anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Antikörper

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Zusätzlich bieten wir Ihnen Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KCNJ1 3758 P48048
KCNJ1 24521 P35560
KCNJ1 56379 O88335
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Top anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Antikörper auf antikoerper-online.de

Showing 10 out of 88 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-KCNJ1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of A549 cells, using ROMK/Kir1.1 (Ab-44/25) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using ROMK/Kir1.1 (Phospho-Ser44/25) Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using ROMK/Kir1.1 (Phospho-Ser44/25) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: KCNJ1 Antibody [NBP1-36965] - (1ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: KCNJ1 Antibody [NBP1-82874] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunohistochemistry-Paraffin: KCNJ1 Antibody [NBP1-82874] - Staining of human kidney shows distinct membranous positivity in distal renal tubules. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$439.69
Details
Human Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Kaninchen Unkonjugiert WB KCNJ1 Antibody (C-term)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KCNJ1 antibody detected the KCNJ1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details

KCNJ1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Antikörper

  1. Human Polyclonal KCNJ1 Primary Antibody für IHC, IHC (p) - ABIN4328476 : Vidal-Petiot, Elvira-Matelot, Mutig, Soukaseum, Baudrie, Wu, Cheval, Huc, Cambillau, Bachmann, Doucet, Jeunemaitre, Hadchouel: WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)

  2. Human Polyclonal KCNJ1 Primary Antibody für ELISA, WB - ABIN451810 : Ji, Foo, ORoak, Zhao, Larson, Simon, Newton-Cheh, State, Levy, Lifton: Rare independent mutations in renal salt handling genes contribute to blood pressure variation. in Nature genetics 2008 (PubMed)

  3. Cow (Bovine) Polyclonal KCNJ1 Primary Antibody für WB - ABIN2776290 : Tobin, Tomaszewski, Braund, Hajat, Raleigh, Palmer, Caulfield, Burton, Samani: Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population. in Hypertension 2008 (PubMed)

Weitere Antikörper gegen Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 Interaktionspartner

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Interaktionspartner

  1. Data suggest underlying pathology for some patients with type II Bartter syndrome is linked to stability of ROMK1 in ERAD pathway; using a yeast expression system, cells can be rescued by wild-type (rat) ROMK1 but not by ROMK1 containing any one of four mutations found in (human) type II Bartter syndrome; mutant ROMKs are significantly less stable than wild-type ROMK. (ERAD = endoplasmic reticulum-associated degradation)

  2. WNK4 (zeige WNK4 Antikörper) is a substrate of SFKs and the association of c-Src (zeige SRC Antikörper) and PTP-1D (zeige PTPN11 Antikörper) with WNK4 (zeige WNK4 Antikörper) at Tyr (zeige TYR Antikörper)(1092) and Tyr (zeige TYR Antikörper)(1143) plays an important role in modulating the inhibitory effect of WNK4 (zeige WNK4 Antikörper) on ROMK

  3. knockdown of KCNJ1 in HK-2 (zeige HK2 Antikörper) cells promoted cell proliferation. Collectively, these data highlight that KCNJ1, low-expressed in ccRCC and associated with poor prognosis, plays an important role in ccRCC cell growth and metastasis

  4. The association between polymorphisms in KCNJ1, SLC12A1 (zeige SLC12A1 Antikörper), and 7 other genes and calcium intake and colorectal neoplasia risk was studied.

  5. A KCNJ1 SNP was associated with increased FG during HCTZ treatment.

  6. Molecular analysis revealed a compound heterozygous mutation in the KCNJ1 gene, consisting of a novel K76E and an already described V315G mutation, both affecting functional domains of the channel protein.

  7. Findings suggest that 11q24 is a susceptible locus for openness, with KCNJ1 as the possible candidate gene.

  8. no mutation in the KCNJ1 gene, among patients suffering from bartter and Gitelman syndromes

  9. PI3K (zeige PIK3CA Antikörper)-activating hormones inhibit ROMK by enhancing its endocytosis via a mechanism that involves phosphorylation of WNK1 (zeige WNK1 Antikörper) by Akt1 (zeige AKT1 Antikörper) and SGK1 (zeige SGK1 Antikörper).

  10. THGP (zeige UMOD Antikörper) modulation of ROMK function confers a new role of THGP (zeige UMOD Antikörper) on renal ion transport and may contribute to salt wasting observed in FJHN/MCKD-2 (zeige UMOD Antikörper)/GCKD patients.

Cow (Bovine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Interaktionspartner

  1. The findings support ROMK as the pore-forming subunit of the cytoprotective mitoK(ATP) channel in heart mitochondria.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Interaktionspartner

  1. The results provide evidence that NHERF1 (zeige SLC9A3R2 Antikörper) mediates K(+) current activity through acceleration of the surface expression of ROMK1 K(+) channels in M-1 cells.

  2. ENaC (zeige SCNN1A Antikörper) and ROMK channel activity in kidney tubules are inhibited in TgWnk4(pseudoaldosteronism type II) mice. Wnk4 (zeige WNK4 Antikörper)(PHAII)-induced inhibition of ENaC (zeige SCNN1A Antikörper) and ROMK may contribute to the suppression of K(+) secretion in the tubules.

  3. The differential regulation of ROMK, large-conductance Ca(2 (zeige CA2 Antikörper)+)-activated K(+) (BK) channel (zeige KCNMA1 Antikörper), BK-alpha and NKCC2 (zeige SLC12A1 Antikörper) between female and male mice, at least, were partly mediated via WNK1 (zeige WNK1 Antikörper) pathway, which may contribute to the sexual dimorphism of plasma K(+) and blood pressure control.

  4. Suggest that the hyperkalemia in knock-in mouse with the CUL3 (zeige CUL3 Antikörper)(Delta403-459) mutation is not caused by reduced ROMK expression in the distal nephron.

  5. animal knockouts of ROMK1 do not produce Bartter phenotype. ROMK1 is critical in response to high K intake-stimulated K+ secretion in the collecting tubule.

  6. Lovastatin stimulates ROMK1 channels by inducing PI(4,5)P2 synthesis, suggesting that the drug could reduce cyclosporine-induced nephropathy.

  7. ROMK1 protein abundance and activity are down-regulated by SPAK (zeige STK39 Antikörper) and OSR1 (zeige OSR1 Antikörper)

  8. It was concluded that miR (zeige MLXIP Antikörper)-194 regulates ROMK channel activity by modulating ITSN1 (zeige ITSN1 Antikörper) expression thereby enhancing ITSN1 (zeige ITSN1 Antikörper)/WNK-dependent endocytosis.

  9. THGP (zeige UMOD Antikörper) modulation of ROMK function confers a new role of THGP (zeige UMOD Antikörper) on renal ion transport and may contribute to salt wasting observed in FJHN/MCKD-2 (zeige UMOD Antikörper)/GCKD patients.

  10. hypertension resistance sequence variants inhibit ROMK channel function by different mechanisms

Zebrafish Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Interaktionspartner

  1. Kcnj1 is expressed in cells associated with osmoregulation and acts as a K+ efflux pathway that is important in maintaining extracellular levels of potassium ion in the developing embryo.

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Antigen-Profil

Protein Überblick

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit KCNJ1

  • potassium voltage-gated channel subfamily J member 1 (KCNJ1) Antikörper
  • potassium voltage-gated channel subfamily J member 1 L homeolog (kcnj1.L) Antikörper
  • potassium voltage-gated channel subfamily J member 1 (kcnj1) Antikörper
  • potassium voltage-gated channel subfamily J member 1 (Kcnj1) Antikörper
  • potassium inwardly-rectifying channel, subfamily J, member 1 (Kcnj1) Antikörper
  • potassium channel, inwardly rectifying subfamily J, member 15 L homeolog (kcnj15.L) Antikörper
  • potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 (kcnj1a.1) Antikörper
  • Kcnj Antikörper
  • kcnj1 Antikörper
  • Kir1.1 Antikörper
  • MGC68935 Antikörper
  • ROMK Antikörper
  • romk1 Antikörper
  • Romk2 Antikörper
  • wu:fl37c05 Antikörper
  • zgc:63534 Antikörper

Bezeichner auf Proteinebene für KCNJ1

ATP-regulated potassium channel ROM-K , ATP-sensitive inward rectifier potassium channel 1 , inward rectifier K(+) channel Kir1.1 , inwardly rectifying K+ channel , potassium channel, inwardly rectifying subfamily J member 1 , potassium inwardly-rectifying channel, subfamily J, member 1 , potassium inwardly-rectifying channel J1 , ATP-sensitive inward rectifier potassium channel 1-like , K+ channel protein , KAB-1 , Potassium inwardly-rectifying channel subfamily J , kir1.1 , inwardly rectifying potassium channel ROMK-2 , potassium inwardly-rectifying channel, subfamily J, member 15 , LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1

GENE ID SPEZIES
3758 Homo sapiens
428236 Gallus gallus
447262 Xenopus laevis
466846 Pan troglodytes
489285 Canis lupus familiaris
539250 Bos taurus
714848 Macaca mulatta
100072580 Equus caballus
100173141 Pongo abelii
100470569 Ailuropoda melanoleuca
100487609 Xenopus (Silurana) tropicalis
100517668 Sus scrofa
100556003 Anolis carolinensis
100579741 Nomascus leucogenys
24521 Rattus norvegicus
56379 Mus musculus
379692 Xenopus laevis
386933 Danio rerio
100722828 Cavia porcellus
Ausgewählte Anbieter für anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) Antikörper
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