Polycystic Kidney Disease 2-Like 1 Proteine (PKD2L1)

PKD2L1 encodes a member of the polycystin protein family. Zusätzlich bieten wir Ihnen PKD2L1 Antikörper (34) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PKD2L1 329064  
PKD2L1 9033 Q9P0L9
Ratte PKD2L1 PKD2L1 293937  
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Showing 5 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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PKD2L1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,
,
Human , ,
, ,

Weitere Proteine zu Polycystic Kidney Disease 2-Like 1 (PKD2L1) Interaktionspartnern

Mouse (Murine) Polycystic Kidney Disease 2-Like 1 (PKD2L1) Interaktionspartner

  1. In epileptic seizures mouse model, Pkdl deficiency leads to the loss of beta2AR (zeige ADRB2 Proteine) on neuronal cilia, reduction in cAMP levels in the central nervous system, and reduction in the activation of cAMP response element-binding protein.

  2. This study demonstrated that spontaneously active unitary currents in CSF (zeige CSF2 Proteine)-cNs are due to PKD2L1 channels that are capable, with a single opening, of triggering action potentials

  3. sour taste cells in the posterior tongue express a proton current; the current is present in PKD2L1-expressing taste cells from circumvallate, foliate, and fungiform papillae but not in a variety of other cells

  4. findings suggest that PKD2L1 partly contributes to sour taste responses in mice and that receptors other than PKDs would be involved in sour detection

  5. All channel-forming isoforms of TRPP channels (polycystin-2 (zeige PKD2 Proteine), polycystin-L, and polycystin-2L2 (zeige PKD2L2 Proteine)) were expressed in adult mouse lacrimal gland.

  6. These results demonstrate that Asp (zeige C3 Proteine)(523) in PKD2L1 is a key determinant of Ca(2 (zeige CA2 Proteine)+) permeation into the PKD1L3 (zeige PKD1L3 Proteine)/PKD2L1 complex and that PKD2L1 contributes to forming the pore of the PKD1L3 (zeige PKD1L3 Proteine)/PKD2L1 channel.

  7. the PKD2L1-PKD1L3 (zeige PKD1L3 Proteine) complex is involved in acid sensing in vivo

  8. PKD2L1 forms functional cation channels on the plasma membrane by interacting with PKD1 (zeige PKD1 Proteine)

  9. Pkd1l3 (zeige PKD1L3 Proteine) and Pkd2l1 are co-expressed in a select subset of taste receptor cells and therefore may, like other PKD (zeige PRKD1 Proteine) channels, function as a heteromer.

  10. These results suggest that PKD1L3 (zeige PKD1L3 Proteine) and PKD2L1 heteromers may function as sour taste receptors.

Human Polycystic Kidney Disease 2-Like 1 (PKD2L1) Interaktionspartner

  1. palmitoylation at Cys (zeige DNAJC5 Proteine)-38 and phosphorylation at Thr (zeige TRH Proteine)-39 independently regulated TRPP3 channel function

  2. our study identified C1 as the first PKD2L1 domain essential for both PKD2L1 trimerization and channel function, and suggest that PKD2L1 and PKD2L1/PKD1L3 (zeige PKD1L3 Proteine) channels share the PKD2L1 trimerization process.

  3. Trimerization may be important for both homo- and possibly heteromeric assemblies of PKD2L1.

  4. This study demonistrated that human PKD2L play the role of food preference behavior.

  5. Pkd2L1 is a novel target channel whose function is regulated by the versatile scaffolding protein RACK1 (zeige GNB2L1 Proteine).

  6. Despite the moderate sequence identity between C-terminal regulatory domains (CRDs) of PKD2 (zeige PKD2 Proteine) and PKD2L1, they both form trimers, implying that trimeric organization of CRDs may be true of all polycystin channels.

  7. the PKD2L1-PKD1L3 (zeige PKD1L3 Proteine) complex is involved in acid sensing in vivo

  8. The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation.

  9. Taken together, alpha-actinin (zeige ACTN1 Proteine) not only attaches TRPP3 to the cytoskeleton but also up-regulates TRPP3 channel function.

PKD2L1 Protein Überblick

Protein Überblick

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PKD2L1

  • polycystic kidney disease 2-like 1 (PKD2L1)
  • polycystic kidney disease 2-like 1 (pkd2l1)
  • polycystic kidney disease 2-like 1 (Pkd2l1)
  • B830002B15 Protein
  • BC046386 Protein
  • PCL Protein
  • PKD2L Protein
  • PKD2L1 Protein
  • PKDL Protein
  • si:packtrz.2 Protein
  • si:xx-packtrz.2 Protein
  • TRPP3 Protein

Bezeichner auf Proteinebene für PKD2L1

polycystic kidney disease 2-like 1 , polycystic kidney disease 2-like 1 protein-like , polycystin-L , polycystic kidney disease 2-like 1 protein , polycystin-2 homolog , polycystin-2L1 , polycystin-L1 , transient receptor potential cation channel, subfamily P, member 3

GENE ID SPEZIES
428954 Gallus gallus
466255 Pan troglodytes
486838 Canis lupus familiaris
521231 Bos taurus
567026 Danio rerio
100027906 Monodelphis domestica
100070385 Equus caballus
100467173 Ailuropoda melanoleuca
100495064 Xenopus (Silurana) tropicalis
100545372 Meleagris gallopavo
100564081 Anolis carolinensis
100596906 Nomascus leucogenys
329064 Mus musculus
9033 Homo sapiens
293937 Rattus norvegicus
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