anti-Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) Antikörper

P4HA1 encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. Zusätzlich bieten wir Ihnen P4HA1 Kits (19) und P4HA1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
P4HA1 18451 Q60715
P4HA1 5033 P13674
P4HA1 64475 P54001
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Top anti-P4HA1 Antikörper auf antikoerper-online.de

Showing 10 out of 60 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN190847 (0.2µg/ml) staining of HEK293 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Ziege Unkonjugiert ELISA, IHC (p), WB Western Blot: P4HA1 Antibody [ABIN252918] - ABIN252918 (0.2µg/ml) staining of HEK293 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: P4HA1 Antibody [ABIN2529182] - Analysis of P4HA1 in HEK293 cell lysate (35ug protein in RIPA buffer) using ABIN2529182 at 0.1ug/ml. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Pferd Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Hund Ziege Unkonjugiert EIA, IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with P4HA1at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Spleen (formalin-fixed, paraffin-embedded) stained with P4HA1at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details
Hund Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 10 bis 12 Tage
$455.40
Details
Fledermaus Ziege Unkonjugiert IHC (p), ELISA, WB Human Skin (formalin-fixed, paraffin-embedded) stained with P4HA1 antibody ABIN461984 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Spleen (formalin-fixed, paraffin-embedded) stained with P4HA1 antibody ABIN461984 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Kaninchen Unkonjugiert WB P4HA1 Antibody (C-term)  western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the P4HA1 antibody detected the P4HA1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert WB Western Blot analysis of P4HA1 expression in transfected 293T cell line by P4HA1 MaxPab polyclonal antibody.<br><br>Lane 1: P4HA1 transfected lysate(58.74 KDa).<br>Lane 2: Non-transfected lysate.<br> P4HA1 MaxPab polyclonal antibody. Western Blot analysis of P4HA1 expression in A-431. 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

P4HA1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)
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Human
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Rat (Rattus)
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Am meisten referenzierte anti-P4HA1 Antikörper

  1. Human Polyclonal P4HA1 Primary Antibody für ELISA, IHC (p) - ABIN252918 : Van Duyn Graham, Sweetwyne, Pallero, Murphy-Ullrich: Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix. in The Journal of biological chemistry 2010 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal P4HA1 Primary Antibody für WB - ABIN518574 : Ma, Guo, Liu, Liu, Hu, Sun, Yu, Lammi: Proteomic changes in articular cartilage of human endemic osteoarthritis in China. in Proteomics 2011 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen P4HA1 Interaktionspartner

Mouse (Murine) Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) Interaktionspartner

  1. Overexpression of P4Ha1 increased atherosclerotic plaque size.

  2. IL-6 (zeige IL6 Antikörper) destabilizes atherosclerotic plaques by downregulating P4Halpha1 via an RAF-MEK1/2-ERK1/2 MAPK and c-Jun pathway.

  3. C-P4H alpha(I) and alpha(II (zeige GSTA3 Antikörper)) mRNA levels were increased in hypoxic mouse chondrocytes in a manner dependent on HIF-1a (zeige HIF1A Antikörper).

Human Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1) Interaktionspartner

  1. we report compound heterozygous frameshift and splice site mutations in P4HA1 that impair but not abolish C-P4H alpha(I) activity. The maternal P4HA1 exon 12 splice donor site mutation causes an internally deleted C-P4H alpha(I) predicted to completely lack catalytic activity. two nucleic acid insertion in exon 9 results in a premature stop in the exon 9 P4HA1 splice form.

  2. Findings suggest that the catalytic domain of collagen prolyl 4-hydroxylases (CP4Hs) recognizes the cis (zeige CISH Antikörper) conformation of the prolyl peptide bond.

  3. Thus, we conclude that miR (zeige MLXIP Antikörper)-30e suppresses proliferation of hepatoma cells through targeting P4HA1 mRNA.

  4. Studies indicate P4HA1 copy number gain in a subset of metastatic prostate tumors and its expression is also regulated by microRNA-124.

  5. Overexpression of miR (zeige MLXIP Antikörper)-122 markedly attenuated the expression of P4HA1 via targeting a binding site located at 3'-UTR (zeige UTS2R Antikörper) of P4HA1 mRNA

  6. Hypoxia-inducible factor 1 (HIF-1 (zeige HIF1A Antikörper)) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2 (zeige P4HA2 Antikörper), and PLOD2 (zeige PLOD2 Antikörper) expression in fibroblasts.

  7. IL-6 (zeige IL6 Antikörper) significantly downregulated P4Halpha1 expression in aortic smooth muscle cells

  8. analysis of the 2-His-1 (zeige HTN1 Antikörper)-Asp (zeige ASIP Antikörper) active-site motif in prolyl 4-hydroxylase

  9. Collagen prolyl 4-hydroxylase-alpha (I)mRNA is stabilized by interation of RNA-binding proteins hnRNP-A2/B1 (zeige HNRNPA2B1 Antikörper) with a U(16) element within the 3'-UTR (zeige UTS2R Antikörper)

  10. Results suggest that the alteration of translational efficiency by nucleolin (zeige NCL Antikörper), which occurs through a hypoxia inducible factor independent pathway, is an important step in collagen prolyl 4-hydroxylase-alpha(I) regulation under hypoxia.

P4HA1 Antigen-Profil

Protein Überblick

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit P4HA1

  • prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ000975) Antikörper
  • prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ017131) Antikörper
  • prolyl 4-hydroxylase subunit alpha-1 (Tsp_03346) Antikörper
  • prolyl 4-hydroxylase subunit alpha-1 (Tsp_03347) Antikörper
  • prolyl 4-hydroxylase subunit alpha-1 (Tsp_15957) Antikörper
  • prolyl 4-hydroxylase subunit alpha 1 (P4HA1) Antikörper
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide (P4ha1) Antikörper
  • prolyl 4-hydroxylase subunit alpha 1 (P4ha1) Antikörper
  • AL022634 Antikörper
  • P4ha Antikörper
  • PHalphaI Antikörper

Bezeichner auf Proteinebene für P4HA1

prolyl 4-hydroxylase subunit alpha-1 , procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I , prolyl 4-hydroxylase alpha subunit , prolyl 4-hydroxylase, alpha I subunit , 4-PH alpha-1 , procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1 , C-P4Halpha(I) , collagen prolyl 4-hydroxylase alpha(I) , procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide

GENE ID SPEZIES
6031971 Culex quinquefasciatus
6051272 Culex quinquefasciatus
10909085 Trichinella spiralis
10909086 Trichinella spiralis
10909998 Trichinella spiralis
100037299 Sus scrofa
450891 Pan troglodytes
18451 Mus musculus
5033 Homo sapiens
479242 Canis lupus familiaris
64475 Rattus norvegicus
518288 Bos taurus
423704 Gallus gallus
100172658 Pongo abelii
Ausgewählte Anbieter für anti-P4HA1 (P4HA1) Antikörper
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