anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) Antikörper

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Zusätzlich bieten wir Ihnen KCNA3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KCNA3 3738 P22001
KCNA3 16491 P16390
KCNA3 29731 P15384
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Top anti-KCNA3 Antikörper auf antikoerper-online.de

Showing 10 out of 120 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells treated with starved 24h, using Kv1.3/KCNA3 (Phospho-Tyr135) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using Kv1.3/KCNA3 (Phospho-Tyr135) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of KCNA3 Antibody (Center) in A549 cell line lysates (35ug/lane).This demonstrates the KCNA3 antibody detected the KCNA3 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Huhn Kaninchen Unkonjugiert IP, WB Western blot analysis of Kv1.3 expression in A549 (A) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Huhn Kaninchen Unkonjugiert WB Western blot analysis of Kv1.3 (pY187) expression in HEK293T EGF-treated (A), SP2/0 EGF-treated (B), PC12 EGF-treated (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$575.00
Details
Human Kaninchen Unkonjugiert WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Kv1.3/KCNA3 (Ab-135) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HuvEc cells, using Kv1.3/KCNA3 (Ab-135) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert WB KCNA3 monoclonal antibody (M01), clone 1D8 Western Blot analysis of KCNA3 expression in HeLa NE. Detection limit for recombinant GST tagged KCNA3 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert WB KCNA3 Antibody (Center) (ABIN658606) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the KCNA3 antibody detected the KCNA3 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

KCNA3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-KCNA3 Antikörper

  1. Mammalian Monoclonal KCNA3 Primary Antibody für ISt, IHC - ABIN1304749 : Cidad, Novensà, Garabito, Batlle, Dantas, Heras, López-López, Pérez-García, Roqué: K+ channels expression in hypertension after arterial injury, and effect of selective Kv1.3 blockade with PAP-1 on intimal hyperplasia formation. in Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2014 (PubMed)
    Show all 21 Pubmed References

Weitere Antikörper gegen KCNA3 Interaktionspartner

Human Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) Interaktionspartner

  1. the tertiary structure of the C-terminal domain of Kv1.3 is necessary and sufficient for Kv1.3- KCNE4 (zeige KCNE4 Antikörper) interaction.

  2. results identify a caveolin-binding domain in Kv1 (zeige KCNA5 Antikörper) channels and highlight the mechanisms that govern the regulation of channel surface localization during cellular processes

  3. we report that Kv1.3-NPs (zeige NPS Antikörper) reduced NFAT (zeige NFATC1 Antikörper) activation and CD40L (zeige CD40LG Antikörper) expression exclusively in CD45RO(+) T cells. Furthermore, Kv1.3-NPs (zeige NPS Antikörper) suppressed cytokine release and induced a phenotype switch of T cells from predominantly memory to naive.

  4. The implication of Kv1.3 in a wide repertoire of human pathologies indicates this channel is an important therapeutic target.

  5. Results contribute to the characterization of leukemic B cells, as it shows that upregulation of Kv1.3 in pathologic B lymphocytes is linked to the oncogenic B-RAF (zeige SNRPE Antikörper) signaling.

  6. Data suggest that C-terminus is necessary for Kv1.3-induced cell proliferation; the mechanism involves accessibility of key docking sites at the C terminus; phosphorylation of Tyr (zeige TYR Antikörper)-447 by MAP kinase (zeige MAPK1 Antikörper) signal cascade appears crucial.

  7. concluded that Kv1.3 may stimulate macrophage migration through the activation of ERK (zeige EPHB2 Antikörper).

  8. The inhibition of Kv1.3 channels might be involved in antiproliferative and proapoptotic effects of the compounds observed in cancer cell lines expressing these channels.

  9. Kv1.3 channels modulate human vascular smooth muscle cells proliferation independently of mTOR (zeige FRAP1 Antikörper) signaling pathway.

  10. actin dynamics regulates the membrane motility of Kv1.3 channels.

Mouse (Murine) Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3) Interaktionspartner

  1. These studies reveal unexpected roles of Kv1.3 subunit-containing channels in the regulation of firing patterns of striatal cholinergic interneurons, which were thought to be largely dependent on KCa (zeige CSN3 Antikörper) channels.

  2. the tertiary structure of the C-terminal domain of Kv1.3 is necessary and sufficient for Kv1.3- KCNE4 (zeige KCNE4 Antikörper) interaction.

  3. promotes B lymphocyte (zeige AKAP17A Antikörper) activation, proliferation and monocyte chemotaxis

  4. Changes in Kv1.3 subcellular distribution upon EGFR (zeige EGFR Antikörper) activation were due to Kv1.3 clathrin-dependent endocytosis, which targets the Kv1.3 channels to the lysosomal degradative pathway.

  5. Kv1.3 channel serves as a negative regulator of phagocytosis in macrophages and can be a potential target in the treatment of macrophage dysfunction

  6. concluded that Kv1.3 may stimulate macrophage migration through the activation of ERK (zeige EPHB2 Antikörper).

  7. A compensatory upregulation of the potassium channels K2P3.1 (zeige KCNK3 Antikörper) and KV1.3 seems to counterbalance the deletion of K2P5.1 (zeige KCNK5 Antikörper).

  8. JAK2 (zeige JAK2 Antikörper) participates in the signalling, regulating the voltage-gated K(+) channel (zeige KCND3 Antikörper) KCNA3.

  9. Antigenic Stimulation of Kv1.3-Deficient Th Cells Gives Rise to a Population of Foxp3 (zeige FOXP3 Antikörper)-Independent T Cells with Suppressive Properties

  10. A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmation

KCNA3 Antigen-Profil

Protein Überblick

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.

Genbezeichner und Symbole assoziert mit KCNA3

  • potassium voltage-gated channel subfamily A member 3 (KCNA3) Antikörper
  • potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog (kcna3.S) Antikörper
  • potassium voltage-gated channel, shaker-related subfamily, member 3 (Kcna3) Antikörper
  • potassium voltage-gated channel subfamily A member 3 (Kcna3) Antikörper
  • cKv1.1 Antikörper
  • HGK5 Antikörper
  • HLK3 Antikörper
  • HPCN3 Antikörper
  • HUKIII Antikörper
  • Kca1-3 Antikörper
  • kcna3b-a Antikörper
  • Kv1.3 Antikörper
  • Kv1.3-glyb Antikörper
  • Kv1.3B Antikörper
  • Mk-3 Antikörper
  • MK3 Antikörper
  • PCN3 Antikörper

Bezeichner auf Proteinebene für KCNA3

glibenclamide-sensitive voltage-gated potassium channel , potassium voltage-gated channel subfamily A member 3 , potassium voltage-gated channel, shaker-related subfamily, member 3 , shaker-like potassium channel subunit Kv1.3B , potassium channel 3 , type n potassium channel , voltage-gated K(+) channel HuKIII , voltage-gated potassium channel protein Kv1.3 , voltage-gated potassium channel subunit Kv1.3 , MK3 , Voltage-gated potassium channel protein Kv1.3 (RGK5) (RCK3) (KV3) , potassium voltage gated channel, shaker related subfamily, member 3 , KV3 , RCK3 , RGK5 , voltage-gated potassium channel subunit Kv3 , Shaker-like voltage-gated potassium channel cKv1.1 , shaker subfamily potassium channel Kv1.3 alpha subunit , voltage-gated Kv1.3 potassium channel

GENE ID SPEZIES
100328945 Oryctolagus cuniculus
373847 Xenopus laevis
3738 Homo sapiens
16491 Mus musculus
29731 Rattus norvegicus
404303 Gallus gallus
525507 Bos taurus
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