anti-Pituitary Tumor-Transforming 1 (PTTG1) Antikörper

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. Zusätzlich bieten wir Ihnen PTTG1 Proteine (15) und PTTG1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PTTG1 9232 O95997
PTTG1 64193 P97613
PTTG1 30939 Q9CQJ7
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Top anti-PTTG1 Antikörper auf antikoerper-online.de

Showing 10 out of 77 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Western blot analysis of PTTG1 antibody (N-term) (ABIN391532) in Ramos cell line lysates (35 µg/lane). PTTG1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue with PTTG1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from HepG2/Jurkat/293 cells, using PTTG1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HuvEc cells, using PTTG1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from RAW264.7 cells, using PTTG Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PTTG Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Ziege Unkonjugiert IHC (p) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
385,00 €
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Human Maus Unkonjugiert IF, IHC (p), IP, WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
396,00 €
Details
Human Kaninchen Unkonjugiert WB Anti-Securin antibody, Western blotting All lanes: Anti PTTG1  at 0.5ug/ml Lane 1: HELA Whole Cell Lysate at 40ug Lane 2: MCF-7 Whole Cell Lysate at 40ug Lane 3: SKOV Whole Cell Lysate at 40ug Lane 4: A375 Whole Cell Lysate at 40ug Predicted bind size: 22KD Observed bind size: 22KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Ziege Unkonjugiert IHC (p) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
517,00 €
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Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
635,55 €
Details
Human Maus Unkonjugiert IHC (p), IHC Formalin-fixed, paraffin-embedded human tonsil stained with ABIN153436 using peroxidase-conjugate and AEC chromogen. Note nuclear staining of lympocytes in germinal center. Immunohistochemistry-Paraffin: Securin Antibody (DCS-280) [ABIN153436] - Human tonsil stained with NB 600-549 using peroxidase-conjugate and AEC chromogen. Note nuclear staining of lympocytes in germinal center. 0.5 mL Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
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PTTG1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
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Am meisten referenzierte anti-PTTG1 Antikörper

  1. Human Polyclonal PTTG1 Primary Antibody für IF, IHC (p) - ABIN391532 : Cui, Xu, Song, Zhao, Liu, Song: Pituitary tumor transforming gene: a novel therapeutic target for glioma treatment. in Acta biochimica et biophysica Sinica 2015 (PubMed)

Weitere Antikörper gegen PTTG1 Interaktionspartner

Human Pituitary Tumor-Transforming 1 (PTTG1) Interaktionspartner

  1. Findings indicate that PBF (zeige PTTG1IP Antikörper) and PTTG have a critical role in promoting thyroid cancer that is predictive of poorer patient outcome.

  2. PTTG-mediated FGF2 (zeige FGF2 Antikörper) upregulation is associated with more aggressive tumor features in patients with acromegaly. Also, locally produced estrogen through aromatization might have a role in this phenomenon.

  3. All these suggest that the MAP3K M1P site is a potential interacting partner of MAP3K SH3 domain (zeige ITSN1 Antikörper), which may mediate the intermolecular recognition between hPTTG1 and MAP3K.

  4. that PTTG1 is a novel downstream target gene of androgen receptor (zeige AR Antikörper) and take part in prostate cancer proliferation and metastasis

  5. Knockdown of PTTG1 suppresses the growth and invasion of LAC (zeige LCT Antikörper) cells through upregulation of the TGFbeta1 (zeige TGFB1 Antikörper)/SMAD3 (zeige SMAD3 Antikörper) signaling.

  6. PTTG1 is correlated with non-small cell lung cancer (NSCLC) progression and as an independent poor prognostic factor in NSCLC patients.

  7. Our data indicate that securin expression may serve as a strong and independent prognosticator of breast cancer outcome

  8. PTTG1 mRNA expression levels in gastric tumor tissues were significantly higher than in the corresponding adjacent normal gastric mucosa.PTTG1 mRNA and protein expression are independent prognostic factors for gastric cancer patient survival.

  9. Pttg1 may increase BC cell growth through nuclear exclusion of p27 (zeige PAK2 Antikörper), which highlights a novel molecular regulatory machinery in tumorigenesis of BC.

  10. Data show that overexpression of c-myc proto-oncogene (zeige MYC Antikörper) protein (zeige MYC Antikörper) could prevent the metabolic shift induced by pituitary tumor-transforming gene (PTTG) knockwown.

Pig (Porcine) Pituitary Tumor-Transforming 1 (PTTG1) Interaktionspartner

  1. PTTG1 is a new candidate maternal effect (zeige NLRP5 Antikörper) gene that may participate in the processes of oocyte maturation and zygotic genome activation during embryogenesis

Mouse (Murine) Pituitary Tumor-Transforming 1 (PTTG1) Interaktionspartner

  1. High PTTG1 expression is associated with pituitary tumor development.

  2. PTTG is functionally required for hepatic fibrosis progression in an animal model of chronic liver injury, and thus a potential treatment target.

  3. RasGrf1 (zeige RASGRF1 Antikörper) is an important upstream component of signal transduction pathways regulating Pttg1 expression and controlling beta cell development and physiological responses.

  4. these results implicate Pttg1 in the regulation of homotypic spacing between specific types of retinal neurons.

  5. Pttg1/securin has roles in branching morphogenesis of the mammary gland and suppression of mammary tumorigenesis

  6. PBF (zeige PTTG1IP Antikörper) is the first protein to interact with the critical TH transporter MCT8 (zeige MCT8 Antikörper) and modulate its function in vivo

  7. CSN3 (zeige CSN3 Antikörper) and CSN5 (zeige COPS5 Antikörper) are involved in oocyte meiosis by regulating degradation of Cyclin B1 (zeige CCNB1 Antikörper) and Securin via APC (zeige APC Antikörper)/C.

  8. The genetically deleting Tff3 in mice altered down-regulated Pttg1 and up-regulated serpina3n expression, indicating a potential role of these factors during the development of presbyacusis.

  9. data reveal that up to 9 months of age, Pttg1(-/-) retinas have a healthy morphology and normal photoreceptor function

  10. Pituitary tumor transforming gene 1 (PTTG1), an oncogene (zeige RAB1A Antikörper), was the most up-regulated transcript in KLF6 (zeige KLF6 Antikörper)+/- liver. PTTG1 downregulation represents a novel tumor suppressor pathway of KLF6 (zeige KLF6 Antikörper).

PTTG1 Antigen-Profil

Protein Überblick

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.

Genbezeichner und Symbole assoziert mit PTTG1

  • pituitary tumor-transforming 1 (PTTG1) Antikörper
  • pituitary tumor-transforming 1 (Pttg1) Antikörper
  • pituitary tumor-transforming gene 1 (Pttg1) Antikörper
  • AW555095 Antikörper
  • C87862 Antikörper
  • EAP1 Antikörper
  • HPTTG Antikörper
  • Pttg Antikörper
  • PTTG1 Antikörper
  • Pttg3 Antikörper
  • Securin Antikörper
  • TUTR1 Antikörper

Bezeichner auf Proteinebene für PTTG1

pituitary tumor-transforming protein 1 , securin , pituitary tumor-transforming 1 , ESP1-associated protein 1 , pituitary tumor-transforming gene 1 protein , tumor-transforming protein 1 , Pituitary tumor transforming

GENE ID SPEZIES
416158 Gallus gallus
479307 Canis lupus familiaris
510673 Bos taurus
539883 Bos taurus
696143 Macaca mulatta
9232 Homo sapiens
64193 Rattus norvegicus
397015 Sus scrofa
508043 Bos taurus
462238 Pan troglodytes
30939 Mus musculus
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