anti-Pumilio Homolog 1 (Drosophila) (PUM1) Antikörper

PUM1 encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. Zusätzlich bieten wir Ihnen Pumilio Homolog 1 (Drosophila) Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PUM1 80912 Q80U78
PUM1 362609  
PUM1 9698 Q14671
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Top anti-Pumilio Homolog 1 (Drosophila) Antikörper auf antikoerper-online.de

Showing 10 out of 61 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p) 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Ziege Unkonjugiert GS, IP, WB Western Blot analysis of human Pumilio 1, using ABIN151726. Sample: RIPA extract (10 ug) from HeLa cells (CIP, calf intestinal phosphatase). Western Blot: PUM1 Antibody [ABIN151726] - NIH-3T3 cell lysate (50 ug loaded), probed with Pumilio-1 antibody diluted at 0.1 ug/ml. 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin-fixed and paraffin-embedded humanbrain tissue reacted with Phospho-PUM1-Y83.ctrl antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of PUM1 (arrow) using PUM1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PUM1 gene (Lane 2) 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human testis tissue reacted with PUM1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of PUM1 (arrow) using rabbit polyclonal PUM1 Antibody 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of PUM1 (arrow) using PUM1 Antibody (Y83) (ABIN391822). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PUM1 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded humanbrain tissue reacted with Phospho-PUM1-Y83.ctrl antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of PUM1 (Human N-term) (ABIN392129) in HL-60 cell line lysates (35 µg/lane). PUM1 (arrow) was detected using the purified polyclonal antibody.(2 µg/mL) Formalin-fixed and paraffin-embedded human testis tissue reacted with PUM1 Antibody (N-term) (ABIN392129), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Pumilio-1 Antibody [NBP2-20011] - Immunohistochemical analysis of paraffin-embedded H441 xenograft, using antibody at 1:100 dilution. Western Blot: Pumilio-1 Antibody [NBP2-20011] - Sample (30 ug of whole cell lysate) A: Jurkat 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of Pumilio 1 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with t Western blot analysis of Pumilio 1 expression in K562 (A), NIH3T3 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Fruchtfliege Ziege Unkonjugiert IP, WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
352,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Pumilio 1 Polyclonal Antibody, Unconjugated (ABIN1387238) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details

PUM1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,
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Rat (Rattus) ,
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Human , , ,
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Am meisten referenzierte anti-Pumilio Homolog 1 (Drosophila) Antikörper

  1. Human Polyclonal PUM1 Primary Antibody für GS, IP - ABIN151726 : Chiu, Witkowska, Hall, Santiago, Soros, Esnault, Heidmann, Greene: High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 5 Pubmed References

Weitere Antikörper gegen Pumilio Homolog 1 (Drosophila) Interaktionspartner

Mouse (Murine) Pumilio Homolog 1 (Drosophila) (PUM1) Interaktionspartner

  1. Data indicate a role for RNA-binding protein Pum1 in early embryonic development.

  2. The RNA-binding protein PUMILIO1 (PUM1) not only directly regulates ATAXIN1 (zeige ATXN1 Antikörper) but also plays an unexpectedly important role in neuronal function. Loss of Pum1 caused progressive motor dysfunction and SCA1 (zeige ATXN1 Antikörper)-like neurodegeneration with motor impairment, primarily by increasing Ataxin1 (zeige ATXN1 Antikörper) levels.

  3. Key components of the p53 (zeige TP53 Antikörper) pathway are coordinately regulated by Pumilio 1 at the posttranscriptional level, which may exemplify an RNA operon.

  4. In (zeige NME1 Antikörper)mice, puf-A expression was detected primarily in retinal ganglion and pigmented cells.

Human Pumilio Homolog 1 (Drosophila) (PUM1) Interaktionspartner

  1. A recent paper by the Mendell group identifies NORAD, a novel lncRNA that is regulated in response to DNA damage and plays a key role in maintaining genome integrity by modulating the activity the RNA binding proteins PUM2 (zeige PUM2 Antikörper) and PUM1.

  2. results reveal a novel regulatory pathway, underscoring a previously unknown and interconnected key role of PUM1/2 and FOXP1 (zeige FOXP1 Antikörper) in regulating normal hematopoietic stem/progenitor cell and leukemic cell growth.

  3. Pumilios (including PUM1 and PUM2 (zeige PUM2 Antikörper)) are RNA-binding proteins with Puf domains made up of 8 poorly conserved Puf repeats, 3 helix bundles arranged in rainbow architecture, where each repeat recognizes a single base of the RNA-binding sequence. [REVIEW]

  4. Identification of NORAD-interacting proteins revealed that this lncRNA functions as a multivalent binding platform for PUM (zeige MYOD1 Antikörper) proteins, with the capacity to sequester a significant fraction of the total cellular pool of PUM1 and PUM2 (zeige PUM2 Antikörper).Studies reveal unanticipated roles for a lncRNA and PUMILIO proteins in the maintenance of genomic stability.

  5. PUM repeats have now been identified in proteins that function in pre-rRNA processing, including human Puf-A and yeast Puf6.

  6. The promoting effect of hPuf-A in tumorigenesis might be correlated with the regulation of its associated mRNAs.

  7. MED15 (zeige MED15 Antikörper) and PUM1 proteins with coiled-coil domains are potent enhancers of polyQ-mediated ataxin-1 (zeige ATXN1 Antikörper) protein misfolding and proteotoxicity in vitro and in vivo.

  8. human Pumilio homologs Pum 1 and Pum 2 repress the translation of E2F3 by binding to the E2F3 3' untranslated region (UTR) and also enhance the activity of multiple E2F3 targeting microRNAs (miRNAs)

  9. Three distinct modes of target RNA binding by PUM1 around the fifth mRNA base were observed.

  10. Pumilio-1 (PUM1) is a ubiquitously expressed RBP (zeige RBP4 Antikörper) that was shown to interact with p27 (zeige PAK2 Antikörper)-3' UTR (zeige UTS2R Antikörper).

Pumilio Homolog 1 (Drosophila) (PUM1) Antigen-Profil

Protein Überblick

This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit PUM1

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  • pumilio homolog 1 (Drosophila) (PUM1) Antikörper
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  • si:ch211-285e16.1 Antikörper
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  • wu:fb96a08 Antikörper
  • zgc:63671 Antikörper

Bezeichner auf Proteinebene für PUM1

pumilio homolog 1 , pumilio homolog 1 (Drosophila) , pumilio-1 , pumilio 1

GENE ID SPEZIES
394176 Danio rerio
100174674 Pongo abelii
100135847 Oncorhynchus mykiss
80912 Mus musculus
419554 Gallus gallus
362609 Rattus norvegicus
9698 Homo sapiens
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