anti-Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) Antikörper

The protein encoded by PTGER1 is a member of the G protein-coupled receptor family. Zusätzlich bieten wir Ihnen Prostaglandin E Receptor 1 (Subtype EP1), 42kDa Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTGER1 19216 P35375
PTGER1 25637 P70597
PTGER1 5731 P34995
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Top anti-Prostaglandin E Receptor 1 (Subtype EP1), 42kDa Antikörper auf antikoerper-online.de

Showing 10 out of 63 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert EIA, IHC (p) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney labeled with Anti PTGER1/EP1 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: mouse kidney lysates probed with Anti PTGER1 Polyclonal Antibody, Unconjugated (ABIN872820) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 42kD. Observed band size: 42kD 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
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Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: PTGER1 Antibody [NLS962] - Analysis of anti-PTGER1 / EP1 antibody with human kidney, renal tubules at dilution 13 ug/ml. 0.05 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Ziege Unkonjugiert IHC (p), ELISA Human Spleen (formalin-fixed, paraffin-embedded) stained with PTGER1 antibody ABIN297511 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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PTGER1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Prostaglandin E Receptor 1 (Subtype EP1), 42kDa Antikörper

  1. Human Polyclonal PTGER1 Primary Antibody für ELISA, WB - ABIN185589 : Han, Wu: Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt. in The Journal of biological chemistry 2005 (PubMed)

Weitere Antikörper gegen Prostaglandin E Receptor 1 (Subtype EP1), 42kDa Interaktionspartner

Mouse (Murine) Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) Interaktionspartner

  1. Our study identifies the EP1 signaling pathway as an important link between neuroinflammation and MMP-mediated BBB (zeige ALMS1 Antikörper) breakdown in ischemic stroke.

  2. EP1-/- mice maintain increased bone mineral density and stronger cortical and trabecular bone biomechanical properties with aging. The EP1 receptor acts to inhibit bone marrow osteoprogenitor cell differentiation and mineralization.

  3. Results indicate that EP1 receptor activation during seizures, through a protein kinase C (zeige PKC Antikörper) pathway, increases probability of kainic acid induced status epilepticus, and independently promotes hippocampal neurodegeneration and a broad inflammatory response

  4. The EP1 receptor facilitates the actions of angiotensin II, thereby suggesting that targeting of both the renin (zeige REN Antikörper)-angiotensin system and the EP1 receptor could be beneficial in diabetic nephropathy.

  5. Propose a mechanism whereby ANG II (zeige AGT Antikörper) increases COX-1 (zeige PTGS1 Antikörper)-derived PGE2 through the AT1R (zeige AGTRAP Antikörper)/PLA2 (zeige PLA2G2A Antikörper) pathway, which promotes ROS (zeige ROS1 Antikörper) production by EP1R/Nox2 (zeige CYBB Antikörper) signaling in the subfornical organ.

  6. dietary administration and direct injection of the EP1 receptor-specific antagonist, ONO-8713, effectively reduced the growth of established CT26 (zeige DDX53 Antikörper) tumors in BALB/c mice

  7. EP1 deletion protects mice from asymmetrical Parkinsonism. The PGE2 EP1 receptor is implicated in 6-OHDA-induced Parkinsonism.

  8. Data suggest that EP1 receptor blockade may be a viable target for antihypertensive therapy.

  9. data suggest that the tumor promoting/progressing effects of EP1 require the PGE2 synthesized by COX-2 (zeige COX2 Antikörper)

  10. Peripheral EP1 receptors contribute significantly to inflammation induced heat pain sensitization while evidence for a contribution to central sensitization was not obtained.

Human Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) Interaktionspartner

  1. COX-2 (zeige COX2 Antikörper) expression appears to be linked to early hepatocellular carcinoma events (initiation), while EP1 receptor expression may participate in tumor progression and predict survival

  2. Copy number variation in PTGER1 is associated with NSAIDs-induced urticaria and/or angioedema

  3. suppression of EP1 prevented RAMA-induced FasL (zeige FASL Antikörper) suppression in CLT85 cells at both the mRNA and protein levels

  4. A transient interaction between COX-2 (zeige COX2 Antikörper) and EP1 constitutes a feedback loop whereby an increase in COX-2 (zeige COX2 Antikörper) expression elevates EP1.

  5. NF-kappaB (zeige NFKB1 Antikörper) inhibitor suppressed 17-PT-PGE2-mediated FoxC2 (zeige FOXC2 Antikörper) upregulation. Immunohistochemistry showed p65 (zeige GORASP1 Antikörper), FoxC2 (zeige FOXC2 Antikörper), EP1 receptor and beta1-integrin were all highly expressed in the HCC (zeige FAM126A Antikörper) cases

  6. COX-1 (zeige COX1 Antikörper), H446K' is significantly more sensitive to downregulation by EP . Together these data suggest that distinctive ubiquitination of COX-1 (zeige COX1 Antikörper) and COX-2 (zeige COX2 Antikörper) may be responsible for their different sensitivity to EP -mediated degradation.

  7. through complex formation with D1, EP1 signaling directs the D1 receptor through G(betagamma) to be coupled to AC7 (zeige Adcy7 Antikörper).

  8. PGE2-enhanced MMP2 (zeige MMP2 Antikörper) expression is mediated through EP1 receptors and calcium signaling pathway-induced CREB (zeige CREB1 Antikörper) phosphorylation in human cholangiocarcinoma cells.

  9. Our study suggests that the PGE (zeige LIPF Antikörper) EP1 receptor regulates FAK (zeige PTK2 Antikörper) phosphorylation by activating the PKC (zeige PRRT2 Antikörper)/c-Src (zeige SRC Antikörper) and EGFR (zeige EGFR Antikörper) signal pathways, which may coordinately regulate adhesion and migration in HCC (zeige FAM126A Antikörper)

  10. PGE (zeige LIPF Antikörper)(2) -mediated NF-kappaB (zeige NFKB1 Antikörper) activation by simultaneous stimulation of EP(1) and EP(4 (zeige PTGER4 Antikörper)) receptors induces maximal IL-8 (zeige IL8 Antikörper) promoter activation and IL-8 (zeige IL8 Antikörper) mRNA and protein induction

Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.

Genbezeichner und Symbole assoziert mit PTGER1

  • prostaglandin E receptor 1 (subtype EP1), 42kDa (PTGER1) Antikörper
  • prostaglandin E receptor 1 (subtype EP1) (Ptger1) Antikörper
  • prostaglandin E2 receptor EP1 subtype-like (LOC100855637) Antikörper
  • 42kDa Antikörper
  • EP1 Antikörper
  • PTGER1 Antikörper
  • Ptgerep1 Antikörper

Bezeichner auf Proteinebene für PTGER1

prostaglandin E receptor 1 (subtype EP1), 42kDa , prostaglandin E2 receptor subtype EP1 , PGE receptor EP1 subtype , PGE2 receptor EP1 subtype , prostaglandin E2 receptor EP1 subtype , prostanoid EP1 receptor , EP1 prostanoid receptor , PGE receptor, EP1 subtype , prostaglandin E receptor EP1 subtype , prostaglandin E receptor 1, subtype EP1

GENE ID SPEZIES
747643 Pan troglodytes
100008680 Oryctolagus cuniculus
19216 Mus musculus
25637 Rattus norvegicus
5731 Homo sapiens
610774 Canis lupus familiaris
100855637 Canis lupus familiaris
Ausgewählte Anbieter für anti-Prostaglandin E Receptor 1 (Subtype EP1), 42kDa (PTGER1) Antikörper
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