Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) ELISA Kits

PCSK4 encodes a member of the subtilisin-like proprotein convertase family. Zusätzlich bieten wir Ihnen PCSK4 Antikörper (54) und PCSK4 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
PCSK4 29596 P20695
Anti-Human PCSK4 PCSK4 54760 Q6UW60
Anti-Maus PCSK4 PCSK4 18551 P29121
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Ratte 18.75 pg/mL 31.25-2000 pg/mL   96 Tests Anmelden zum Anzeigen 11 bis 15 Tage
415,71 €
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Weitere ELISA Kits für PCSK4 Interaktionspartner

Human Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) Interaktionspartner

  1. Maturation by propeptide removal occurs very inefficiently when rat or human proPCSK4 is overexpressed in HEK293 cells where it interacts with BiP.

  2. abnormal processing of IGF-II by PC4 (zeige IFRD1 ELISA Kits) may represent a previously uncharacterized mechanism involved in the pathophysiology of fetoplacental growth restriction

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) Interaktionspartner

  1. These observations indicate that non-histone chromatin-associated proteins like PC4 (zeige IFRD1 ELISA Kits) play a significant role in neuronal plasticity.

  2. Results suggest that positive cofactor 4 (Pc4 (zeige SUB1 ELISA Kits)) has an important role in inducing spontaneous somatic cell reprogramming via up-regulation of key pluripotency genes.

  3. CRES (zeige CST8 ELISA Kits) may be a regulator of PC4 (zeige IFRD1 ELISA Kits) in sperm-egg interaction and fertilization.

  4. Data suggest that the fertility defect in PCSK4 knockout mice is due, in part, to altered processing/proteolysis of ACRBP (zeige ACRBP ELISA Kits) (proacrosin/acrosin (zeige ACR ELISA Kits) binding protein sp32 (zeige ACRBP ELISA Kits)) as well as structural abnormalities in sperm heads and acrosomes.

  5. thatADAM2may be a natural substrate of sperm PCSK4 and its cleavage by the enzyme during acrosome reaction may be relevant to the fertilization process.

  6. Efficient activation and trafficking of PCSK4 requires a special environment, which presumably exists in testicular germ cells where it is highly expressed, but not in somatic cells where it is not or is barely expressed.

  7. Alterations in signal transduction and proteolytic processing during in vitro capacitation may underlie the fertilization incompetence of PCSK4-null sperm.

  8. Redox-mediated upregulation of hepatocyte iNOS (zeige NOS2 ELISA Kits) transcription requires an HNF-4alpha (zeige HNF4A ELISA Kits)-PC4 (zeige IFRD1 ELISA Kits) transcriptional complex

  9. Report recruitment of RNA polymerase II cofactor PC4 (zeige IFRD1 ELISA Kits) to DNA damage sites.

  10. PCSK4-null sperm underwent capacitation at a faster rate; they were induced to acrosome react by lower concentrations of zona pellucida; and their egg-binding ability was only half that of wild-type sperm.

PCSK4 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II.

Genbezeichner und Symbole assoziert mit PCSK4

  • proprotein convertase subtilisin/kexin type 4 (PCSK4) Antikörper
  • proprotein convertase subtilisin/kexin type 4 (pcsk4) Antikörper
  • interferon-related developmental regulator 1 (Ifrd1) Antikörper
  • proprotein convertase subtilisin/kexin type 4 (Pcsk4) Antikörper
  • SUB1 homolog (S. cerevisiae) (Sub1) Antikörper
  • AI647044 Antikörper
  • AI842364 Antikörper
  • L21221 Antikörper
  • MGC146505 Antikörper
  • NEC 3 Antikörper
  • NEC3 Antikörper
  • P9 Antikörper
  • P15 Antikörper
  • PC4 Antikörper
  • PCSK4 Antikörper
  • Rpo2tc1 Antikörper
  • SPC5 Antikörper

Bezeichner auf Proteinebene für PCSK4

proprotein convertase subtilisin/kexin type 4 , IRPR , nerve growth factor-inducible protein PC4 , KEX2-like endoprotease 3 , neuroendocrine convertase 3 , prohormone convertase 3 , NEC 3 , PC4 , RNA polymerase II transcriptional coactivator , activated RNA polymerase II transcriptional coactivator p15 , p14 , positive cofactor 4 , single-stranded DNA-binding protein p9

GENE ID SPEZIES
485083 Canis lupus familiaris
508744 Bos taurus
707567 Macaca mulatta
779814 Xenopus (Silurana) tropicalis
749996 Pan troglodytes
29596 Rattus norvegicus
54760 Homo sapiens
18551 Mus musculus
171085 Rattus norvegicus
20024 Mus musculus
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