anti-Protein Tyrosine Phosphatase G1 (PTPN12) Antikörper

The protein encoded by PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. Zusätzlich bieten wir Ihnen PTPN12 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTPN12 5782 Q05209
PTPN12 19248 P35831
PTPN12 117255  
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Top anti-PTPN12 Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PTPN12 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HT1080 cell lysate WB Suggested Anti-PTPN12 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: HT1080 cell lysate <br /> PTPN12 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: Ptpn12 <br /> Sample Tissue: Rat Thymus lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: PTPN12 Antibody [NBP1-87188] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunohistochemistry-Paraffin: PTPN12 Antibody [NBP1-87188] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot and Immunoprecipitation: PTPN12/PTP-PEST Antibody [ABIN253137] - Detection of Human and Mouse PTPN12/PTP-PEST by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-PTPN12/PTP-PEST antibody ABIN253137 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. PTPN12/PTPPEST was also immunoprecipitated by rabbit anti-PTPN12/PTPPEST antibodies ABIN253134, ABIN253135, and ABIN253136 which recognize upstream epitopes.  Detection: Chemiluminescence with exposure times of 30 seconds (A) and 3 seconds (B). Immunohistochemistry-Paraffin: PTPN12 Antibody [ABIN2531376] - Sample: FFPE section of human colon carcinoma. Antibody used at a dilution of 1:250. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded D54 xenograft, using PTPN12, antibody at 1:500 dilution. ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using PTPN12, antibody at 1:200 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Maus Unkonjugiert EIA, IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB PTPN12 antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: PTPN12 Antibody [NBP2-20004] - Immunohistochemical analysis of paraffin-embedded D54 xenograft, using antibody at 1:500 dilution. Western Blot: PTPN12 Antibody [NBP2-20004] - Sample (30 ug of whole cell lysate) A: HeLa 5% SDS PAGE gel, diluted at 1:5000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details

PTPN12 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
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Am meisten referenzierte anti-PTPN12 Antikörper

  1. Human Polyclonal PTPN12 Primary Antibody für ICC, IF - ABIN4348590 : Harris, Blaser, Moreno, Treloar, Gorrini, Sasaki, Mason, Knobbe, Rufini, Hallé, Elia, Wakeham, Tremblay, Melino, Done, Mak: PTPN12 promotes resistance to oxidative stress and supports tumorigenesis by regulating FOXO signaling. in Oncogene 2014 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen PTPN12 Interaktionspartner

Human Protein Tyrosine Phosphatase G1 (PTPN12) Interaktionspartner

  1. this study, with a relative large population, showed that PTPN12 eQTL (zeige EQTN Antikörper) SNP may interact with HBV mutation on HCC (zeige FAM126A Antikörper) risk.

  2. MyoVa (zeige MYO5A Antikörper)-Ca(2 (zeige CA2 Antikörper)+) channel interactions are required for proper long-range axon growth in developing spinal cord in vivo.

  3. PTP-PEST regulates EphA3 (zeige EPHA3 Antikörper) activation both by affecting cytoskeletal remodelling and through its direct action as a PTP (zeige SLC25A3 Antikörper) controlling EphA3 (zeige EPHA3 Antikörper) phosphorylation.

  4. Study suggests that PTPN12 expression is a valuable prognostic biomarker for non-small cell lung cancer.

  5. PTPN12 expression decreases in human renal cell carcinoma (zeige MOK Antikörper)

  6. The decrease expression of PTPN12 might be important in conferring a more aggressive behavior in NPC (zeige NPC1 Antikörper). Thus, PTPN12 expression may be used as a novel independent prognostic biomarker for patients with NPC (zeige NPC1 Antikörper).

  7. PTPN12 is potentially a methylation-silenced TSG (zeige TWSG1 Antikörper) for breast cancer that may play an important role in breast carcinogenesis and could potentially serve as an independent prognostic factor for invasive breast cancer patients.

  8. Decreased expression of PTPN12 correlates with tumor recurrence and poor survival of patients with hepatocellular carcinoma.

  9. these data suggest that PTP-PEST affects epithelial cell motility by controlling the distribution and phosphorylation of p120 (zeige HNRNPU Antikörper) and its availability to control Rho GTPase (zeige RACGAP1 Antikörper) activity.

  10. The involvement of PTPN12 in the antioxidant response of breast cancer cells suggests that PTPN12 may represent a novel therapeutic target for this disease

Mouse (Murine) Protein Tyrosine Phosphatase G1 (PTPN12) Interaktionspartner

  1. PTPN12-deficient, ErbB2 (zeige ERBB2 Antikörper)-dependent breast cancer cells were more resistant to anoikis and had augmented migratory and invasive properties.

  2. Integrin beta 8 and PTP-PEST form protein complexes at the leading edge of migrating cells and balance patterns of Rac1 and Cdc42 (zeige CDC42 Antikörper) signaling by controlling the subcellular localization and phosphorylation status of Rho GDP dissociation inhibitor 1 (zeige ARHGDIA Antikörper).

  3. Pyk2 (zeige PTK2B Antikörper) deregulation played a pivotal role in the migration defect caused by PTPN12 deficiency.

  4. Regulation of the Src kinase-associated phosphoprotein (zeige SKAP2 Antikörper) 55 homologue by the protein tyrosine phosphatase (zeige ACP1 Antikörper) PTP-PEST in the control of cell motility.

  5. macrophage fusion is critically dependent on PTP-PEST.

  6. Overexpression of PTP-PEST substantially inhibits lipopolysaccharide (LPS (zeige TLR4 Antikörper))-induced tyrosine phosphorylation of IkappaB kinase (zeige CHUK Antikörper) (IKKbeta (zeige IKBKB Antikörper)) at Tyr188/199 in RAW264.7 cells.

  7. PTP-PEST is a key regulator of integrin-mediated functions in endothelial cells.

  8. the dephosphorylation of Pyk2 (zeige PTK2B Antikörper) requires dynamin's GTPase (zeige RACGAP1 Antikörper) activity and is mediated by the tyrosine phosphatase PTP-PEST.

  9. PTP-PEST controls Pyk2 (zeige PTK2B Antikörper) activity and is a positive regulator of secondary T cell activation.

  10. the paxillin (zeige PXN Antikörper)-PTP-PEST interaction contributes to integrin signaling

PTPN12 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Genbezeichner und Symbole assoziert mit PTPN12

  • protein tyrosine phosphatase, non-receptor type 12 (PTPN12) Antikörper
  • protein tyrosine phosphatase, non-receptor type 12 (Ptpn12) Antikörper
  • P19-PTP Antikörper
  • PTP-P19 Antikörper
  • PTP-PEST Antikörper
  • Ptpg1 Antikörper
  • RKPTP Antikörper

Bezeichner auf Proteinebene für PTPN12

protein-tyrosine phosphatase G1 , tyrosine-protein phosphatase non-receptor type 12 , MPTP-PEST , protein-tyrosine phosphatase P19

GENE ID SPEZIES
5782 Homo sapiens
19248 Mus musculus
117255 Rattus norvegicus
531877 Bos taurus
Ausgewählte Anbieter für anti-PTPN12 (PTPN12) Antikörper
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