : Xu, Chu, Brederson, Jarvis, McGaraughty: Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats. in Journal of neuroscience research 2012 (PubMed)

Weitere Antikörper gegen Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Interaktionspartner

Human Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) Interaktionspartner

  1. P2X3 expressions in endometriosis endometrium and endometriotic lesions were significantly higher as compared with control endometrium, and positively correlated with pain.

  2. P2X3 receptor expression was up-regulated in neurons from patients with temporal lobe epilepsy.

  3. X-ray crystal structures of the human P2X3 receptor in apo (zeige C9orf3 Antikörper)/resting, agonist-bound/open-pore, agonist-bound/closed-pore/desensitized and antagonist-bound/closed states

  4. there is a relationship between the elevated expression of P2X3 receptor and P2X7 receptor (zeige P2RX7 Antikörper) in peripheral blood leukocytes and high serum epinephrine and norepinephrine levels in hyperthyroidism patients.

  5. Data show that monoclonal antibodies directed against human P2X3 (12D4) potentiated the slow inactivating current mediated by the heteromeric purinergic receptor (zeige P2RX1 Antikörper) hP2X2/3 channel.

  6. Data indicate P2X3 purinergic receptors as potential new targets for hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) therapy.

  7. Results demonstrate that the stoichiometry of the heterotrimeric hP2X2/3 receptor is not fixed, but determined by the relative availability of P2X2 (zeige P2RX2 Antikörper) and P2X3 subunits

  8. Urothelial P2X3 receptors decreased significantly in responders after Lipotoxin instillation, but not after BoNT-A injection.

  9. The results from this study demonstrate that there is a significant difference in the expression of the purinergic P2X2 (zeige P2RX2 Antikörper), P2X3 and P2X7 (zeige P2RX7 Antikörper) receptors in the different histological layers of the human urinary bladder.

  10. sensory proteins P2X3 and TRPV1 (zeige TRPV1 Antikörper) are in correlation with urothelial differentiation, while P2X5 (zeige P2RX5 Antikörper) and TRPV4 (zeige TRPV4 Antikörper) have unique expression patterns

Mouse (Murine) Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) Interaktionspartner

  1. Data suggest that the negative inhibition of P2X3R activity by the BNP (zeige BNC2 Antikörper)/NPR-A (zeige NPR1 Antikörper) pathway results in a decreased P2X3R-mediated excitability of trigeminal neurons in wildetype cultures. In familial hemiplegic migraine type-1 model cultures, however, lack of efficient P2X3Rs downregulation contributes to the neuronal hyperexcitability phenotype.

  2. P2X3 receptors on mouse trigeminal ganglion neurons are subjected to contrasting modulation by inhibitory brain natriuretic peptide (zeige BNP Antikörper) and facilitatory calcitonin gene-related peptide (zeige CALCA Antikörper) that both operate via complex intracellular signaling.

  3. mouse trigeminal neurons endogenous BNP (zeige BNC2 Antikörper) acts on NPR-A (zeige NPR1 Antikörper) receptors to determine constitutive depression of P2X3 receptor function. Tonic inhibition of P2X3 receptor activity by BNP (zeige BNC2 Antikörper)/NPR-A (zeige NPR1 Antikörper)/PKG (zeige PRKG1 Antikörper) pathways occurs via two distinct mechanisms: P2X3 serine phosphorylation and receptor redistribution to non-raft membrane compartments

  4. This study observed maltodextrin and fat preference deficits in "taste-blind" P2X2 (zeige P2RX2 Antikörper)/P2X3 knockout mice.

  5. a slow modulatory action by BNP (zeige BNC2 Antikörper) on TRPV1 (zeige TRPV1 Antikörper) and P2X3 receptors outlining the role of this peptide as a negative regulator of trigeminal sensory neuron excitability to nociceptive stimuli

  6. P2X(3)R overexpression may underlie ectopic mechanical allodynia in the whisker pad skin

  7. genetic manipulation of TRPV1 (zeige TRPV1 Antikörper) and P2X3 leads to reduction in colorectal mechanosensation peripherally and compensatory changes and/or disinhibition of other channels centrally.

  8. up-regulation of P2X3 receptors probably is already maximal and is apparently contributed by basal CGRP (zeige CALCA Antikörper) and BDNF (zeige BDNF Antikörper) levels

  9. Structure and function of P2RX3 is reviewed, and its role in treatment of pain is discussed. [Review Article]

  10. interaction between P2X3/TRPV1 and ERs expression in sensory neurons may represent a novel mechanism that can explain the sex differences in nociception observed in clinical practice.

Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3) Antigen-Profil

Protein Überblick

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Genbezeichner und Symbole assoziert mit P2RX3

  • purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3) Antikörper
  • purinergic receptor P2X, ligand-gated ion channel, 3 (P2rx3) Antikörper
  • 4930513E20Rik Antikörper
  • P2RX3 Antikörper
  • P2X3 Antikörper

Bezeichner auf Proteinebene für P2RX3

purinergic receptor P2X, ligand-gated ion channel, 3 , P2X3 purinoceptor , purinergic receptor P2X3 , ATP receptor , P2X purinoceptor 3 , P2X3 , P2X receptor, subunit 3 , purinoceptor P2X3

GENE ID SPEZIES
428856 Gallus gallus
448782 Canis lupus familiaris
530468 Bos taurus
742961 Pan troglodytes
81739 Rattus norvegicus
5024 Homo sapiens
228139 Mus musculus
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