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The protein encoded by PPAP2B is a member of the phosphatidic acid phosphatase (PAP) family. Zusätzlich bieten wir Ihnen PPAP2B Proteine (1) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 31 products:
LPP3 is a negative regulator of inflammatory cytokines, leucocyte adhesion, cell survival, and migration in HAECs, suggesting a protective role of LPP3 against endothelial dysfunction.
Data show gender-related differences in the association between phosphatidic acid phosphatase type 2B (PPAP2B) gene single nucleotide polymorphisms (SNPs) and coronary heart disease (CHD (zeige CHDH Antikörper)) susceptibility in the Chinese Han population.
Mechanosensitive PPAP2B plays a critical role in promoting anti-inflammatory phenotype and maintaining vascular integrity of endothelial monolayer under atheroprotective flow.
study concludes polymorphisms of TGM5 (zeige TGM5 Antikörper), PPAP2B and PSMA4 (zeige PSMA4 Antikörper) are not major contributors tonon-small cell lung cancer susceptibility in never-smoking hinese population, this primarily can be attributed to the significantly distinct genetic background of Asian populations from western populations
PPAP2B gene rearrangement is associated with lipomas.
expression of LPP3 in human colon tumor (SW480) cells potentiated tumor growth via increased beta-catenin (zeige CTNNB1 Antikörper) stability and CYCLIN-D1 (zeige CCND1 Antikörper) synthesis
Results identify a key role for LPP3 in orchestrating PTEN (zeige PTEN Antikörper)-mediated beta-catenin (zeige CTNNB1 Antikörper)/LEF-1 (zeige LEF1 Antikörper) signaling in EC migration, cell-cell adhesion, and formation of branching point structures.
there are marked differences in biochemical activity between fly Wun (zeige PPAP2A Antikörper) and mammalian lipid phosphate phosphatase (LPPs), with Wun (zeige PPAP2A Antikörper) having a narrower activity range than has been reported for the mammalian LPPs
LPP1 (zeige PPAP2A Antikörper) and LPP3 are distributed in distinct lipid rafts that may provide unique microenvironments defining their non-redundant physiological functions.
LPP3 acted as an ecto (zeige TRIM33 Antikörper)-phosphatase on FTY720-P.
Demonstrate essential roles of LPP3 in the maturation of endothelial cell barrier integrity and normal cardiovascular development.
Results identify a role for the autotaxin (zeige ENPP2 Antikörper)/LPA-signaling nexus as a mediator of endothelial permeability in inflammation and demonstrate that LPP3 limits these effects.
LPP3 serves as an intrinsic negative regulator of smooth muscle cell phenotypic modulation and inflammation after vascular injury, in part, by regulating lysophospholipid signaling.
Our data show that LPP3 plays a fundamental role during spinal neuron differentiation from embryonic stem cells and that it also participates in regulating neurite and axon outgrowth.
generation and destruction are tightly regulated and LPP3 is essential to establish the balance
Altogether our data indicate that LPP3 participates in several aspects of neuron-glia communication required for proper cerebellum development.
Data show that mouse embryos deficient for lipid phosphate phosphatase 3 fail to form a chorio-allantoic placenta and yolk sac (zeige ADCY10 Antikörper) vasculature.
provide a mechanism for the function of LPP3 in cell-cell interactions in both human and mouse
Lpp3 expression may play a key role in modulating/integrating multiple signaling pathways during development
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells.
lipid phosphate phosphohydrolase 3
, phosphatidic acid phosphatase type 2B
, PAP2 beta
, phosphatidate phosphohydrolase type 2b
, type-2 phosphatidic acid phosphatase-beta
, vascular endothelial growth factor and type I collagen inducible
, phosphatidic acid phosphatase 2b
, ER transmembrane protein Dri 42
, differentially expressed in rat intestine 42