anti-Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) Antikörper

p53/TP53-regulated repressor of Akt/AKT1 signaling. Zusätzlich bieten wir Ihnen PHLDA3 Proteine (6) und PHLDA3 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PHLDA3 23612 Q9Y5J5
PHLDA3 27280 Q9WV95
PHLDA3 363989 Q5PQT7
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Top anti-PHLDA3 Antikörper auf antikoerper-online.de

Showing 10 out of 32 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Meerschweinchen Kaninchen Unkonjugiert WB WB Suggested Anti-PHLDA3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: 293T cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Maus Unkonjugiert WB 100 μg Anmelden zum Anzeigen 5 bis 7 Tage
413,81 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PHLDA3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Hamster Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
722,86 €
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of PHLDA3 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wit Western blot analysis of PHLDA3 expression in HEK293T (A) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
505,48 €
Details

PHLDA3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PHLDA3 Antikörper

  1. Human Monoclonal PHLDA3 Primary Antibody für WB - ABIN2452076 : Kawase, Ohki, Shibata, Tsutsumi, Kamimura, Inazawa, Ohta, Ichikawa, Aburatani, Tashiro, Taya: PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt. in Cell 2009 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen PHLDA3 Interaktionspartner

Human Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) Interaktionspartner

  1. Low PHLDA3 expression in ESCC may be predictive of tumor recurrence suggesting that Akt (zeige AKT1 Antikörper) activation may be a therapeutic target in ESCCs

  2. Results indicate that tumor suppressor PHLDA3-mediated pathway is important in the development of pancreatic neuroendocrine tumors (PanNETs).

  3. findings indicate somatic mutation of PHLDA3 is rare in common cancer types; PHLDA3 expression was lost in 22% of prostate cancers; these results indicate that PHLDA3 are altered in prostate cancers by loss of expression

  4. Study identifies PHLDA3 as a p53 (zeige TP53 Antikörper) target gene that encodes a PH domain-only protein and finds that PHLDA3 competes with the PH domain of Akt (zeige AKT1 Antikörper) for binding of membrane lipids, inhibiting Akt (zeige AKT1 Antikörper) translocation to the cellular membrane and activation.

Mouse (Murine) Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3) Interaktionspartner

  1. Phlda3 may cause p53 (zeige TP53 Antikörper) accumulation through a feedforward pathway, facilitating tubular injury and its urine excretion.

  2. Data indicate that tumor suppressor PHLDA3-deficient mice develop islet hyperplasia.

  3. Ipl (zeige PHLDA2 Antikörper) and Tih1 are bona fide PH domain proteins, with broad specificity and moderate affinity for PIPs (zeige GPRASP1 Antikörper).

PHLDA3 Antigen-Profil

Protein Überblick

p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor (By similarity).

Genbezeichner und Symbole assoziert mit PHLDA3

  • pleckstrin homology-like domain, family A, member 3 (PHLDA3) Antikörper
  • pleckstrin homology-like domain, family A, member 3 (Phlda3) Antikörper
  • pleckstrin homology-like domain, family A, member 3 (phlda3) Antikörper
  • si:dz182n13.5 Antikörper
  • Tih1 Antikörper
  • zgc:92333 Antikörper

Bezeichner auf Proteinebene für PHLDA3

pleckstrin homology-like domain, family A, member 3 , TDAG51/Ipl homolog 1 , pleckstrin homology-like domain family A member 3 , pleckstrin homology-like domain, family A, member 2 , TDAG/lpl homolog 1

GENE ID SPEZIES
457620 Pan troglodytes
23612 Homo sapiens
27280 Mus musculus
363989 Rattus norvegicus
368779 Danio rerio
Ausgewählte Anbieter für anti-PHLDA3 (PHLDA3) Antikörper
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