Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2) ELISA Kits

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Zusätzlich bieten wir Ihnen KCNN2 Antikörper (39) und und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
KCNN2 3781 Q9H2S1
Anti-Maus KCNN2 KCNN2 140492 P58390
Anti-Ratte KCNN2 KCNN2 54262 P70604
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Top KCNN2 ELISA Kits auf antikoerper-online.de

Showing 3 out of 7 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.059 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$648.42
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Human 0.059 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 8 bis 12 Tage
$840.25
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  10 reactions Anmelden zum Anzeigen 4 bis 6 Tage
$549.00
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Weitere ELISA Kits für KCNN2 Interaktionspartner

Human Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2) Interaktionspartner

  1. Study establishes the distribution profile of SK2 channel protein in human brain.The expression of SK2 human isoform b in brain could explain the variability of electrophysiological findings observed with SK2 channels.

  2. These results provide new insights into the regulation of SK2 channel trafficking by the cytoskeletal proteins FLNA (zeige FLNA ELISA Kits) and alpha-actinin2, involving distinct recycling pathways

  3. There was a significant association between the KCNN2 variants and clinically significant VTa. These findings suggest an association between KCNN2 and VTa; it also appears that KCNN2 variants may be adjunctive markers for risk stratification in patients susceptible to SCD (zeige SCD ELISA Kits).

  4. The ER SK2 channel activation preserves ER Ca(2 (zeige CA2 ELISA Kits)+) uptake and retention which determines cell survival in conditions where sustained ER stress contributes to progressive neuronal death.

  5. Differentiated dopaminergic neurons expressed low levels of SK2 channels and high levels of SK1 and SK3 channels.

  6. KCNN2 gene can have an important role in the development of coronary artery aneurysms in Kawasaki disease.

  7. Increase in both Ca(2 (zeige CA2 ELISA Kits)+) sensitivity and SK2 protein expression contributes to the IKAS upregulation in failing human ventricles.

  8. Decreased expression of small-conductance Ca2 (zeige CA2 ELISA Kits)+-activated K+ channels SK1 (zeige KCNN1 ELISA Kits) and SK2 in human chronic atrial fibrillation

  9. RT-PCR analysis showed strong expression of SK2 mRNA in the normal human colon.

  10. Because of the marked differential expression of SK2 channels in the heart, specific ligands for Ca2 (zeige CA2 ELISA Kits)+-activated K+ currents may offer a unique therapeutic opportunity to modify atrial cells without interfering with ventricular myocytes

Mouse (Murine) Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2) Interaktionspartner

  1. Probing the responsible cellular mechanisms pinpoints a disturbance in the expression and function of small-conductance Ca(2 (zeige CA2 ELISA Kits)+)-activated K(+) (SK) channels and reveals an important role for both SK2 (zeige PAPSS2 ELISA Kits) and SK3 (zeige KCNN3 ELISA Kits) channels in normal regulation of serotinin (5-HT (zeige DDC ELISA Kits)) neuronal excitability.

  2. SK2 (zeige PAPSS2 ELISA Kits) is nuclear in primary neurons and, unexpectedly, overexpressed SK2 (zeige PAPSS2 ELISA Kits) is neurotoxic in a dose-dependent manner.. We also found that SK2 (zeige PAPSS2 ELISA Kits) is hyperphosphorylated in the brain samples from a model of HD, the BACHD mice.Our results identify a novel regulator of mutant huntingtin (zeige HTT ELISA Kits)-mediated neurotoxicity and provide a new target for developing developing therapies for Huntington disease (zeige HTT ELISA Kits)

  3. Thus, MPP2 (zeige MPP2 ELISA Kits) is a novel synaptic scaffold that is required for proper synaptic localization and function of SK2 (zeige PAPSS2 ELISA Kits)-containing channels.

  4. Atrial SK2 and SK3 are significantly down-regulated from accelerated turnover in diabetic mice, resulting in action potential prolongation and arrhythmias.

  5. enhanced SK2 channel control over NMDAR contributes to LTP impairment via increased PP2A activity following context dependent sensitization to morphine.

  6. This study reveleated that outer hair cells of SK2 (zeige PAPSS2 ELISA Kits) knockout mice had few small efferent terminals. Synaptic cisterns were present, but smaller than those of wild-type littermates.

  7. SK2 and SK3 channels are expressed in different populations of motoneurons in rats and mice but not in cats

  8. Mitochondrial small conductance SK2 (zeige PAPSS2 ELISA Kits) channels prevent glutamate (zeige GRIN1 ELISA Kits)-induced oxytosis and mitochondrial dysfunction.

  9. Virtually all Cav2.1 (zeige CACNA1A ELISA Kits) clusters are colocalized in Purkinje cells with two types of calcium-activated potassium channels, SK2 (zeige PAPSS2 ELISA Kits) and BK.

  10. A developmental increase and gradient in SK2 (zeige PAPSS2 ELISA Kits)-containing channel surface expression is found that underlie the influence on neurotransmission.

KCNN2 Antigen-Profil

Beschreibung des Gens

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit KCNN2

  • potassium calcium-activated channel subfamily N member 2 (KCNN2) Antikörper
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 (Kcnn2) Antikörper
  • potassium calcium-activated channel subfamily N member 2 (Kcnn2) Antikörper
  • fri Antikörper
  • hSK2 Antikörper
  • KCa2.2 Antikörper
  • KCNN2 Antikörper
  • SK2 Antikörper
  • SKCA2 Antikörper
  • SKCa 2 Antikörper

Bezeichner auf Proteinebene für KCNN2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 , small conductance calcium-activated potassium channel protein 2 , small-conductance calcium-activated potassium channel , apamin-sensitive small-conductance Ca2+-activated potassium channel , small conductance potassium channel type 2 , SKCa 2 , small conductance calcium-activated potassium channel subfamily N member 2 , SK2 , SKCa2 , small conductance calcium-activated channel, subfamily N, member 2

GENE ID SPEZIES
695374 Macaca mulatta
100016183 Monodelphis domestica
100172000 Pongo abelii
100230275 Taeniopygia guttata
100589687 Nomascus leucogenys
395579 Gallus gallus
3781 Homo sapiens
474640 Canis lupus familiaris
404177 Bos taurus
140492 Mus musculus
54262 Rattus norvegicus
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