Plakophilin 1 Proteine (PKP1)

PKP1 encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Zusätzlich bieten wir Ihnen Plakophilin 1 Antikörper (52) und Plakophilin 1 Kits (26) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PKP1 18772 P97350
Ratte PKP1 PKP1 304822  
PKP1 5317 Q13835
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 66 Days
10.536,00 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
682,86 €
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PKP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , , ,
, , ,

Weitere Proteine zu Plakophilin 1 (PKP1) Interaktionspartnern

Mouse (Murine) Plakophilin 1 (PKP1) Interaktionspartner

  1. PKP1 has roles in desmosome and tight junction function and in growth control, a function that is crucial in wound healing and epidermal carcinogenesis

  2. This approach identified a key signaling event, phosphorylation of a desmosome component, PKP1 (plakophilin-1) by RIPK4 (receptor-interacting serine-threonine kinase 4 (zeige RIPK4 Proteine)) during epidermal differentiation.

Human Plakophilin 1 (PKP1) Interaktionspartner

  1. These results implicate the participation of PKP1 in early tooth morphogenesis as an effector of canonical Wnt (zeige WNT2 Proteine) signaling that controls ameloblast differentiation via regulation of the cell adhesion complex

  2. Collectively, altered expression of PKP1 and SPOCK1 (zeige SPOCK1 Proteine) appears to be a frequent and critical event in prostate cancer

  3. cytoplasmic PKP1/3 are components of mRNA ribonucleoprotein particles and act as posttranscriptional regulators of gene expression.

  4. Plakophilin-1 has a role in protecting keratinocytes from pemphigus vulgaris (zeige DSG3 Proteine) IgG by forming calcium-independent desmosomes

  5. Data indicate that upon activation of growth factor signaling, plakophilin 1 switches from a desmosome-associated growth-inhibiting to a cytoplasmic proliferation-promoting function.

  6. In breast cancer, compared with normal tissue, PKP1 and PKP2 expressions were indifferent (P > 0.05), but PKP3 (zeige PKP3 Proteine) expression was significantly increased

  7. PKP1 loss secondary to promoter methylation, as well as other mechanisms, may promote the progression of Barrett's esophagus to esophageal adenocarcinoma in a subset of patients via decreased desmosome assembly and increased cell motility

  8. both loss of PKP1 and up-regulation of PKP3 (zeige PKP3 Proteine) expression are biologically important events in prostate cancer and are associated with a more aggressive phenotype

  9. These findings identify PKP1 as a regulator of translation and proliferation via modulation of eIF4A1 (zeige EIF4A1 Proteine) activity.

  10. the clinicopathologic features attest to the significant role of PKP1 in stabilization of desmosome structure and function, predominantly in the spinous layers of the epidermis

Plakophilin 1 (PKP1) Protein Überblick

Protein Überblick

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Plakophilin 1 Proteine (PKP1)

  • plakophilin 1 (PKP1)
  • plakophilin 1 (pkp1)
  • plakophilin 1 (Pkp1)
  • plakophilin 1 (LOC100338080)
  • plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) (PKP1)
  • plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) (Pkp1)
  • AI528551 Protein
  • B6P Protein
  • fb30d08 Protein
  • PKP1 Protein
  • wu:fb30d08 Protein

Bezeichner auf Proteinebene für Plakophilin 1 Proteine (PKP1)

plakophilin 1 , plakophilin-1 , band 6 protein , B6P , armadillo , band 6 , band-6 protein

GENE ID SPEZIES
708177 Macaca mulatta
797838 Danio rerio
18772 Mus musculus
304822 Rattus norvegicus
100338080 Oryctolagus cuniculus
421158 Gallus gallus
5317 Homo sapiens
281405 Bos taurus
100733998 Cavia porcellus
101109291 Ovis aries
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