Plastin 3 (PLS3) ELISA Kits

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. Zusätzlich bieten wir Ihnen Plastin 3 Antikörper (61) und Plastin 3 Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human PLS3 PLS3 5358 P13797
Anti-Ratte PLS3 PLS3 81748  
Anti-Maus PLS3 PLS3 102866 Q99K51
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Weitere ELISA Kits für Plastin 3 Interaktionspartner

Human Plastin 3 (PLS3) Interaktionspartner

  1. PLS3 mutation plays a role in low turnover osteoporosis pathophysiology.

  2. In this study, the authors found that the actin filament bundling abilities of PLS1 (zeige PLS1 ELISA Kits) and PLS2 (zeige LCP1 ELISA Kits) were similarly sensitive to Ca(2 (zeige CA2 ELISA Kits)+) (pCa50 ~6.4), whereas PLS3 was less sensitive (pCa50 ~5.9).

  3. Patients with PLS3 mutation-related osteoporosis respond to teriparatide treatment.

  4. We show that genes of the classical apoptosis pathway are involved in the smn-1 (zeige SMN1 ELISA Kits)-mediated neuronal death, and that this phenotype can be rescued by the expression of human SMN1 (zeige SMN1 ELISA Kits), indicating a functional conservation between the two orthologs. Finally, we determined that Plastin3/plst-1 genetically interacts with smn-1 (zeige SMN1 ELISA Kits) to prevent degeneration, and that treatment with valproic acid is able to rescue the degenerative phenotype

  5. PLS3 expression does not always modify SMA (zeige SMN1 ELISA Kits) phenotype

  6. findings emphasize the power of genetic modifiers, PLS3 and CORO1C (zeige CORO1C ELISA Kits), to unravel the cellular pathomechanisms underlying spinal muscular atrophy (SMA (zeige SMN1 ELISA Kits))--and the power of combinatorial therapy based on splice correction of SMN2 (zeige SMN1 ELISA Kits) and endocytosis improvement to efficiently treat SMA (zeige SMN1 ELISA Kits)

  7. PLS3 is a genuine spinal muscular atrophy protective modifier in SMN1 (zeige SMN1 ELISA Kits)-deleted individuals

  8. Measurements of SMN (zeige STMN1 ELISA Kits) and PLS3 transcript and protein levels in induced pluripotent stem cell-derived motor neurons show limited value as Spinal muscular atrophy biomarkers.

  9. High levels of recombinant hPLS3 mRNA were expressed in motor neurons of SMA (zeige SMN1 ELISA Kits) mice and an increased level of PLS3 protein in total spinal cord, yet neither survival nor the fundamental electrophysiological aspects of the neuromuscular junction improved.

  10. results confirm the role of PLS3 mutations in early onset osteoporosis. The mechanism whereby PLS3 affects bone health is unclear, but it may be linked to osteocyte dendrite function and skeletal mechanosensing

Plastin 3 (PLS3) Antigen-Profil

Beschreibung des Gens

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit Plastin 3 (PLS3) ELISA Kits

  • plastin 3 (pls3) Antikörper
  • plastin 3 (PLS3) Antikörper
  • plastin 3 (T isoform) (pls3) Antikörper
  • plastin 3 (Pls3) Antikörper
  • plastin 3 (T-isoform) (Pls3) Antikörper
  • T-plastin (LOC100689375) Antikörper
  • AI115446 Antikörper
  • AL024105 Antikörper
  • DKFZp459D0939 Antikörper
  • MGC68681 Antikörper
  • MGC106020 Antikörper
  • Plastin-3 Antikörper
  • PLS3 Antikörper
  • T-fimbrin Antikörper
  • T-plastin Antikörper

Bezeichner auf Proteinebene für Plastin 3 (PLS3) ELISA Kits

plastin 3 , plastin 3 (T isoform) , plastin-3 , plastin-3-like , T fimbrin , T plastin , T-plastin , plastin 3 (T-isoform) , plastin 3, T

GENE ID SPEZIES
399002 Xenopus laevis
465817 Pan troglodytes
481025 Canis lupus familiaris
595091 Xenopus (Silurana) tropicalis
709055 Macaca mulatta
100053927 Equus caballus
100158187 Sus scrofa
100172754 Pongo abelii
100403677 Callithrix jacchus
100475279 Ailuropoda melanoleuca
100545275 Meleagris gallopavo
100602943 Nomascus leucogenys
5358 Homo sapiens
81748 Rattus norvegicus
505687 Bos taurus
102866 Mus musculus
100689375 Cricetulus griseus
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