Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) Proteine (PTPN18)

The protein encoded by PTPN18 is a member of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen PTPN18 Antikörper (29) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PTPN18 26469 Q99952
PTPN18 19253 Q61152
Ratte PTPN18 PTPN18 301333  
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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PTPN18 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) Interaktionspartnern

Human Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) Interaktionspartner

  1. PTPN18 regulates HER2 (zeige ERBB2 Proteine)-mediated cellular functions through defining both its phosphorylation and ubiquitination barcodes.

  2. BDP1 has a role in negative regulation of HER2 (zeige ERBB2 Proteine) signaling

  3. novel isoform of PTPN18 based on analysis of expressed sequence tags was discovered; deletion of 4 exons in the catalytic domain of the isoform may alter enzymatic activity; 2 of the novel isoform predictions were experimentally validated through RT-PCR

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18) Interaktionspartner

  1. BDP1 has a role in negative regulation of HER2 (zeige ERBB2 Proteine) signaling

PTPN18 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PTPN18

  • protein tyrosine phosphatase, non-receptor type 18 (brain-derived) (PTPN18)
  • protein tyrosine phosphatase, non-receptor type 18 (Ptpn18)
  • BDP1 Protein
  • FLP1 Protein
  • HSCF Protein
  • PTP-HSCF Protein
  • PTP-K1 Protein
  • PTP20 Protein
  • Ptpk1 Protein

Bezeichner auf Proteinebene für PTPN18

brain-derived phosphatase , tyrosine-protein phosphatase non-receptor type 18 , FLP-1 , fetal liver phosphatase 1 , protein tyrosine phosphatase 20

GENE ID SPEZIES
26469 Homo sapiens
19253 Mus musculus
301333 Rattus norvegicus
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