anti-Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) Antikörper

PCSK4 encodes a member of the subtilisin-like proprotein convertase family. Zusätzlich bieten wir Ihnen PCSK4 Proteine (5) und PCSK4 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PCSK4 29596 P20695
PCSK4 54760 Q6UW60
PCSK4 18551 P29121
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Top anti-PCSK4 Antikörper auf antikoerper-online.de

Showing 10 out of 54 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PCSK4 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: OVCAR-3 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Ratte Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of PC4 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in Immunohistochemical analysis of PC4 staining in human stomach formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the a 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
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Hund Kaninchen Unkonjugiert IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$343.75
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$343.75
Details
Human Kaninchen Unkonjugiert WB PCSK4 Antibody (N-term)  western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the PCSK4 antibody detected the PCSK4 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB PCSK4 antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

PCSK4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)


Human ,
,

, , , , , , , , , , , , , , , ,
Mouse (Murine)


Weitere Antikörper gegen PCSK4 Interaktionspartner

Human Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) Interaktionspartner

  1. Maturation by propeptide removal occurs very inefficiently when rat or human proPCSK4 is overexpressed in HEK293 cells where it interacts with BiP.

  2. abnormal processing of IGF-II by PC4 (zeige IFRD1 Antikörper) may represent a previously uncharacterized mechanism involved in the pathophysiology of fetoplacental growth restriction

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) Interaktionspartner

  1. These observations indicate that non-histone chromatin-associated proteins like PC4 (zeige IFRD1 Antikörper) play a significant role in neuronal plasticity.

  2. Results suggest that positive cofactor 4 (Pc4 (zeige SUB1 Antikörper)) has an important role in inducing spontaneous somatic cell reprogramming via up-regulation of key pluripotency genes.

  3. CRES (zeige CST8 Antikörper) may be a regulator of PC4 (zeige IFRD1 Antikörper) in sperm-egg interaction and fertilization.

  4. Data suggest that the fertility defect in PCSK4 knockout mice is due, in part, to altered processing/proteolysis of ACRBP (zeige ACRBP Antikörper) (proacrosin/acrosin (zeige ACR Antikörper) binding protein sp32 (zeige ACRBP Antikörper)) as well as structural abnormalities in sperm heads and acrosomes.

  5. thatADAM2may be a natural substrate of sperm PCSK4 and its cleavage by the enzyme during acrosome reaction may be relevant to the fertilization process.

  6. Efficient activation and trafficking of PCSK4 requires a special environment, which presumably exists in testicular germ cells where it is highly expressed, but not in somatic cells where it is not or is barely expressed.

  7. Alterations in signal transduction and proteolytic processing during in vitro capacitation may underlie the fertilization incompetence of PCSK4-null sperm.

  8. PCSK4-null sperm underwent capacitation at a faster rate; they were induced to acrosome react by lower concentrations of zona pellucida; and their egg-binding ability was only half that of wild-type sperm.

  9. Redox-mediated upregulation of hepatocyte iNOS (zeige NOS2 Antikörper) transcription requires an HNF-4alpha (zeige HNF4A Antikörper)-PC4 (zeige IFRD1 Antikörper) transcriptional complex

  10. Report recruitment of RNA polymerase II cofactor PC4 (zeige IFRD1 Antikörper) to DNA damage sites.

PCSK4 Antigen-Profil

Protein Überblick

This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II.

Genbezeichner und Symbole assoziert mit PCSK4

  • proprotein convertase subtilisin/kexin type 4 (PCSK4) Antikörper
  • proprotein convertase subtilisin/kexin type 4 (pcsk4) Antikörper
  • interferon-related developmental regulator 1 (Ifrd1) Antikörper
  • proprotein convertase subtilisin/kexin type 4 (Pcsk4) Antikörper
  • SUB1 homolog (S. cerevisiae) (Sub1) Antikörper
  • AI647044 Antikörper
  • AI842364 Antikörper
  • L21221 Antikörper
  • MGC146505 Antikörper
  • NEC 3 Antikörper
  • NEC3 Antikörper
  • P9 Antikörper
  • P15 Antikörper
  • PC4 Antikörper
  • PCSK4 Antikörper
  • Rpo2tc1 Antikörper
  • SPC5 Antikörper

Bezeichner auf Proteinebene für PCSK4

proprotein convertase subtilisin/kexin type 4 , IRPR , nerve growth factor-inducible protein PC4 , KEX2-like endoprotease 3 , neuroendocrine convertase 3 , prohormone convertase 3 , NEC 3 , PC4 , RNA polymerase II transcriptional coactivator , activated RNA polymerase II transcriptional coactivator p15 , p14 , positive cofactor 4 , single-stranded DNA-binding protein p9

GENE ID SPEZIES
485083 Canis lupus familiaris
508744 Bos taurus
707567 Macaca mulatta
779814 Xenopus (Silurana) tropicalis
749996 Pan troglodytes
29596 Rattus norvegicus
54760 Homo sapiens
18551 Mus musculus
171085 Rattus norvegicus
20024 Mus musculus
Ausgewählte Anbieter für anti-PCSK4 (PCSK4) Antikörper
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