Potassium Channel Subfamily K Member 1 (KCNK1) ELISA Kits

KCNK1 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. Zusätzlich bieten wir Ihnen KCNK1 Antikörper (62) und KCNK1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human KCNK1 KCNK1 3775 O00180
Anti-Ratte KCNK1 KCNK1 59324 Q9Z2T2
Anti-Maus KCNK1 KCNK1 16525 O08581
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Weitere ELISA Kits für KCNK1 Interaktionspartner

Human Potassium Channel Subfamily K Member 1 (KCNK1) Interaktionspartner

  1. Dynamics of the TWIK-1 Channel

  2. Our data indicate that TWIK-1 has a highly conserved role in cardiac function and is required for normal heart rate and atrial morphology. Despite the functional importance of TWIK-1 in the atrium, genetic variation in KCNK1 is not a common primary cause of human AF.

  3. TWIK-1 protein possesses a hydrophobic barrier deep within the inner pore

  4. Potassium channels, in particular K2P channels, are expressed and functional in the apical membrane of airway epithelial cells

  5. study presents the 3.4 angstrom resolution crystal structure of a human K2P channel, K2P1; an extracellular cap domain located above the selectivity filter forms an ion pathway in which K(+) ions flow through side portals

  6. ion selectivity of TWIK-1 K+ channels during pathological hypokalemia; a molecular basis for inward leak Na+ currents that could trigger or contribute to cardiac paradoxical depolarization in lowered [K+]o; mechanism for regulating cardiac excitability.

  7. TWIK1 is internalized via a dynamin (zeige DNM1 ELISA Kits)-dependent mechanism and addressed to the recycling endosomal compartment. Mutation in its cytoplasmic C terminus (I293A,I294A) stabilizes TWIK1 at the plasma membrane, resulting in robust currents.

  8. Removal of the peptide adduct by SUMO protease reveals K2P1 to be a K+-selective, pH-sensitive, openly rectifying channel regulated by reversible peptide linkage.

  9. support TWIK-1 and TREK-1 (zeige KCNK2 ELISA Kits) as being the major components of the long-sought K(+) channels underlying the passive conductance of mature hippocampal astrocytes

Mouse (Murine) Potassium Channel Subfamily K Member 1 (KCNK1) Interaktionspartner

  1. KCNK1 was significantly induced during osteoclast differentiation, but its functional overexpression significantly inhibited osteoclast differentiation induced by RANKL (zeige TNFSF11 ELISA Kits)

  2. TWIK-1 is functionally expressed in dentate gyrus granule cells and contributes to the intrinsic excitability of these cells.

  3. TWIK-1/TREK-1 (zeige KCNK2 ELISA Kits) heterodimers mediate astrocytic passive conductance and cannabinoid-induced glutamate (zeige GRIN1 ELISA Kits) release from astrocytes.

  4. ion selectivity of TWIK-1 K+ channels during pathological hypokalemia; a molecular basis for inward leak Na+ currents that could trigger or contribute to cardiac paradoxical depolarization in lowered [K+]o; mechanism for regulating cardiac excitability.

  5. A fall in quinidine-sensitive conductance could be an adaptive response in TWIK-1 knockout ducts.

KCNK1 Antigen-Profil

Beschreibung des Gens

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.

Genbezeichner und Symbole assoziert mit KCNK1

  • potassium channel, subfamily K, member 1 (KCNK1) Antikörper
  • potassium channel, subfamily K, member 1 (Kcnk1) Antikörper
  • potassium channel, subfamily K, member 1 (kcnk1) Antikörper
  • AI788889 Antikörper
  • DPK Antikörper
  • HOHO Antikörper
  • K2P1 Antikörper
  • k2p1.1 Antikörper
  • KCNO1 Antikörper
  • rabKCNK1 Antikörper
  • Twik Antikörper
  • twik-1 Antikörper
  • twik1 Antikörper

Bezeichner auf Proteinebene für KCNK1

inward rectifying potassium channel protein TWIK-1 , potassium channel KCNO1 , potassium channel subfamily K member 1 , potassium inwardly-rectifying channel, subfamily K, member 1 , putative potassium channel TWIK , rTWIK , potassium channel TWIK-1

GENE ID SPEZIES
3775 Homo sapiens
59324 Rattus norvegicus
379125 Xenopus laevis
505563 Bos taurus
100008962 Oryctolagus cuniculus
16525 Mus musculus
100135567 Cavia porcellus
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