Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) Proteine (PDCD4)

PDCD4 is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Zusätzlich bieten wir Ihnen PDCD4 Antikörper (250) und PDCD4 Kits (18) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PDCD4 27250 Q53EL6
PDCD4 18569 Q61823
PDCD4 64031 Q9JID1
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top PDCD4 Proteine auf antikoerper-online.de

Showing 10 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert Figure annotation denotes ug of protein loaded and % gel used. 100 μg Anmelden zum Anzeigen 10 bis 13 Tage
356,80 €
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 8 bis 9 Tage
392,86 €
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 13 bis 15 Tage
214,29 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.156,83 €
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.163,81 €
Details
Hefe Pongo abelii His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.163,81 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert   1 mg Anmelden zum Anzeigen 6 bis 8 Tage
5.531,43 €
Details

PDCD4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartnern

Human Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartner

  1. miRNA-96 is significantly overexpressed in glioma tissues. Moreover, miRNA-96 plays a critical role in apoptosis by inhibiting the expression of PDCD4 in glioma.

  2. Supporting the clinical relevance of our results, we found an inverse correlation between ErbB-2 (zeige ERBB2 Proteine)/Stat3 (zeige STAT3 Proteine) nuclear co-expression and PDCD4 expression in ErbB-2 (zeige ERBB2 Proteine)-positive primary invasive breast cancer

  3. this study highlights an oncomiR role for miR (zeige MLXIP Proteine)-181b in regulating PDCD4 in colorectal cancer and suggests that miR (zeige MLXIP Proteine)-181b may be a novel molecular therapeutic target for colorectal cancer.

  4. Higher PDCD4 expression plays a role in polycystic ovary syndrome by affecting obesity, insulin (zeige INS Proteine) resistance, lipid metabolism disorders, and granulosa cell apoptosis.

  5. results revealed that microRNA 200a inhibits erythroid differentiation by targeting PDCD4 and THRB (zeige THRB Proteine)

  6. The expression of miR (zeige MLXIP Proteine)-21 and PDCD4 at messenger RNA level was evaluated by quantitative real-time polymerase chain reaction, while the protein level of PDCD4 was determined by Western blotting. Authors found that locked nucleic acid-anti-miR (zeige MLXIP Proteine)-21 transfection was associated with a significant reduction in metastatic properties as assessed by the in ovo model.

  7. Data indicate that programmed cell death 4 (PDCD4) was identified to be a target of ubiquitin-specific protease 4 (USP4 (zeige USP4 Proteine)), which plays a role as a tumor suppressor.

  8. PDCD4 down-regulation is involved in the progression of several types of solid tumor.

  9. Results show that exosome-shuttling miR-21 represses PDCD4 protein expression by binding to 3'-UTR in esophageal cancer cells.

  10. miR (zeige MLXIP Proteine)-21, acting on PDCD4, which interacts with Twist1 (zeige TWIST1 Proteine) and represses the expression of Twist1 (zeige TWIST1 Proteine), contributes to the EMT (zeige ITK Proteine) induced by arsenite in transformed bronchial epithelial cells.

Mouse (Murine) Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartner

  1. -induced expression of PDCD4 is associated with increased beta cell death.

  2. miR (zeige MLXIP Proteine)-155 not only directly inhibited SOCS1 (zeige SOCS1 Proteine) expression, but also increased the expression of p-STAT (zeige STAT1 Proteine) and PDCD4, as well as the production of proinflammation mediators IL-6 (zeige IL6 Proteine) and TNF-alpha (zeige TNF Proteine) in atherogenesis

  3. our data suggest that Pdcd4 as a crucial regulator in SGs (zeige SKI Proteine) induced by ox-LDL or HFD maybe a potential target for mitigating SG-associated stress responses in obesity and related diseases.

  4. Pdcd4 deficiency attenuates atherosclerosis in hyperlipidemic mice in part through the upregulation of the anti-inflammatory cytokine IL-10 (zeige IL10 Proteine).

  5. PDCD4 Deficiency Aggravated Colitis and Colitis-associated Colorectal Cancer Via Promoting IL-6 (zeige IL6 Proteine)/STAT3 (zeige STAT3 Proteine) Pathway.

  6. Study found that miR-16 (zeige GDE1 Proteine) was the direct regulatory element of PDCD4 and played a vital role in atherosclerosis by regulating PDCD4 and the downstream NF-kappaB (zeige NFKB1 Proteine) and MAPK (zeige MAPK1 Proteine) pathways.

  7. Pdcd4 produces unfavorable influences on adipose-derived stem cells(ADSC) stemness, which contribute to adipose dysfunction, obesity and metabolic syndromes, thereby proposing Pdcd4 as a potential intervening target for regulating ADSC cells function.

  8. PDCD4 serves as an important regulator of keratinocytes proliferation and contact inhibition in vitro.

  9. In conclusion, miR (zeige MLXIP Proteine)-21 is sensitive to high-concentration glucose treatment in macrophages, and appears to have a protective effect in macrophage apoptosis induced by high concentrations of glucose via PDCD4.

  10. atheroprotective unidirectional pulsatile shear stress affects the expression of PDCD4 in endothelial cells

Zebrafish Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartner

  1. miR (zeige MYLIP Proteine)-21 plays a necessary role in cardiac valvulogenesis, in large part due to an obligatory downregulation of PDCD4

Pig (Porcine) Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartner

  1. TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4/NF-kappaB (zeige NFKB1 Proteine)/ TNF-alpha (zeige TNF Proteine) pathway in cardiomyocytes.

PDCD4 Protein Überblick

Protein Überblick

This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit PDCD4

  • programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4)
  • programmed cell death 4 (Pdcd4)
  • programmed cell death 4b (pdcd4b)
  • programmed cell death 4 (neoplastic transformation inhibitor) (pdcd4)
  • programmed cell death 4 (pdcd4)
  • cb45 Protein
  • D19Ucla1 Protein
  • Dug Protein
  • h731 Protein
  • Ma3 Protein
  • MGC69337 Protein
  • MGC79760 Protein
  • PDCD4 Protein
  • sb:cb45 Protein
  • Tis Protein
  • wu:fc84b08 Protein

Bezeichner auf Proteinebene für PDCD4

neoplastic transformation inhibitor protein , nuclear antigen H731 , programmed cell death protein 4 , protein 197/15a , protein MA-3 , topoisomerase-inhibitor suppressed protein , death up-regulated gene protein , death-upregulated , programmed cell death 4 , protein I11/6 , programmed cell death 4 (neoplastic transformation inhibitor) , programmed cell death protein 4-like

GENE ID SPEZIES
27250 Homo sapiens
18569 Mus musculus
64031 Rattus norvegicus
321061 Danio rerio
380222 Xenopus laevis
448531 Xenopus (Silurana) tropicalis
506724 Bos taurus
374191 Gallus gallus
407925 Xenopus (Silurana) tropicalis
450735 Pan troglodytes
477818 Canis lupus familiaris
695345 Macaca mulatta
100021762 Monodelphis domestica
100080517 Ornithorhynchus anatinus
100354557 Oryctolagus cuniculus
100413000 Callithrix jacchus
100469480 Ailuropoda melanoleuca
100584426 Nomascus leucogenys
100157112 Sus scrofa
100173014 Pongo abelii
Ausgewählte Anbieter für PDCD4 Proteine (PDCD4)
Haben Sie etwas anderes gesucht?