anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) Antikörper

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Zusätzlich bieten wir Ihnen Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 Kits (5) und Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KCNJ3 3760 P48549
KCNJ3 16519 P63250
KCNJ3 50599 P63251
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Top anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 Antikörper auf antikoerper-online.de

Showing 10 out of 105 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Kcnj3 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Maus Kaninchen Unkonjugiert WB Western blot analysis of rat brain membranes: 1. Anti-Kir3.1 (GIRK1) antibody, (1:200). 2. Anti-Kir3.1 (GIRK1) antibody, preincubated with the control antigen. 25 μL Anmelden zum Anzeigen 10 bis 11 Tage
$535.71
Details
Hund Kaninchen Unkonjugiert IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Mouse kidney lysate probed with Rabbit Anti-GIRK1 Polyclonal Antibody  at 1:5000 90min in 37˚C 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$307.45
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using GIRK1/KIR3.1/KCNJ3 (Ab-185) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using GIRK1/KIR3.1/KCNJ3 (Ab-185) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from RAW264.7 cells treated with Insulin 0.01U/ml 15', using GIRK1/KIR3.1/KCNJ3 (Phospho-Ser185) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using GIRK1/KIR3.1/KCNJ3 (Phospho-Ser185) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, WB 100 μL Anmelden zum Anzeigen 16 Days
$175.80
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Huhn Kaninchen Unkonjugiert IC, IF, WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
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Huhn Kaninchen Unkonjugiert IC, IF, IHC, WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$575.00
Details
Human Maus Unkonjugiert IF, WB Anti-KCNJ3 mouse monoclonal antibody (ABIN2455445) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY KCNJ3 (RC205322). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY KCNJ3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-KCNJ3. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$423.50
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB Western Blot: Kir3.1 Antibody [NBP1-32958] - Analysis of Kir3.1 on A431 lysates (Lane A), H1299 lysates (Lane B) and Hela (Lane C) at a dilution of 1:1000. 30 ug of whole cell lysate loaded on 7.5% SDS PAGE gel. Immunohistochemistry-Paraffin: Kir3.1 Antibody [NBP1-32958] - Paraffin-embedded DU145 xenograft, using antibody at 1:100 dilution. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
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KCNJ3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 Antikörper

  1. Dog (Canine) Polyclonal KCNJ3 Primary Antibody für IF (p), IHC (p) - ABIN719741 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014 (PubMed)

Weitere Antikörper gegen Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 Interaktionspartner

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) Interaktionspartner

  1. Results clearly corroborate that overexpression of GIRK1 protein exerts profound effects on wound healing, chemoinvasion and cellular motility in the MCF-7 breast cancer cell line suggesting a role to promote invasion and metastasis.

  2. GIRK1/GIRK4 (zeige KCNJ5 Antikörper) hetero-tetramers are not activated by Na+, but rather are in a permanent state of high responsiveness to G proteins beta-gamma, suggesting that the GIRK1 subunit functions like a GIRK4 (zeige KCNJ5 Antikörper) subunit with Na+ permanently bound.

  3. The findings of this study suggest that variations in KCNJ3 genes are associated with both mild and severe persistent breast pain after breast cancer surgery.

  4. For KCNJ3 rs7574878, individuals who were heterozygous or homozygous for the rare G allele (TT versus TG+ GG) had a 48% reduction in the odds of reporting preoperative breast pain.

  5. we show that Kir3.1, in the absence of trafficking partner subunits, can exit the endoplasmic reticulum (ER) and reach the Golgi (though not the plasma membrane)

  6. Conformational changes at the Gbetagamma/Kir3 interface were lost when Kir3.1 subunits were replaced.

  7. These data suggest that the KCNJ3 gene is genetically associated with schizophrenia in Asian populations and add further evidence to the "channelopathy theory of psychiatric illnesses".

  8. Kir3.1 channel is involved in the TLR4 (zeige TLR4 Antikörper)-mediated signal at an early event by facilitating the recruitment of TLR4 (zeige TLR4 Antikörper) into lipid raft.

  9. halothane (zeige RYR1 Antikörper) predominantly interferes with Gbetagamma-mediated Kir3 currents, such as those functioning during inhibitory synaptic activity

  10. The very high abundance of mRNA's encoding GIRK1 together with the presence of GIRK1 protein suggests a pathophysiological role in breast cancer

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) Interaktionspartner

  1. Kir (zeige GEM Antikörper) 3.1 channels are important for supraspinal antinociception and presynaptic GABA release inhibition by oxycodone in the femur bone cancer model

  2. GABA neurons in the ventral tegmental area express GIRK1 (and GIRK2 (zeige KCNJ6 Antikörper)) subunits.

  3. siRNA knock-down of NgR1 (zeige NEUROG1 Antikörper) resulted in a selective increase of GABAB R1 and GABAB R2 protein and an increase in GIRK1.

  4. Discontinuous and sometime opposing elements in Girk1 underlie the Girk1-dependent potentiation of receptor-dependent and receptor-independent heteromeric channel activity.

  5. Mechanism for functional dysregulation in the dorsal raphe follows tyrosine phosphorylation of repeated stress-activated Kir3.1 channels.

  6. NMR analyses of the Gbetagamma binding and conformational rearrangements of the cytoplasmic pore of G protein-activated inwardly rectifying potassium channel 1 (zeige KCNA5 Antikörper) (GIRK1).

  7. Agonist-induced localization of Gq-coupled receptors and G protein-gated inwardly rectifying K+ (GIRK) channels to caveolae determines receptor specificity of phosphatidylinositol 4,5-bisphosphate signaling

  8. The atrial potassium channel (zeige KCNAB2 Antikörper), I(KACH), ion channel gating is accelerated in atrial myocytes through the RGS6 (zeige RGS6 Antikörper)/Gbeta5 (zeige GNB5 Antikörper) complex.

  9. Dopamine neurons from Girk1 knock-out mice (and Girk2 (zeige KCNJ6 Antikörper)) exhibited elevated glutamatergic neurotransmission and increased synaptic levels of AMPA (zeige GRIA3 Antikörper) glutamate (zeige GRIN1 Antikörper) receptors.

  10. Data suggest HL-1 (zeige ASGR1 Antikörper) cells express GIRK1/4 and M2 muscarinic receptors and are a good model to study acetylcholine-activated potassium currents.

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3) Antigen-Profil

Protein Überblick

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Genbezeichner und Symbole assoziert mit KCNJ3

  • potassium voltage-gated channel subfamily J member 3 (KCNJ3) Antikörper
  • potassium inwardly-rectifying channel, subfamily J, member 3 (Kcnj3) Antikörper
  • potassium voltage-gated channel subfamily J member 3 (Kcnj3) Antikörper
  • girk1 Antikörper
  • Kcnf3 Antikörper
  • KGA Antikörper
  • Kir3.1 Antikörper

Bezeichner auf Proteinebene für KCNJ3

G protein-activated inward rectifier potassium channel 1 , GIRK-1 , inward rectifier K(+) channel Kir3.1 , inward rectifier K+ channel KIR3.1 , potassium channel, inwardly rectifying subfamily J member 3 , potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e , potassium inwardly-rectifying channel J3 , GIRK1 , KGA , KGB1 , potassium channel inwarding rectifying channel subfamily J member 3 , potassium channel subunit Kir3.1 type 3 delta , inward rectifying potassium channel, Kir3.1

GENE ID SPEZIES
3760 Homo sapiens
16519 Mus musculus
50599 Rattus norvegicus
100190980 Cavia porcellus
396369 Gallus gallus
488355 Canis lupus familiaris
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