anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Antikörper

The protein encoded by PPM1A is a member of the PP2C family of Ser/Thr protein phosphatases. Zusätzlich bieten wir Ihnen Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Proteine (18) und Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PPM1A 19042 P49443
PPM1A 5494 P35813
PPM1A 24666 P20650
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Top anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Antikörper auf antikoerper-online.de

Showing 10 out of 110 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PPM1A Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert IP, ELISA, WB Western Blot: PP2C alpha/PPM1A Antibody (p6c7) [NBP1-04333] - Mouse liver cytosol extract was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PP2Calpha(1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicates PP2Calpha(~43kDa). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$381.94
Details
Human Maus Unkonjugiert FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of HeLa cells using PPM1A mouse mAb (green) and negative control (red) . 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Maus Unkonjugiert EIA, IHC (p), IP, WB Immunoblot analysis Mouse liver cytosol extract was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PP2Calpha(1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicates PP2Calpha(~43kDa) 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Maus Kaninchen Unkonjugiert IP, ELISA, WB 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$218.90
Details
Human Kaninchen Unkonjugiert WB PPM1A Antibody (pS) (ABIN658234) western blot analysis in SK-BR-3 cell line lysates (35 µg/lane). This demonstrates the PPM1A antibody detected the PPM1A protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert IP, ELISA, WB 100 μL Anmelden zum Anzeigen 13 bis 16 Tage
$374.00
Details
Human Maus Unkonjugiert EIA, IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$566.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB Western Blot: PP2C alpha/PPM1A Antibody [NBP1-32751] - A: mouse brain. Immunohistochemistry-Paraffin: PP2C alpha/PPM1A Antibody [NBP1-32751] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details

PPM1A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Antikörper

  1. Human Monoclonal PPM1A Primary Antibody für FACS, ELISA - ABIN969556 : Sun, Yu, Dotti, Shen, Tan, Savoldo, Pass, Chu, Zhang, Lu, Fu, Lin, Yang: PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation. in Cellular signalling 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal PPM1A Primary Antibody für IP, ELISA - ABIN316118 : Juhasz, Markel, Gaur, Liu, Lu, Jiang, Wu, Antony, Wu, Melillo, Meitzler, Haines, Butcher, Roy, Doroshow: NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. in The Journal of biological chemistry 2017 (PubMed)

Weitere Antikörper gegen Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A Interaktionspartner

Mouse (Murine) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Interaktionspartner

  1. findings demonstrate a novel regulatory circuit in which STING and TBK1 (zeige TBK1 Antikörper) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A dephosphorylates STING and TBK1 (zeige TBK1 Antikörper)

  2. the studies presented here position PPM1A as a new player in the wound healing-inflammation-angiogenesis axis in mouse, reveal its crucial role in homeostasis on injury, and highlight its potential as a therapeutic mediator in pathologic conditions

  3. a nuclear envelope-localized mechanism of inactivating TGF-beta (zeige TGFB1 Antikörper) signaling in which MAN1 (zeige LEMD3 Antikörper) competes with transcription factors for binding to Smad2 (zeige SMAD2 Antikörper) and Smad3 (zeige SMAD3 Antikörper) and facilitates their dephosphorylation by PPM1A.

  4. Although a non-myristoylated mutation (G2A (zeige GPR132 Antikörper)) of PPM1A and PPM1B (zeige PPM1B Antikörper) prevented membrane association, this relocalization did not likely cause the decreased activity towards AMPKalpha (zeige GRK4 Antikörper).

  5. we found that PPM1A mRNA is synthesized at the beginning of the maturation process and remains elevated in the mature oocytes, promoting the accumulation of PPM1A protein

  6. Protein phosphatase PPM1A regulates the nuclear export of Smad2 (zeige SMAD2 Antikörper)/3 through targeting nuclear exporter RanBP3 (zeige RANBP3 Antikörper).

  7. Ppm1a, through suppressing Smad2 (zeige SMAD2 Antikörper) signaling, plays a critical role in re-epithelialization during wound healing

  8. Molecular cloning and expression analysis of MPP alpha-2, a novel transcript detected in a differential screen of pituitary libraries (MPPalpha 2)

  9. Protein phosphatase 1alpha is required for lung growth and morphogenesis.

Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Interaktionspartner

  1. establish PPM1A as a novel repressor of the SMAD3 (zeige SMAD3 Antikörper) pathway in renal fibrosis

  2. Report a tumor-suppressive function of PPM1A and an independent relationship to Smad4 (zeige SMAD4 Antikörper) in pancreatic ductal adenocarcinoma.

  3. hydrogen/deuterium exchange-mass spectrometry and molecular dynamics to characterize conformational changes in PP2Calpha between the active and inactive states

  4. In a nested case control study of ischemic stroke, there was an epigenome-wide association for cg04985020 (PPM1A; P=1.78x10(-07)) with vascular recurrence in patients treated with aspirin.

  5. findings demonstrate a novel regulatory circuit in which STING and TBK1 (zeige TBK1 Antikörper) reciprocally regulate each other to enable efficient antiviral signaling activation, and PPM1A dephosphorylates STING and TBK1 (zeige TBK1 Antikörper)

  6. The TGF-beta (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) signaling system decreases its activity through strong negative regulation. We provide evidence for a new negative feedback loop through PPM1A upregulation.

  7. Loss of PPM1A is associated with the development of tumor invasion in bladder cancer patients.

  8. PPM1A is a RelA (zeige NFkBP65 Antikörper) phosphatase that regulates NF-kappaB (zeige NFKB1 Antikörper) activity and that PPM1A has tumor suppressor-like activity.

  9. a nuclear envelope-localized mechanism of inactivating TGF-beta (zeige TGFB1 Antikörper) signaling in which MAN1 (zeige LEMD3 Antikörper) competes with transcription factors for binding to Smad2 (zeige SMAD2 Antikörper) and Smad3 (zeige SMAD3 Antikörper) and facilitates their dephosphorylation by PPM1A.

  10. phosphatase activity toward phosphopeptide substrates by PP2Calpha and Wip1 (zeige PPM1D Antikörper) requires the binding of a Mg(2 (zeige MUC7 Antikörper))+ ion to the low-affinity site.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Genbezeichner und Symbole assoziert mit PPM1A

  • protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A) Antikörper
  • protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1A (Ppm1a) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog (ppm1a.L) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent 1A (Ppm1a) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Aa (ppm1aa) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Bb (ppm1bb) Antikörper
  • 2310003C21Rik Antikörper
  • 2900017D14Rik Antikörper
  • AI427932 Antikörper
  • AU017636 Antikörper
  • fc18g04 Antikörper
  • MMPa-2 Antikörper
  • MPPa-1 Antikörper
  • pp2c-alpha Antikörper
  • Pp2c1 Antikörper
  • pp2ca Antikörper
  • pp2ca2 Antikörper
  • pp2calpha Antikörper
  • ppm1a Antikörper
  • wu:fc18g04 Antikörper
  • zgc:92329 Antikörper

Bezeichner auf Proteinebene für PPM1A

Mpp alpha , PP2C-alpha , protein phosphatase 1A , protein phosphatase 2C isoform alpha , protein phosphatase IA , protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform , IA , Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform , Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform , protein phosphatase 1A, magnesium dependent, alpha isoform , protein phosphatase 2C alpha , protein phosphatase type 2C alpha 2 , protein phosphatase 1A, magnesium dependent, alpha

GENE ID SPEZIES
100738389 Sus scrofa
19042 Mus musculus
5494 Homo sapiens
24666 Rattus norvegicus
380058 Xenopus laevis
423525 Gallus gallus
480344 Canis lupus familiaris
281994 Bos taurus
100009431 Oryctolagus cuniculus
100734826 Cavia porcellus
30704 Danio rerio
100003481 Danio rerio
Ausgewählte Anbieter für anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A) Antikörper
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