Protein Quaking Proteine (QKI)

The protein encoded by QKI is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. Zusätzlich bieten wir Ihnen QKI Antikörper (94) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
QKI 9444 Q96PU8
QKI 19317 Q9QYS9
QKI 499022  
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Showing 8 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.784,92 €
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.784,92 €
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Hefe Cat His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.784,92 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
379,93 €
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QKI Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Protein Quaking (QKI) Interaktionspartnern

Human Protein Quaking (QKI) Interaktionspartner

  1. QKI underexpression is associated with glioma.

  2. Our results demonstrate that miR (zeige MLXIP Proteine)-143-3p acts as a tumor-suppressor by targeting QKI-5 in ESCC, suggesting that miR (zeige MLXIP Proteine)-143-3p is a potential therapy for the treatment of ESCC.

  3. Methylation of the QKI promoter and concomitant reduced expression of QKI mRNA may be important for CRC (zeige CALR Proteine) initiation and progression.

  4. quaking is essential in maintaining endothelial barrier function.

  5. QKI-7 recruits PAPD4 (zeige PAPD4 Proteine) to regulate post-transcriptional polyadenylation of target mRNAs.

  6. QKI has a role in posttranscriptionally guiding macrophage identity and function.

  7. MYB (zeige MYB Proteine)-QKI rearrangements promote tumorigenesis through three mechanisms: MYB (zeige MYB Proteine) activation by truncation, enhancer translocation driving aberrant MYB (zeige MYB Proteine)-QKI expression and hemizygous loss of the tumor suppressor QKI

  8. Data implicate QKI in the pathophysiology of inflammation and leukemoogenesis where miR (zeige MLXIP Proteine)-155 is involved.

  9. miR (zeige MLXIP Proteine)-155 regulates the cell cycle and invasion ability of colon cancer cells via the modulation of QKI expression

  10. miR (zeige MLXIP Proteine)-29a promotes scavenger receptor A expression by targeting QKI during monocyte-macrophage differentiation.

Cow (Bovine) Protein Quaking (QKI) Interaktionspartner

  1. Complementary DNA (cDNA) for bovine quaking gene (Bqk), equine quaking gene (Eqk) and porcine quaking gene (Pqk), which are homologous to mouse quaking gene (qkI), were isolated, and their nucleotide sequences were determined.

Pig (Porcine) Protein Quaking (QKI) Interaktionspartner

  1. miR (zeige MYLIP Proteine)-499 was negatively correlated to the expression of QKI in testicular tissue.

Mouse (Murine) Protein Quaking (QKI) Interaktionspartner

  1. QKI is involved in multiple aspects of oligodendroglial development. QKI disruption can impact the cell fate of oligodendrocyte precursor cells, their migration and differentiation, and ultimately myelination in the cerebellum.

  2. Data indicate a central role of microRNA miR-214 in embryonic stem cells (ESCs) - vascular smooth muscle cells (VSMCs) differentiation, and identified quaking (QKI) as a functional modulating target in miR-214 mediated VSMCs differentiation.

  3. QKI was strongly expressed by Muller glial cells in both the developing and adult retina. Neuronal expression was uniformly weak in the adult. QKI-5 was the predominantly expressed isoform in the adult retina.

  4. QKI directly plays a crucial role in the post-transcriptional regulation and expression of Sirt2 (zeige SIRT2 Proteine) to facilitate oligodendrocyte differentiation.

  5. findings reveal a crucial role for the miR (zeige MLXIP Proteine)-214-Qki pathway in the regulation of neuronal dendritic development.

  6. we identify QKI as the long-sought regulator of Neurofascin (zeige NFASC Proteine) alternative splicing

  7. Data implicate QKI in the pathophysiology of inflammation and leukemoogenesis where miR (zeige MLXIP Proteine)-155 is involved.

  8. Study establish that the shk mutation, previously localized to chromosome 17, is a quaking (qk) allele consisting of a 105-nucleotide insertion in the qk regulatory region that decreases qk transcription

  9. These results suggested that QKI5 deficiency contributed to the overactivation of FoxO1 (zeige FOXO1 Proteine) in ob/ob animals and subsequently magnified nitrosative stress and endoplasmic reticulum stress.

  10. The study provides evidence that cytoplasmic quaking I-6 acts upstream of hnRNP F (zeige HNRNPF Proteine)/H, which forms a novel pathway to control alternative splicing in myelinating glia.

QKI Protein Überblick

Protein Überblick

The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Four transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Protein Quaking Proteine (QKI)

  • QKI, KH domain containing, RNA binding (QKI)
  • quaking (Qk)
  • 1110003F05Rik Protein
  • 1500005P18 Protein
  • BqkI Protein
  • CQKI Protein
  • Hqk Protein
  • hqkI Protein
  • l(17)-1Wis Protein
  • l17Wis1 Protein
  • PqkI Protein
  • QK Protein
  • QK1 Protein
  • QK3 Protein
  • Qki Protein
  • QKI-5 Protein

Bezeichner auf Proteinebene für Protein Quaking Proteine (QKI)

RNA binding protein HQK , homolog of mouse quaking QKI (KH domain RNA binding protein) , protein quaking , quaking homolog, KH domain RNA binding , RNA binding protein HQK-7B , quaking protein , RNA binding/signal transduction protein QkI-2 , QKI, KH domain containing, RNA binding tv1 , fqkI , QKI-5 protein , lethal, Chr 17, U Wisconsin 1 , rqkI

GENE ID SPEZIES
9444 Homo sapiens
606754 Canis lupus familiaris
493722 Bos taurus
374204 Gallus gallus
492277 Sus scrofa
493723 Felis catus
19317 Mus musculus
499022 Rattus norvegicus
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