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PES1 encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. Zusätzlich bieten wir Ihnen PES1 Antikörper (38) und PES1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
PES1 may play an important role in development of gastric cancer.
The DDX27 (zeige DDX27 ELISA Kits) can interact specifically with the Pes1 and Bop1 (zeige BOP1 ELISA Kits) but fulfils critical function(s) for proper 3' end formation of 47S rRNA independently of the PeBoW-complex.
PES1 may play important role in the progression of ovarian cancer by inversely regulating the ERalpha (zeige ESR1 ELISA Kits) and ERbeta (zeige ESR2 ELISA Kits) expression.
these results uncover a potential role of PES1 in chemoresistance by regulating DNA damage response in colorectal cancer cells.
Upstream of c-Jun (zeige JUN ELISA Kits), it was revealed that c-Jun (zeige JUN ELISA Kits) NH2-terminal kinases (JNK (zeige MAPK8 ELISA Kits)) is essential for controlling PES1 expression
expression of PES1 correlated positively with ERalpha (zeige ESR1 ELISA Kits) expression and negatively with ERbeta (zeige ESR2 ELISA Kits) expression and predicted good clinical outcome in breast cancer
The physical interaction between B23 (zeige NPM1 ELISA Kits) and PES1 implies that they may participate in ribosome biogenesis in a protein complex.
pescadillo might play a role in promoting the proliferation and carcinogenesis of human breast cancer, and thereby might be a potential target for human breast cancer treatment.
Mechanisms for the ability of Pes1 to transform cells, and its failure to immortalize them.
RRB1 (zeige GRWD1 ELISA Kits) interacts with YPH1 (yeast pescadillo homologue 1) and other members of the Yph1 complex
These data suggest that PES1 is a marker of neuroblastoma (zeige ARHGEF16 ELISA Kits) outcome, that it regulates neuroblastoma (zeige ARHGEF16 ELISA Kits) cell proliferation, and is associated with neuroblastoma (zeige ARHGEF16 ELISA Kits) differentiation.
Data show that pescadillo associates with several structures that are associated with nucleogenesis, and that loss of function results in embryonic lethality due to disrupted ribosome biosynthesis.
effects of PES1 and UBF1 (zeige UBTF ELISA Kits) expression on the growth and differentiation of cell lines derived from 32D cells, an interleukin-3 (IL-3 (zeige IL-3 ELISA Kits))-dependent murine myeloid cell line
Interaction with Bop1 (zeige BOP1 ELISA Kits) is essential for the efficient incorporation of Pes1 into nucleolar preribosomal complexes.
Mtap1b (zeige MAP1B ELISA Kits)-Light chain 1 has the potential to repress cell proliferation by modulating the nucleolar levels of Pes1
pes1 and ppan (zeige PPAN ELISA Kits) are required for Xenopus pronephros development and indicate that their function in the pronephros is independent of their role in ribosome biosynthesis
pescadillo has multiple important functions during X. laevis development; pescadillo is required for eye development and neural crest migration
This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
, pescadillo homolog 1, containing BRCT domain