anti-Peroxisomal Biogenesis Factor 3 (PEX3) Antikörper

The product of PEX3 is involved in peroxisome biosynthesis and integrity. Zusätzlich bieten wir Ihnen PEX3 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PEX3 8504 P56589
PEX3 56535 Q9QXY9
PEX3 83519 Q9JJK4
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Top anti-PEX3 Antikörper auf antikoerper-online.de

Showing 10 out of 23 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HeLa cells, using PEX3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: PEX3 Antibody [NBP1-86210] - Staining of human kidney shows strong cytoplasmic positivity in cells of tubules. Immunocytochemistry/Immunofluorescence: PEX3 Antibody [NBP1-86210] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & vesicles. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$175.80
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Western blot analysis of PEX3 expression in HEK293T (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Hund Kaninchen Unkonjugiert IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$343.75
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$478.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: PEX3 Antibody [NBP1-52960] - Titration: 5.0ug/ml Positive Control: HepG2 cell lysate. Immunohistochemistry-Paraffin: PEX3 Antibody [NBP1-52960] - Human Liver Tissue, antibody concentration 4-8ug/ml. Cells with positive label: Hepatocytes (indicated with arrows) 400X magnification. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$408.19
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of mouse liver, using PEX3 antibody. Immunohistochemistry of paraffin-embedded human liver injury using PEX3 antibody at dilution of 1:100 (x40 lens). 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details

PEX3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human ,
,
,
Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-PEX3 Antikörper

  1. Human Polyclonal PEX3 Primary Antibody für ICC, IF - ABIN4344976 : Sychev, Hu, DiMaio, Gitter, Camp, Noble, Wolf-Yadlin, Lagunoff: Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism. in PLoS pathogens 2017 (PubMed)

  2. Cow (Bovine) Polyclonal PEX3 Primary Antibody für IHC, WB - ABIN2782478 : Fang, Morrell, Jones, Gould: PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins. in The Journal of cell biology 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen PEX3 Interaktionspartner

Human Peroxisomal Biogenesis Factor 3 (PEX3) Interaktionspartner

  1. that newly synthesized UBXD8 (zeige FAF2 Antikörper) is post-translationally inserted into discrete ER subdomains by a mechanism requiring cytosolic PEX19 (zeige PEX19 Antikörper) and membrane-integrated PEX3, proteins hitherto exclusively implicated in peroxisome biogenesis

  2. This insertion of PEX3 into the ER is physiologically relevant.

  3. PEX16 (zeige PEX16 Antikörper) mediates the peroxisomal trafficking of two distinct peroxisomal membrane proteins, PEX3 and PMP34 (zeige SLC25A17 Antikörper), via the endoplasmic reticulum

  4. Thus within the cell, PEX3 is stabilized by PEX19 (zeige PEX19 Antikörper) preventing PEX3 aggregation.

  5. Mutations in the PEX19 (zeige PEX19 Antikörper)-binding domain of PEX3 reduce the affinity for PEX19 (zeige PEX19 Antikörper) and destabilize PEX3.

  6. The crystal structure of the cytosolic domain of PEX3 in complex with a PEX19 (zeige PEX19 Antikörper)-derived peptide. PEX3 adopts a novel fold that is best described as a large helical bundle.

  7. Interaction of PEX3 and PEX19 (zeige PEX19 Antikörper) visualized by fluorescence resonance energy transfer (FRET).

  8. Results suggest that PEX3 plays a selective, essential, and direct role in class I peroxisomal membrane protein import as a docking factor for PEX19 (zeige PEX19 Antikörper).

  9. either one or two tryptophan residues of Pex3p (Trp (zeige TBPL1 Antikörper)-104 and Trp (zeige TBPL1 Antikörper)-224) are directly involved in binding to Pex19p.

  10. The cytosolic domain of PEX3, a protein involved in the biogenesis of peroxisomes, binds membrane lipids.

PEX3 Antigen-Profil

Protein Überblick

The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).

Genbezeichner und Symbole assoziert mit PEX3

  • peroxisomal biogenesis factor 3 (LOC692959) Antikörper
  • peroxisomal biogenesis factor 3 (CpipJ_CPIJ013204) Antikörper
  • peroxin 3 (pex3) Antikörper
  • peroxisomal biogenesis factor 3 (LOC100230879) Antikörper
  • peroxisomal biogenesis factor 3 (PEX3) Antikörper
  • peroxisomal biogenesis factor 3 (pex3) Antikörper
  • peroxisomal biogenesis factor 3 (Pex3) Antikörper
  • peroxisomal biogenesis factor 3-like (LOC100760471) Antikörper
  • 1700014F15Rik Antikörper
  • 2810027F19Rik Antikörper
  • 2900010N04Rik Antikörper
  • DDBDRAFT_0204086 Antikörper
  • DDBDRAFT_0238047 Antikörper
  • DDB_0204086 Antikörper
  • DDB_0238047 Antikörper
  • PBD10A Antikörper
  • Peroxin-3 Antikörper
  • TRG18 Antikörper
  • zgc:56313 Antikörper

Bezeichner auf Proteinebene für PEX3

peroxisomal biogenesis factor 3 , transmembrane protein , peroxin-3 , peroxisomal assembly protein PEX3 , transformation-related protein 18 , Peroxisomal assembly protein PEX3 , peroxisomal assembly protein 3 , Peroxisomal biogenesis factor 3

GENE ID SPEZIES
692959 Bombyx mori
6046074 Culex quinquefasciatus
8622947 Dictyostelium discoideum AX4
100230879 Taeniopygia guttata
100582200 Nomascus leucogenys
393197 Danio rerio
444067 Xenopus laevis
421669 Gallus gallus
8504 Homo sapiens
484015 Canis lupus familiaris
515730 Bos taurus
56535 Mus musculus
83519 Rattus norvegicus
100760471 Cricetulus griseus
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