Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) ELISA Kits

PROC encodes a vitamin K-dependent plasma glycoprotein. Zusätzlich bieten wir Ihnen PROC Antikörper (34) und PROC Proteine (21) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
PROC 25268 P31394
PROC 19123 P33587
PROC 5624 P04070
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Top PROC ELISA Kits auf antikoerper-online.de

Showing 8 out of 22 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Maus 6.9 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$545.68
Details
Human 29.1 pg/mL 62.5 pg/mL - 4000 pg/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$530.53
Details
Ratte 0.078 ng/mL 1.56-100 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$1,026.67
Details
Human
  1 kit Anmelden zum Anzeigen 11 bis 12 Tage
$714.29
Details
Schwein
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
Details
Hund
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,095.60
Details
Human
  1 kit Anmelden zum Anzeigen 11 bis 12 Tage
$714.29
Details
Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
Details

Am meisten referenzierte PROC ELISA Kits

  1. Mouse (Murine) PROC ELISA Kit für Sandwich ELISA - ABIN415711 : Kawasaki, Okamoto, Kawasaki, Sata: Thrombomodulin improved liver injury, coagulopathy, and mortality in an experimental heatstroke model in mice. in Anesthesia and analgesia 2014 (PubMed)

Weitere ELISA Kits für PROC Interaktionspartner

Mouse (Murine) Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) Interaktionspartner

  1. Data show that activated protein C signals via protease activated receptors PAR2 (zeige F2RL1 ELISA Kits)/PAR3 (zeige F2RL2 ELISA Kits) to expand Treg cells, mitigating the disease in mice.

  2. insulin (zeige INS ELISA Kits) and aPC (zeige APC ELISA Kits) converge on a common spliced-X-box binding protein-1 (zeige XBP1 ELISA Kits) (sXBP1) signaling pathway to maintain endoplasmic reticulum (ER) homeostasis.

  3. loss of the convertase furin (zeige FURIN ELISA Kits) or PC5 (zeige PCSK5 ELISA Kits)/6 in hepatocytes results in a approximately 30% decrease in APC (zeige APC ELISA Kits) levels, with no significant contribution from PACE4 (zeige PCSK6 ELISA Kits). We conclude that prior convertase cleavage of protein C in hepatocytes is critical for its thrombin (zeige F2 ELISA Kits) activation.

  4. APC (zeige APC ELISA Kits) modifies pulmonary fibrosis by limiting thrombin (zeige F2 ELISA Kits)-dependent macrophage recruitment.

  5. Small interfering RNA-mediated silencing of protein C in apolipoprotein E (zeige APOE ELISA Kits)-deficient mice creates a condition that allows the occurrence of spontaneous atherothrombosis.

  6. These findings reveal a novel biological function and mechanism of the protein C pathway in which protein S and the aPC (zeige APC ELISA Kits)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (zeige APC ELISA Kits) in the context of endotoxemia and infection

  7. activated PC-EPCR-PAR1 signaling promotes hematopoietic stem cell retention in bone marrow.

  8. impaired EPCR (zeige PROCR ELISA Kits)/protein C-binding interactions not only result in procoagulant and proinflammatory effects, but also impact hematopoiesis

  9. SOD prevents thrombomodulin (zeige THBD ELISA Kits) methionine oxidation, promotes protein C activation, and protects against arterial and venous thrombosis in mice.

  10. sPLA2 (zeige PLA2G2A ELISA Kits)-V plays a thrombogenic role by impairing the ability of EPCR (zeige PROCR ELISA Kits) to promote protein C activation.

Human Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) Interaktionspartner

  1. EPCR (zeige PROCR ELISA Kits) occupancy recruits G-protein coupled receptor kinase 5 (zeige GRK5 ELISA Kits), thereby inducing beta-arrestin-2 (zeige ARRB2 ELISA Kits) biased PAR1 (zeige MARK2 ELISA Kits) signaling by both APC (zeige APC ELISA Kits) and thrombin (zeige F2 ELISA Kits). In

  2. A novel mutation of A309V in PROC was determined in a family of two patients with late onset protein C deficiency

  3. loss of the convertase furin (zeige FURIN ELISA Kits) or PC5 (zeige PCSK5 ELISA Kits)/6 in hepatocytes results in a approximately 30% decrease in APC (zeige APC ELISA Kits) levels, with no significant contribution from PACE4 (zeige PCSK6 ELISA Kits). We conclude that prior convertase cleavage of protein C in hepatocytes is critical for its thrombin (zeige F2 ELISA Kits) activation.

  4. Both probands had hereditary protein C deficiencies, for which their parents were all carriers.

  5. Variants influencing circulating protein C levels in the CELSR2 (zeige CELSR2 ELISA Kits)-PSRC1 (zeige PSRC1 ELISA Kits)-SORT1 (zeige SORT1 ELISA Kits) region may indicate a novel genetic link between lipoprotein metabolism and hemostasis.

  6. These findings suggest that the anti-inflammatory function of APC (zeige APC ELISA Kits) at therapeutic concentrations may include the inhibition of NETosis in an EPCR (zeige PROCR ELISA Kits)-, PAR3 (zeige F2RL2 ELISA Kits)-, and Mac-1 (zeige ITGAM ELISA Kits)-dependent manner, providing additional mechanistic insight into the diverse functions of neutrophils and APC (zeige APC ELISA Kits) in disease states including sepsis.

  7. Collectively, these data depict a pivotal role for AMPK (zeige PRKAA1 ELISA Kits) signaling in inhibiting ER stress responses via the activation of APC (zeige APC ELISA Kits) during MGO-induced cardiomyocyte apoptosis. Thus, APC (zeige APC ELISA Kits) may be a potential novel therapeutic target for the management of diabetic cardiovascular complications such as diabetic cardiomyopathy.

  8. An activation-resistant homozygous protein C R229W mutation was linked to perinatal intracranial bleeding and delayed onset of thrombosis.

  9. Structural and functional studies of novel heterozygous mutations in the PROC gene confirmed that the mutations were pathogenetic in two Chinese families with types I and II protein C deficiency.

  10. Study detected a statistically significant positive correlation between expanded disability status scale scores and thrombomodulin (zeige THBD ELISA Kits) levels (p<0.01) and a 10% positive correlation between expanded disability status scale scores and APC (zeige APC ELISA Kits) levels in multiple sclerosis patients

Cow (Bovine) Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) Interaktionspartner

  1. Activated protein c is a ghrelin (zeige GHRL ELISA Kits) endopeptidase.

  2. Activated protein C(APC (zeige APC ELISA Kits)) combined with protein S(PS) had significant antithrombotic effect. APC (zeige APC ELISA Kits) combined with PS prolonged clotting time. Dependence on APC (zeige APC ELISA Kits)-cofactor activity of PS for expression of anticoagulant activity by APC (zeige APC ELISA Kits).

PROC Antigen-Profil

Beschreibung des Gens

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Genbezeichner und Symbole assoziert mit PROC

  • protein C (inactivator of coagulation factors Va and VIIIa), a (proca) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (PROC) Antikörper
  • protein C (inactivator of coagulation factors Va and VIIIa) (PROC) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa S homeolog (proc.S) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (proc) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ000393) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ002754) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ003717) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ003718) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ014440) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ018032) Antikörper
  • vitamin K-dependent protein C (CpipJ_CPIJ018737) Antikörper
  • protein C, inactivator of coagulation factors Va and VIIIa (Proc) Antikörper
  • protein C (Proc) Antikörper
  • APC Antikörper
  • MGC64425 Antikörper
  • PC Antikörper
  • PROC Antikörper
  • PROC1 Antikörper
  • si:ch1073-188c16.3 Antikörper
  • THPH3 Antikörper
  • THPH4 Antikörper
  • zgc:63987 Antikörper

Bezeichner auf Proteinebene für PROC

protein C , procl , anticoagulant protein C , vitamin K-dependent protein C , protein C (inactivator of coagulation factors Va and VIIIa) , vitamin K-dependent protein C-like , autoprothrombin IIA , blood coagulation factor XIV , inactivator of coagulation factors Va, VIII , catalytic region , protein C (precursor of vitamin K-dependent serine protease)

GENE ID SPEZIES
393327 Danio rerio
395085 Gallus gallus
459593 Pan troglodytes
100302329 Ovis aries
380116 Xenopus laevis
548476 Xenopus (Silurana) tropicalis
100231143 Taeniopygia guttata
100448857 Pongo abelii
6031231 Culex quinquefasciatus
6033948 Culex quinquefasciatus
6035053 Culex quinquefasciatus
6035054 Culex quinquefasciatus
6047546 Culex quinquefasciatus
6052150 Culex quinquefasciatus
6052641 Culex quinquefasciatus
25268 Rattus norvegicus
19123 Mus musculus
5624 Homo sapiens
281428 Bos taurus
101096161 Felis catus
476104 Canis lupus familiaris
100051306 Equus caballus
396954 Sus scrofa
100009223 Oryctolagus cuniculus
699077 Macaca mulatta
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