Protein Kinase N1 Proteine (PKN1)

The protein encoded by PKN1 belongs to the protein kinase C superfamily. Zusätzlich bieten wir Ihnen PKN1 Antikörper (36) und PKN1 Kits (27) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PKN1 84432 P58294
PKN1 320795 P70268
Ratte PKN1 PKN1 29355 Q63433
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Top PKN1 Proteine auf

Showing 9 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
655,24 €
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Insektenzellen Human His-GST   100 μg Anmelden zum Anzeigen 7 bis 8 Tage
1.568,00 €
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 6 bis 8 Tage
306,74 €
Insektenzellen Human GST tag   10 μg Anmelden zum Anzeigen 7 bis 9 Tage
304,76 €
HOST_Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
844,64 €

PKN1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , , ,
Mouse (Murine)

Weitere Proteine zu Protein Kinase N1 (PKN1) Interaktionspartnern

Fruit Fly (Drosophila melanogaster) Protein Kinase N1 (PKN1) Interaktionspartner

  1. polarity-induced spatiotemporal control of Rok (zeige ROCK1 Proteine) and Pkn is important for unequal cortical expansion, ensuring correct cleavage furrow positioning and the establishment of physical asymmetry.

  2. The delorean phenotype, with its associated defects in wing morphology, provides evidence of a role for PKN in adult morphogenetic processes.

  3. Drosophila protein kinase N is a negative regulator of actin-myosin activity during oogenesis.

  4. identified a requirement for Pkn in wing morphogenesis, thereby revealing the first postembryonic function for Pkn

Human Protein Kinase N1 (PKN1) Interaktionspartner

  1. PKN1 activity was up-regulated by the active RhoA (zeige RHOA Proteine) mutant (G14V) and suppressed by RhoA (zeige RHOA Proteine) T19N. PKN1 siRNA interrupted the ability of RhoA (zeige RHOA Proteine) to promote ESC proliferation and DNA synthesis. The effect of RhoA (zeige RHOA Proteine) on ESC proliferation is mediated by activation of the PKN1-cyclin D1 (zeige CCND1 Proteine) pathway in vitro.

  2. These findings demonstrate a novel function of primary cilia in controlling EG-VEGF (zeige Prok1 Proteine)-regulated trophoblast invasion and reveal the underlying molecular mechanism.

  3. miR (zeige MLXIP Proteine)-346 and miR (zeige MLXIP Proteine)-582-3p regulate EG-VEGF (zeige Prok1 Proteine)-induced trophoblast invasion through repressing MMP 2 (zeige MMP2 Proteine) and MMP 9 (zeige MMP9 Proteine), and may become novel diagnostic biomarkers or therapeutic targets for EG-VEGF (zeige Prok1 Proteine)-related obstetric disorders. (c) 2016 BioFactors, 43(2):210-219, 2017.

  4. Each follicular fluid (FF) was individually aspirated and FF/serum EG-VEGF (zeige Prok1 Proteine), inhibin-a (zeige INHA Proteine), and FF IGF-1 (zeige IGF1 Proteine) levels were evaluated. The pregnant group was characterized by increased numbers of WVFs (p = 0.044), a WVE (p = 0.022), and increased levels of FF IGF-1 (zeige IGF1 Proteine) (p = 0.001) and serum EG-VEGF (zeige Prok1 Proteine) (p = 0.03).

  5. Results show the biological effects of PROK1 (zeige Prok1 Proteine)-V67I on cell functions are similar to those of wild type, and the common variant of V67I may act as a modifier in the PROK1 (zeige Prok1 Proteine)-PROKR system through down-regulation of PROK1 (zeige Prok1 Proteine) expression.

  6. Data suggest that prokineticins (PROK1 (zeige Prok1 Proteine) and PROK2 (zeige PROK2 Proteine)) and prokineticin receptors (PROKR1 (zeige PROKR1 Proteine) and PROKR2 (zeige PROKR2 Proteine)) act as main regulators of physiological functions of ovary, uterus, placenta, and testis. [REVIEW]

  7. EG-VEGF (zeige Prok1 Proteine) and its receptor PKR1 (zeige PROKR1 Proteine) might play a role in the pathogenesis of adrenocortical tumors and could serve as prognostic markers for this rare malignant disease.

  8. The prognosis was poorer in colorectal cancers that expressed both PROK1 and VEGF relative to the cases that expressed only 1 protein, and the expression of both proteins was found to be an independent prognostic factor.

  9. TXA2 (zeige TBXA2R Proteine)-mediated neoplastic responses in prostate adenocarcinoma PC-3 (zeige PCSK1 Proteine) cells occur through a PRK1/PRK2 (zeige PKN2 Proteine)-dependent mechanism.

  10. PROK1 (zeige Prok1 Proteine) levels in follicular fluid and fertilization culture media could constitute new predictive noninvasive markers of successful embryo implantation in conventional in vitro fertilization-embryo transfer

Mouse (Murine) Protein Kinase N1 (PKN1) Interaktionspartner

  1. Mechanistically, Yersinia pseudotuberculosis YopM recruits and activates the mouse host kinases PRK1 and PRK2 (zeige PKN2 Proteine) to negatively regulate pyrin (zeige MEFV Proteine) by phosphorylation.

  2. Protein kinase N1, a cell inhibitor of Akt (zeige AKT1 Proteine) kinase, has a central role in quality control of germinal center formation

  3. PKN is activated by ischemia/reperfusion and inhibits apoptosis of cardiac myocytes, thereby protecting the heart from I/R injury.

  4. Leishmania mexicana infectivity is associated with differential expression of protein kinase C-like triggered during a cell-cell contact

  5. Pkn1 is involved in ganglioside signals that regulate TNF-alpha (zeige TNF Proteine) signaling and synthesis.

PKN1 Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Genbezeichner und Symbole assoziert mit Protein Kinase N1 Proteine (PKN1)

  • Protein kinase related to protein kinase N (Pkn)
  • protein kinase N1 (PKN1)
  • zgc:162290 (zgc:162290)
  • protein kinase N1 (pkn1)
  • prokineticin 1 (PROK1)
  • protein kinase N1 (Pkn1)
  • 3-2 Protein
  • CG2049 Protein
  • CG2055 Protein
  • CT6637 Protein
  • CT6660 Protein
  • DBK Protein
  • Dmel\\CG2049 Protein
  • dPKN Protein
  • EGVEGF Protein
  • F730027O18Rik Protein
  • l(2)06736 Protein
  • l(2)45Ca Protein
  • PAK-1 Protein
  • PAK1 Protein
  • PK1 Protein
  • Pk45C Protein
  • Pk?3 Protein
  • Pkn Protein
  • PKN-ALPHA Protein
  • PKN1 Protein
  • PRK1 Protein
  • PRK2 Protein
  • Prkcl1 Protein
  • Stk3 Protein
  • v(2)rG232 Protein

Bezeichner auf Proteinebene für Protein Kinase N1 Proteine (PKN1)

CG2049-PB , CG2049-PC , CG2049-PD , CG2049-PE , CG2049-PF , CG2049-PG , CG2049-PH , CG2049-PI , CG2049-PJ , CG2049-PK , CG2049-PL , CG2049-PM , Pkn-PB , Pkn-PC , Pkn-PD , Pkn-PE , Pkn-PF , Pkn-PG , Pkn-PH , Pkn-PI , Pkn-PJ , Pkn-PK , Pkn-PL , Pkn-PM , protein kinase N , protein kinase c related , protein kinase related to protein kinase N , protein kinase-like 45C , protein kinase N1 , serine/threonine-protein kinase N1-like , EG-VEGF , black mamba toxin-related protein , endocrine-gland-derived vascular endothelial growth factor , mambakine , prokineticin-1 , protease-activated kinase 1 , protein kinase C-like 1 , protein kinase C-like PKN , protein kinase C-related kinase 1 , protein kinase PKN-alpha , protein-kinase C-related kinase 1 , serine-threonine kinase N , serine-threonine protein kinase N , serine/threonine protein kinase N , serine/threonine-protein kinase N1 , serine/threonine kinase 3 , protein kinase PKN

35950 Drosophila melanogaster
455785 Pan troglodytes
100007897 Danio rerio
100379847 Xenopus (Silurana) tropicalis
100401855 Callithrix jacchus
84432 Homo sapiens
5585 Homo sapiens
320795 Mus musculus
29355 Rattus norvegicus
100713234 Cavia porcellus
509080 Bos taurus
101118101 Ovis aries
484903 Canis lupus familiaris
Ausgewählte Anbieter für PKN1 Proteine (PKN1)
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