anti-Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Antikörper

PDCD4 is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Zusätzlich bieten wir Ihnen PDCD4 Kits (19) und PDCD4 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDCD4 27250 Q53EL6
PDCD4 18569 Q61823
PDCD4 64031 Q9JID1
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Top anti-PDCD4 Antikörper auf antikoerper-online.de

Showing 10 out of 251 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from 293 cells treated with serum 20% 15', using PDCD4 (Phospho-Ser457) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using PDCD4 (Phospho-Ser457) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HuvEc cells, K562 cells and COS-7 cells, using PDCD4 (Phospho-Ser67) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from 293 cells, using PDCD4 (Ab-457) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using PDCD4 (Ab-457) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IP, IHC, ELISA, WB Affinity purified anti-Pdcd4 was used at a 1:100 dilution to detect Pdcd4 by immunohistochemistry on mouse colon tissue. Tissue was fixed in 4% paraformaldehyde and paraffin embedded. Tissue sections were deparaffinized and treated by trypsinization before staining. 25 μL Anmelden zum Anzeigen 1 bis 2 Tage
$135.00
Details
Human Maus Biotin IHC, ELISA, WB Western Blot of Mouse anti-Pdcd4 phospho S457 Biotin Conjugated antibody. Lane 1: Pdcd4 recombinant protein. Lane 2: none. Load: 100 ng per lane. Primary antibody: Pdcd4 phospho S457 Biotin Conjugated antibody at 1:1,000 for overnight at 4°C. Secondary antibody: HRP Streptavidin secondary antibody at 1:40,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 50 kDa, 50 kDa for Pdcd4 phospho S457. Other band(s): Pdcd4 phospho S457 splice variants and isoforms 50 μg Anmelden zum Anzeigen 1 bis 2 Tage
$295.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB PDCD4 Antibody (Center) (ABIN657922) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the PDCD4 antibody detected the PDCD4 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Huhn Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of PDCD4 (pS457) staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of PDCD4 (pS457) expression in HeLa (A), Jurkat (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$575.00
Details
Human Maus Unkonjugiert EIA, IHC (p), WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Western Blot: PDCD4 Antibody [NBP1-76738] - A-20 cell lysate with PDCD4 antibody at (A) 0.5 and (B) 1ug/ml. Immunohistochemistry-Paraffin: PDCD4 Antibody [NBP1-76738] - Mouse brain tissue with PDCD4 antibody at 2.5 ug/ml. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details

PDCD4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-PDCD4 Antikörper

  1. Human Polyclonal PDCD4 Primary Antibody für IHC, IHC (p) - ABIN4344378 : Baffa, Fassan, Volinia, OHara, Liu, Palazzo, Gardiman, Rugge, Gomella, Croce, Rosenberg: MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets. in The Journal of pathology 2009 (PubMed)
    Show all 7 Pubmed References

  2. Human Polyclonal PDCD4 Primary Antibody für IHC, ELISA - ABIN1002982 : Yang, Jansen, Komar, Zheng, Merrick, Costes, Lockett, Sonenberg, Colburn: The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. in Molecular and cellular biology 2002 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal PDCD4 Primary Antibody für IP, IHC - ABIN129709 : Santhanam, Baker, Hegamyer, Kirschmann, Colburn: Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion. in Oncogene 2010 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal PDCD4 Primary Antibody für IF (p), IHC (p) - ABIN731993 : Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity. in International journal of nanomedicine 2014 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal PDCD4 Primary Antibody für IHC, ELISA - ABIN1043728 : Jansen, Camalier, Colburn: Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. in Cancer research 2005 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal PDCD4 Primary Antibody für IHC, ELISA - ABIN1043755 : Huang, Wu, Loeb, Hsu, Heidersbach, Brincat, Horiuchi, Lebbink, Mo, Goga, McManus: Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 Pubmed References

  7. Cow (Bovine) Polyclonal PDCD4 Primary Antibody für WB - ABIN2792230 : Yang, Cho, Zakowicz, Hegamyer, Sonenberg, Colburn: A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A. in Molecular and cellular biology 2004 (PubMed)
    Show all 3 Pubmed References

  8. Human Polyclonal PDCD4 Primary Antibody für ELISA, WB - ABIN129708 : Eto, Goto, Nakashima, Ura, Abe: Loss of programmed cell death 4 induces apoptosis by promoting the translation of procaspase-3 mRNA. in Cell death and differentiation 2011 (PubMed)

Weitere Antikörper gegen PDCD4 Interaktionspartner

Human Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartner

  1. miRNA-96 is significantly overexpressed in glioma tissues. Moreover, miRNA-96 plays a critical role in apoptosis by inhibiting the expression of PDCD4 in glioma.

  2. Supporting the clinical relevance of our results, we found an inverse correlation between ErbB-2 (zeige ERBB2 Antikörper)/Stat3 (zeige STAT3 Antikörper) nuclear co-expression and PDCD4 expression in ErbB-2 (zeige ERBB2 Antikörper)-positive primary invasive breast cancer

  3. this study highlights an oncomiR role for miR (zeige MLXIP Antikörper)-181b in regulating PDCD4 in colorectal cancer and suggests that miR (zeige MLXIP Antikörper)-181b may be a novel molecular therapeutic target for colorectal cancer.

  4. Higher PDCD4 expression plays a role in polycystic ovary syndrome by affecting obesity, insulin (zeige INS Antikörper) resistance, lipid metabolism disorders, and granulosa cell apoptosis.

  5. results revealed that microRNA 200a inhibits erythroid differentiation by targeting PDCD4 and THRB (zeige THRB Antikörper)

  6. The expression of miR (zeige MLXIP Antikörper)-21 and PDCD4 at messenger RNA level was evaluated by quantitative real-time polymerase chain reaction, while the protein level of PDCD4 was determined by Western blotting. Authors found that locked nucleic acid-anti-miR (zeige MLXIP Antikörper)-21 transfection was associated with a significant reduction in metastatic properties as assessed by the in ovo model.

  7. Data indicate that programmed cell death 4 (PDCD4) was identified to be a target of ubiquitin-specific protease 4 (USP4 (zeige USP4 Antikörper)), which plays a role as a tumor suppressor.

  8. PDCD4 down-regulation is involved in the progression of several types of solid tumor.

  9. Results show that exosome-shuttling miR (zeige MLXIP Antikörper)-21 represses PDCD4 protein expression by binding to 3'-UTR (zeige UTS2R Antikörper) in esophageal cancer cells.

  10. miR (zeige MLXIP Antikörper)-21, acting on PDCD4, which interacts with Twist1 (zeige TWIST1 Antikörper) and represses the expression of Twist1 (zeige TWIST1 Antikörper), contributes to the EMT (zeige ITK Antikörper) induced by arsenite in transformed bronchial epithelial cells.

Mouse (Murine) Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartner

  1. -induced expression of PDCD4 is associated with increased beta cell death.

  2. miR (zeige MLXIP Antikörper)-155 not only directly inhibited SOCS1 (zeige SOCS1 Antikörper) expression, but also increased the expression of p-STAT (zeige STAT1 Antikörper) and PDCD4, as well as the production of proinflammation mediators IL-6 (zeige IL6 Antikörper) and TNF-alpha (zeige TNF Antikörper) in atherogenesis

  3. our data suggest that Pdcd4 as a crucial regulator in SGs (zeige SKI Antikörper) induced by ox-LDL or HFD maybe a potential target for mitigating SG-associated stress responses in obesity and related diseases.

  4. Pdcd4 deficiency attenuates atherosclerosis in hyperlipidemic mice in part through the upregulation of the anti-inflammatory cytokine IL-10 (zeige IL10 Antikörper).

  5. PDCD4 Deficiency Aggravated Colitis and Colitis-associated Colorectal Cancer Via Promoting IL-6 (zeige IL6 Antikörper)/STAT3 (zeige STAT3 Antikörper) Pathway.

  6. Study found that miR-16 (zeige GDE1 Antikörper) was the direct regulatory element of PDCD4 and played a vital role in atherosclerosis by regulating PDCD4 and the downstream NF-kappaB (zeige NFKB1 Antikörper) and MAPK (zeige MAPK1 Antikörper) pathways.

  7. Pdcd4 produces unfavorable influences on adipose-derived stem cells(ADSC) stemness, which contribute to adipose dysfunction, obesity and metabolic syndromes, thereby proposing Pdcd4 as a potential intervening target for regulating ADSC cells function.

  8. PDCD4 serves as an important regulator of keratinocytes proliferation and contact inhibition in vitro.

  9. In conclusion, miR (zeige MLXIP Antikörper)-21 is sensitive to high-concentration glucose treatment in macrophages, and appears to have a protective effect in macrophage apoptosis induced by high concentrations of glucose via PDCD4.

  10. atheroprotective unidirectional pulsatile shear stress affects the expression of PDCD4 in endothelial cells

Zebrafish Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartner

  1. miR (zeige MYLIP Antikörper)-21 plays a necessary role in cardiac valvulogenesis, in large part due to an obligatory downregulation of PDCD4

Pig (Porcine) Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) Interaktionspartner

  1. TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4/NF-kappaB (zeige NFKB1 Antikörper)/ TNF-alpha (zeige TNF Antikörper) pathway in cardiomyocytes.

PDCD4 Antigen-Profil

Protein Überblick

This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit PDCD4

  • programmed cell death 4 (PDCD4) Antikörper
  • programmed cell death 4 (Pdcd4) Antikörper
  • programmed cell death 4b (pdcd4b) Antikörper
  • programmed cell death 4 L homeolog (pdcd4.L) Antikörper
  • programmed cell death 4 like (LOC448531) Antikörper
  • programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4) Antikörper
  • programmed cell death 4 (pdcd4) Antikörper
  • cb45 Antikörper
  • D19Ucla1 Antikörper
  • Dug Antikörper
  • h731 Antikörper
  • Ma3 Antikörper
  • MGC69337 Antikörper
  • MGC79760 Antikörper
  • PDCD4 Antikörper
  • sb:cb45 Antikörper
  • Tis Antikörper
  • wu:fc84b08 Antikörper

Bezeichner auf Proteinebene für PDCD4

neoplastic transformation inhibitor protein , nuclear antigen H731 , programmed cell death protein 4 , protein 197/15a , protein MA-3 , topoisomerase-inhibitor suppressed protein , death up-regulated gene protein , death-upregulated , programmed cell death 4 , protein I11/6 , programmed cell death 4 (neoplastic transformation inhibitor) , programmed cell death protein 4-like

GENE ID SPEZIES
27250 Homo sapiens
18569 Mus musculus
64031 Rattus norvegicus
321061 Danio rerio
380222 Xenopus laevis
448531 Xenopus (Silurana) tropicalis
506724 Bos taurus
374191 Gallus gallus
407925 Xenopus (Silurana) tropicalis
450735 Pan troglodytes
477818 Canis lupus familiaris
695345 Macaca mulatta
100021762 Monodelphis domestica
100080517 Ornithorhynchus anatinus
100354557 Oryctolagus cuniculus
100413000 Callithrix jacchus
100469480 Ailuropoda melanoleuca
100584426 Nomascus leucogenys
100157112 Sus scrofa
100173014 Pongo abelii
Ausgewählte Anbieter für anti-PDCD4 (PDCD4) Antikörper
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