Potassium Channel, Subfamily K, Member 3 (KCNK3) ELISA Kits

KCNK3 encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. Zusätzlich bieten wir Ihnen Potassium Channel, Subfamily K, Member 3 Antikörper (93) und Potassium Channel, Subfamily K, Member 3 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human KCNK3 KCNK3 3777 O14649
Anti-Maus KCNK3 KCNK3 16527 O35111
Anti-Ratte KCNK3 KCNK3 29553 O54912
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Weitere ELISA Kits für Potassium Channel, Subfamily K, Member 3 Interaktionspartner

Human Potassium Channel, Subfamily K, Member 3 (KCNK3) Interaktionspartner

  1. our study indicates that TASK-1 is functionally regulated by caveolin-3 (zeige CAV3 ELISA Kits), possibly via association with each other on the cell surface. These results point out a novel mechanism in the regulation of TASK-1.

  2. A burden of rare variants in BMPR2 (zeige BMPR2 ELISA Kits) significantly contributed to the risk of pulmonary arterial hypertension. In the remaining one family, the patient carried a pathogenic variant in a member of potassium channels, KCNK3, which was the first replicative finding of channelopathy in an Asian population.

  3. The results suggested that heterodimerization of TASK1 and TALK2 provides cells with the ability to make multiple responses to a variety of physiological and pharmacological stimuli.

  4. Genetic variation in the KCNK3 gene may contribute to Blood pressure variation and less severe Hypertensive disorders in which aldosterone may be one of several causative factors

  5. Knockdown of TASK-1 by siRNA significantly enhanced apoptosis and reduced proliferation in Non-Small Cell Lung Cancer A549 cells, but not in weakly TASK-1 expressing NCI-H358 cells.

  6. The present report supports the contribution of KCNK3 mutations to the genetic etiology of Pulmonary arterial hypertension and strongly suggests that mutations in KCNK3 follow incomplete dominance with worsening of the clinical features in homozygous patients.

  7. In a cohort with idiopathic or hereditary pulmonary arterial hypertension, a possibly associated mutation was found in 11.10% of the idiopathic cases (n = 16) and in 68.18% of the hereditary cases. There were 3 mutations found in KCNK3.

  8. Functional alanine-mutagenesis screens of TASK-1 and TRAAK (zeige KCNK4 ELISA Kits) were used to build an in silico model of the TASK-1 cap.

  9. control of TASK-1 trafficking by COPI, kinases, phosphatases and 14-3-3 (zeige YWHAQ ELISA Kits) proteins is highly dynamic.

  10. KCNK3 expression and function were reduced in pulmonary artery smooth muscle cells and endothelial cells in human pulmonary arterial hypertension.

Mouse (Murine) Potassium Channel, Subfamily K, Member 3 (KCNK3) Interaktionspartner

  1. Adipose-specific Kcnk3 knockout mice display increased energy expenditure and are resistant to hypothermia and obesity.

  2. While there is compelling evidence that TASK-1 is involved in the pathogenesis of pulmonary arterial hypertension in humans, the mouse does not appear to serve as a suitable model to study the underlying molecular mechanisms

  3. the K(+) channel (zeige KCNC4 ELISA Kits) TASK1 controls the thermogenic activity in brown adipocytes through modulation of beta-adrenergic receptor signaling.

  4. KCNK3 channels are not involved in hearing.

  5. An important role for TASK-1 channels in limiting pancreatic alpha-cell excitability and glucagon (zeige GCG ELISA Kits) secretion during glucose stimulation.

  6. A glucose-dependent role for beta-cell TASK-1 channels of limiting glucose-stimulated Deltapsip depolarization and insulin (zeige INS ELISA Kits) secretion, which modulates glucose homeostasis.

  7. Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 (zeige KCNK9 ELISA Kits) channels in mouse carotid body type-1 cells.

  8. This study demonstrated for the first time that oligodendrocytes express functional TASK-1 channels and provide compelling evidence they contribute to oligodendrocyte damage in hypoxia.

  9. TASK-1 deficiency does neither alter key electrophysiological parameters nor increases atrial/ventricular vulnerability after electrical stimulation.

  10. The PCR data revealed the existence of two astrocytic subpopulations markedly differing in their gene expression levels for inwardly rectifying K+ channels (Kir4.1 (zeige KCNJ10 ELISA Kits)), K(2P) channels (TREK-1 (zeige KCNK2 ELISA Kits) and TWIK-1 (zeige KCNK1 ELISA Kits)) and Cl- channels (ClC2 (zeige CLCN2 ELISA Kits)).

Potassium Channel, Subfamily K, Member 3 (KCNK3) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.

Genbezeichner und Symbole assoziert mit KCNK3

  • potassium channel, subfamily K, member 3a (kcnk3a) Antikörper
  • potassium two pore domain channel subfamily K member 3 (KCNK3) Antikörper
  • potassium channel, subfamily K, member 3 (Kcnk3) Antikörper
  • potassium two pore domain channel subfamily K member 3 (Kcnk3) Antikörper
  • cTBAK-1 Antikörper
  • K2p3.1 Antikörper
  • KCNK3 Antikörper
  • OAT1 Antikörper
  • PPH4 Antikörper
  • rTASK Antikörper
  • si:dkey-164m15.1 Antikörper
  • TASK Antikörper
  • Task-1 Antikörper
  • TBAK1 Antikörper

Bezeichner auf Proteinebene für KCNK3

potassium channel subfamily K member 3 , TWIK-related acid-sensitive K(+) channel 1 , TWIK-related acid-sensitive K+ channel , acid-sensitive potassium channel protein TASK , acid-sensitive potassium channel protein TASK-1 , cardiac potassium channel , potassium inwardly-rectifying channel, subfamily K, member 3 , two P domain potassium channel , two pore K(+) channel KT3.1 , two pore potassium channel KT3.1 , cardiac two pore background K(+) channel , TASK-1 potassium channel

561866 Danio rerio
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428382 Gallus gallus
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