anti-Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Antikörper

POLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. Zusätzlich bieten wir Ihnen Polymerase (DNA Directed), gamma 2, Accessory Subunit Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
POLG2 303612  
POLG2 11232 Q9UHN1
POLG2 50776 Q9QZM2
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Top anti-Polymerase (DNA Directed), gamma 2, Accessory Subunit Antikörper auf antikoerper-online.de

Showing 10 out of 31 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using POLG2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB POLG2 Antibody (C-term) (ABIN1882118) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. POLG2 Antibody (C-term) (ABIN1882118) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-POLG2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal kidney 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Human Kaninchen Unkonjugiert IHC (p), ELISA 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: POLG2 Antibody [NBP1-83227] - Staining of human kidney shows strong cytoplasmic positivity in renal glomeruli while tubular cells are moderately stained. Western Blot: POLG2 Antibody [NBP1-83227] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cell lines, using POLG2 antibody. Immunofluorescence analysis of U2OS cell using POLG2 antibody. Blue: DAPI for nuclear staining. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Kaninchen Unkonjugiert IP, WB Immunoprecipitation of POLG2 transfected lysate using anti-POLG2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with POLG2 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of POLG2 expression in transfected 293T cell line by POLG2 MaxPab polyclonal antibody.<br><br>Lane 1: POLG2 transfected lysate(54.90 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μL Anmelden zum Anzeigen 7 bis 8 Tage
358,40 €
Details
Human Maus Unkonjugiert ELISA, WB Western Blot analysis of POLG2 expression in transfected 293T cell line by POLG2 monoclonal antibody (M01), clone 1A2.<br><br>Lane 1: POLG2 transfected lysate(54.9 KDa).<br>Lane 2: Non-transfected lysate.<br> Western Blot detection against Immunogen (79.09 KDa) . 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
443,50 €
Details

POLG2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Rat (Rattus)


Human , ,
,
,
Mouse (Murine)


Am meisten referenzierte anti-Polymerase (DNA Directed), gamma 2, Accessory Subunit Antikörper

  1. Human Polyclonal POLG2 Primary Antibody für FACS, IHC (p) - ABIN1882118 : Longley, Clark, Yu Wai Man, Hudson, Durham, Taylor, Nightingale, Turnbull, Copeland, Chinnery: Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia. in American journal of human genetics 2006 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Polymerase (DNA Directed), gamma 2, Accessory Subunit Interaktionspartner

Human Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Interaktionspartner

  1. This is the first report of a patient with a homozygous mutation in POLG2 and with a clinical presentation of severe hepatic failure and mitochondrial depletion.

  2. Results show that polymorphisms at POLG2 and POLRMT (zeige POLRMT Antikörper) increased risk of oral cancer and leukoplakia, respectively, probably modulating synthesis and activity of the enzymes.

  3. The authors describe the molecular characterization of a potential dominant POLG2 mutation (p.R369G) in a patient with autosomal dominant progressive external ophthalmoplegia and multiple mtDNA deletions.

  4. Data show that rs17650301 in POLG2 is a good candidate marker for UBC (zeige RPS27A Antikörper) invasiveness in Japanese males.

  5. The biochemical analysis helps explain the pathogenesis of POLG2 mutations in mitochondrial disease.

  6. human pol gammaB exhibits a catalytic subunit- and substrate DNA-dependent dimerization.

  7. PolB (zeige POLB Antikörper) gamma can bind double-stranded DNA and may play a role in DNA replication or repair

  8. Study represents the first structure-function analysis of the thumb subdomain in pol gamma (zeige POLG Antikörper) and examines the consequences of mitochondrial disease mutations in this region.

  9. Both increased and decreased expression of POLGbeta altered nucleoid structure and precipitated a marked decrease in 7S DNA molecules, which form short displacement-loops on mitochondrial DNA.

Mouse (Murine) Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Interaktionspartner

  1. Our data indicate that Polg2 function is critical to mammalian embryogenesis and mtDNA replication, and that a single copy of Polg2 is sufficient to sustain life.

Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2) Antigen-Profil

Protein Überblick

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

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Bezeichner auf Proteinebene für POLG2

DNA polymerase subunit gamma-2, mitochondrial , polymerase (DNA directed), gamma 2, accessory subunit , DNA polymerase subunit gamma-2, mitochondrial-like , DNA polymerase gamma accessory 55 kDa subunit , mitochondrial DNA polymerase accessory subunit , mitochondrial DNA polymerase subunit gamma-2 , mitochondrial DNA polymerase, accessory subunit , p55 , mitochondrial polymerase gamma 2 , mtPolB , polG-beta , polymerase, gamma 2

GENE ID SPEZIES
303612 Rattus norvegicus
417418 Gallus gallus
455266 Pan troglodytes
490910 Canis lupus familiaris
717856 Macaca mulatta
100029647 Monodelphis domestica
100064219 Equus caballus
100397872 Callithrix jacchus
100458861 Pongo abelii
100150674 Danio rerio
11232 Homo sapiens
50776 Mus musculus
505152 Bos taurus
398112 Xenopus laevis
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