Protein Interacting With Protein Kinase C, alpha 1 Proteine (PICK1)

The protein encoded by PICK1 contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). Zusätzlich bieten wir Ihnen PICK1 Antikörper (139) und PICK1 Kits (27) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PICK1 9463 Q9NRD5
PICK1 18693  
PICK1 84591 Q9EP80
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Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.003,17 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.006,67 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.010,16 €
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HOST_Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
700,95 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human GST tag   50 μg Anmelden zum Anzeigen 15 bis 16 Tage
324,76 €
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HOST_Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 7 bis 14 Tage
883,93 €
Details

PICK1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

Weitere Proteine zu Protein Interacting With Protein Kinase C, alpha 1 (PICK1) Interaktionspartnern

Mouse (Murine) Protein Interacting With Protein Kinase C, alpha 1 (PICK1) Interaktionspartner

  1. Ca(2 (zeige CA2 Proteine)+) influx through ASIC1 (zeige ACCN2 Proteine) mediates chronic hypoxia and ET-1 (zeige EDN1 Proteine)-induced NFATc3 (zeige NFATC3 Proteine) nuclear import and 2) the scaffolding protein PICK1 is necessary for NFATc3 (zeige NFATC3 Proteine) nuclear import.

  2. a dual role of PICK1 in regulating macrophage polarization

  3. This study demonstrated that d-serine provent the behavioral deficits in adult Pick1 knockout mice.

  4. PICK1 is an important regulator of P2Y6R (zeige P2RY6 Proteine) expression and microglial phagocytosis.

  5. knocking-out PICK1 gene casts the neuroprotection effect by reducing ASICs current and the calcium transients in OGD (zeige FGFR1 Proteine)-Rep neuronal cells

  6. ICA1L forms BAR-domain complexes with PICK1 and is crucial for acrosome formation in spermiogenesis.

  7. results indicate that PICK1 is a crucial regulator in glutathione homeostasis and may play important roles in oxidative stress.

  8. In cultured neurons, PICK1 deletion increases surface AMPARs and blocks Abeta42-induced reduction in surface GluA2 (zeige GRIA2 Proteine).

  9. This study demonstrated that PICK1 functions in vesicle biogenesis and is necessary to maintain normal vesicle numbers and size.

  10. C-terminal domain of ICA69 (zeige ICA1 Proteine) interacts with PICK1 and acts on trafficking of PICK1-PKCalpha (zeige PKCa Proteine) complex and cerebellar plasticity.

Human Protein Interacting With Protein Kinase C, alpha 1 (PICK1) Interaktionspartner

  1. Our results demonstrate that downregulation of PICK1 elicited by miR (zeige MLXIP Proteine)-210-3p overexpression activates the TGF-b pathway, which further promotes bone metastasis in PCa (zeige FLVCR1 Proteine), indicating that the miR (zeige MLXIP Proteine)- 210-3p/PICK1/TGF-b signalling axis plays an important role in PCa (zeige FLVCR1 Proteine) bone metastasis.

  2. This study defines a novel mechanism whereby elevated [Ca(2 (zeige CA2 Proteine)+)] induced by NMDA receptor activation modulates Ago2 (zeige EIF2C2 Proteine) and miRNA activity via PICK1. Our work suggests a Ca(2 (zeige CA2 Proteine)+)-dependent process to regulate miRNA activity in neurons in response to the induction of long-term depression.

  3. We propose that PICK1 negatively regulates neoplastic infiltration of astrocytic tumors and that manipulation of PICK1 is an attractive possibility for therapeutic intervention

  4. PICK1 domain ACT links PICK1-associated vesicles to a motility factor, likely myosin, but, contrary to previous reports, PICK1 neither binds nor inhibits Arp2 (zeige ACTR2 Proteine)/3 complex.

  5. Unlike accessory domains in other BAR domain proteins, the positioning of the PDZ domains is flexible, enabling PICK1 to perform long-range, dynamic scaffolding of membrane-associated proteins.

  6. Data indicate three principal binding modes can account for protein interacting with C-kinase 1 (PICK1) PDZ domains binding specificity.

  7. PICK1 promotes Ago2 (zeige EIF2C2 Proteine) localization at endosomal compartments in neuronal dendrites and inhibits Ago2 (zeige EIF2C2 Proteine) function in translational repression following neuronal stimulation.

  8. These data indicate that Pick1 is involved in regulating the cell-cell junction in epithelial cells.

  9. C-terminal domain of ICA69 (zeige ICA1 Proteine) interacts with PICK1 and acts on trafficking of PICK1-PKCalpha (zeige PKCa Proteine) complex and cerebellar plasticity.

  10. Family-based association study failed to observe a statistically significant association for any of the genotyped SNPs in the PICK1 gene and attention-deficit hyperactivity disorder.

PICK1 Protein Überblick

Protein Überblick

The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit PICK1

  • protein interacting with PRKCA 1 (PICK1)
  • protein interacting with C kinase 1 (Pick1)
  • protein interacting with PRKCA 1 (Pick1)
  • protein interacting with PRKCA 1 (pick1)
  • DKFZp470L2127 Protein
  • MGC131295 Protein
  • PICK Protein
  • PICK1 Protein
  • prkcabp Protein

Bezeichner auf Proteinebene für PICK1

PRKCA-binding protein , protein interacting with C kinase 1 , protein kinase C-alpha-binding protein , protein kinase C, alpha binding protein , protein that interacts with C kinase 1 , protein interacting with PRKCA 1

GENE ID SPEZIES
9463 Homo sapiens
18693 Mus musculus
84591 Rattus norvegicus
418030 Gallus gallus
533737 Bos taurus
610191 Canis lupus familiaris
734086 Xenopus (Silurana) tropicalis
735226 Xenopus laevis
100171712 Pongo abelii
100055023 Equus caballus
100158107 Sus scrofa
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