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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 15 Proteine (KCNJ15)

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Zusätzlich bieten wir Ihnen KCNJ15 Antikörper (38) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
KCNJ15 3772 Q99712
KCNJ15 16516 O88932
Ratte KCNJ15 KCNJ15 170847 Q91ZF1
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Showing 3 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 46 bis 51 Tage
4.032,65 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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KCNJ15 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,
Mouse (Murine)
,

Weitere Proteine zu Potassium Inwardly-Rectifying Channel, Subfamily J, Member 15 (KCNJ15) Interaktionspartnern

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 15 (KCNJ15) Interaktionspartner

  1. KCNJ15 couples with polyamines in sensing weak electric fields.

  2. RNA-seq evidence of biallelic expression of KCNJ15 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of KCNJ15 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (zeige WRB Proteine) differentially methylated region (DMR (zeige WDR20 Proteine)) in disomic controls or trisomy (Down syndrome) individuals.

  3. KCNJ15 has a major role in histamine-stimulated gastric acid secretion.

  4. We had performed a replication study using an independent larger Japanese population for the association of rs3746876 within KCNJ15, and observed a significant association of rs3746876 with type 2 diabetes, but this study failed to find original finding.

  5. It was shown that downregulation of Kcnj15 leads to increased insulin (zeige INS Proteine) secretion in vitro and in vivo. The mechanism for regulating insulin (zeige INS Proteine) secretion inolved a calcium-sensiong receptor.

  6. KCNJ15 is a previously unreported susceptibility gene for T2DM among Asians

  7. The potential synergy and consequences of the overexpression of KIR4.2 and KIR3.2 (zeige KCNJ6 Proteine) in Down's syndrome brain development are discussed.

  8. Calcium-sensing receptor (zeige CASR Proteine) interacts directly with Kir4.1 (zeige KCNJ10 Proteine) and Kir4.2 and can decrease their currents.

  9. MUPP1 and Kir4.2 may participate in a protein complex in the nephron that could regulate transport of K(+) as well as other ions.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 15 (KCNJ15) Interaktionspartner

  1. Data show that KCNJ15 inward rectifier potassium channel and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents are changed in Trisomic neuron.

  2. It was shown that downregulation of Kcnj15 leads to increased insulin (zeige INS Proteine) secretion in vitro and in vivo. The mechanism for regulating insulin (zeige INS Proteine) secretion inolved a calcium-sensiong receptor.

  3. in nonsecreting parietal cells, KCNJ15 is stored in vesicles distinct from the H(+)-K(+)-ATPase (zeige ATP4b Proteine)-enriched tubulovesicles. Furthermore, upon stimulation, KCNJ15 and H(+)-K(+)-ATPase (zeige ATP4b Proteine) both translocate to the apical membrane for active acid secretion.

KCNJ15 Protein Überblick

Protein Überblick

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit KCNJ15

  • potassium inwardly-rectifying channel, subfamily J, member 15 (KCNJ15)
  • potassium inwardly-rectifying channel, subfamily J, member 15 (Kcnj15)
  • 4930414N08Rik Protein
  • AI182284 Protein
  • AI267127 Protein
  • IRKK Protein
  • KCNJ15 Protein
  • Kir1.3 Protein
  • Kir4.2 Protein

Bezeichner auf Proteinebene für KCNJ15

potassium inwardly-rectifying channel, subfamily J, member 15 , ATP-sensitive inward rectifier potassium channel 15 , potassium inwardly-rectifying channel J15 , Potassium channel, inwardly rectifying subfamily J member 15 , inward rectifier K(+) channel Kir1.3 , inward rectifier K(+) channel Kir4.2 , inward rectifier K+ channel KIR4.2 , potassium channel, inwardly rectifying subfamily J member 15 , inward rectifier K+ channel Kir4.2 , inwardly rectifying potassium channel Kir1.3

GENE ID SPEZIES
427984 Gallus gallus
487759 Canis lupus familiaris
522184 Bos taurus
693427 Macaca mulatta
747512 Pan troglodytes
100602180 Nomascus leucogenys
3772 Homo sapiens
16516 Mus musculus
170847 Rattus norvegicus
100713999 Cavia porcellus
100135565 Cavia porcellus
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