anti-Peripheral Myelin Protein 22 (PMP22) Antikörper

PMP22 encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Zusätzlich bieten wir Ihnen PMP22 Kits (30) und PMP22 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PMP22 5376 Q01453
PMP22 24660 P25094
PMP22 18858 P16646
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Top anti-PMP22 Antikörper auf antikoerper-online.de

Showing 10 out of 96 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PMP22 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IP, IHC, WB Immunohistochemical analysis of GAS3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the an Western blot analysis of GAS3 expression in THP1 (A), MDAMB435 (B), mouse brain (C), mouse liver (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of PMP22 Antibody  in Human normal Uterus cell line lysates (35ug/lane). This demonstrates the PMP22 antibody detected the PMP22 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IHC (p), IHC, WB Staining of PMP22 (brown) in dorsal root ganglion and spinal roots in 20 week fetal spinal cord preparation from rhesus monkey. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from MDA-MB-435 cells, using PMP22 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PMP22 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$467.50
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-PMP22 Polyclonal Antibody, Unconjugated (ABIN726680) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat spinal cord labeled with Anti-PMP22 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert IHC (p), WB <b>Immunohistochemistry </b>analyzes of GAS3 antibody in paraffin-embedded human brain tissue. <b>Western blot </b>analysis of GAS3 antibody in extracts from MDA-MB-435 cells. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$490.19
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

PMP22 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PMP22 Antikörper

  1. Monoclonal PMP22 Primary Antibody für IHC (p) - ABIN534026 : Gregson, Zhang, Pritchard, Wang, Sanvito, Hayday, Hughes: Characterization of a monoclonal antibody specific for human peripheral myelin protein 22 and its use in immunohistochemical studies of the fetal and adult nervous system. in Journal of the peripheral nervous system : JPNS 2007 (PubMed)

Weitere Antikörper gegen PMP22 Interaktionspartner

Zebrafish Peripheral Myelin Protein 22 (PMP22) Interaktionspartner

  1. The results of this study indicated that an adequate pmp22 transcription level is necessary for correct myelination of jawed vertebrates.

Human Peripheral Myelin Protein 22 (PMP22) Interaktionspartner

  1. Exome sequencing identified MFN2 (zeige MFN2 Antikörper) SNVs in two of the individuals. Neuropathy-associated CNV outside of the PMP22 locus is rare in Charcot-Marie-Tooth (CMT) disease . Nevertheless, there is potential clinical utility in testing for CNVs and exome sequencing in CMT cases negative for the CMT1A duplication.

  2. We discovered that Tead1 (zeige TEAD1 Antikörper) and co-activators Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) are required for Pmp22 expression, as well as for the expression of Egr2 (zeige EGR2 Antikörper) Tead1 (zeige TEAD1 Antikörper) directly binds Pmp22 and Egr2 (zeige EGR2 Antikörper) enhancers early in development and Tead1 (zeige TEAD1 Antikörper) binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 (zeige TEAD1 Antikörper) as a novel regulator of Pmp22 expression during development in concert with Sox10 (zeige SOX10 Antikörper) and Egr2 (zeige EGR2 Antikörper)

  3. This study demonstrated We show that blink (zeige TGFb Antikörper) reflex studies are reliable for identification of inherited demyelinating polyneuropathy (with pmp22 mutation) regardless of severity and can facilitate algorithmic decisions in genetic testing.

  4. Findings suggest that miR (zeige MLXIP Antikörper)-200bc/429 inhibit OS cells proliferation and invasion by targeting PMP22, and function as a tumor suppressor.

  5. PMP22 deletion leads to functional, metabolic and macro-structural alterations in the afferent visual system of hereditary neuropathy with liability to pressure palsies patients.

  6. we report molecular and clinical characterizations of six subjects with the reciprocal phenomenon of deletions spanning both genes, i.e., PMP22-RAI1 (zeige DOM3Z Antikörper) deletions. Systematic clinical studies revealed features consistent with SMS (zeige SMS Antikörper), including features of intellectual disability, speech and gross motor delays, behavioral problems and ocular abnormalities.

  7. Data suggest that the father has carried the same duplication of the peripheral myelin protein 22 (PMP22) gene but with no detectable symptom may be due to irregular transmission pattern of the mutation.

  8. our data suggest that an alteration of mRNA processing could be a pathogenic mechanism in CMT1A.

  9. Data (including data from studies using recombinant proteins that lack typical in-vivo post-translational modifications such as palmitoylation) suggest PMP22 exhibits little tendency to partition into liquid-ordered domains of unilamellar vesicles.

  10. PMP22 gene knockdown inhibited progression of Chronic Myeloid Leukemia (zeige BCL11A Antikörper).

Mouse (Murine) Peripheral Myelin Protein 22 (PMP22) Interaktionspartner

  1. We discovered that Tead1 (zeige TEAD1 Antikörper) and co-activators Yap (zeige YAP1 Antikörper) and Taz (zeige TAZ Antikörper) are required for Pmp22 expression, as well as for the expression of Egr2 (zeige EGR2 Antikörper) Tead1 (zeige TEAD1 Antikörper) directly binds Pmp22 and Egr2 (zeige EGR2 Antikörper) enhancers early in development and Tead1 (zeige TEAD1 Antikörper) binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 (zeige TEAD1 Antikörper) as a novel regulator of Pmp22 expression during development in concert with Sox10 (zeige SOX10 Antikörper) and Egr2 (zeige EGR2 Antikörper)

  2. The basal lamina and PMP22 act in concert to contribute to a resilience and integrity of peripheral nerves at the single fibre level.

  3. A role was identified for PMP22 in the linkage of the actin cytoskeleton with the plasma membrane.

  4. This study demonistrated that Paranodal dysmyelination in peripheral nerves of Trembler mice.

  5. This study showed that a number of ongoing pathogenic mechanisms contribute to the progression of the neuropathy in C22 mice, which initiates with abnormal expression of PMP22.

  6. Pxmp2 in the mammary fat pad is plays a critical role in stromal lipid homeostasis and in development of mammary gland epithelium in mice

  7. This study revealed a novel mechanism by which PMP22 deficiency affects nerve conduction not through removal of myelin, but through disruption of myelin junctions

  8. This study showed that mouse PMP22 is palmitoylated at C85 and mutating C85S abolishes PMP22 palmitoylation.

  9. Peripheral myelin protein 22 (PMP22) performs distinct actions on the formation, maturation, degeneration and regeneration of sciatic nerve myelin sheath.

  10. Egr2 (zeige EGR2 Antikörper) and Sox10 (zeige SOX10 Antikörper) activity are directly involved in mediating the developmental induction of Pmp22 expression through an intronic enhancer.

PMP22 Antigen-Profil

Protein Überblick

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein.

Genbezeichner und Symbole assoziert mit PMP22

  • peripheral myelin protein 22a (pmp22a) Antikörper
  • peripheral myelin protein 22 (PMP22) Antikörper
  • peripheral myelin protein 22 S homeolog (pmp22.S) Antikörper
  • peripheral myelin protein 22 (pmp22) Antikörper
  • peripheral myelin protein 22 (Pmp22) Antikörper
  • peroxisomal membrane protein 2 (Pxmp2) Antikörper
  • 22kDa Antikörper
  • CMT1A Antikörper
  • CMT1E Antikörper
  • DSS Antikörper
  • Gas-3 Antikörper
  • HMSNIA Antikörper
  • HNPP Antikörper
  • MGC69407 Antikörper
  • MGC80653 Antikörper
  • PMP22 Antikörper
  • Sp110 Antikörper
  • Tr Antikörper
  • trembler Antikörper
  • wu:fa04d03 Antikörper
  • wu:fa08d03 Antikörper

Bezeichner auf Proteinebene für PMP22

peripheral myelin protein 22 , growth arrest-specific protein 3 , PMP-22 , SAG , SR13 myelin protein , schwann cell membrane glycoprotein , peripheral myelin protein, 22 kDa , PAS positive glycoprotein , PASII , 22 kDa peroxisomal membrane protein , peroxisomal membrane protein 2, 22 kDa

GENE ID SPEZIES
334817 Danio rerio
417327 Gallus gallus
446837 Xenopus laevis
479509 Canis lupus familiaris
594946 Xenopus (Silurana) tropicalis
100302348 Ovis aries
5376 Homo sapiens
24660 Rattus norvegicus
18858 Mus musculus
534497 Bos taurus
100034146 Equus caballus
693527 Macaca mulatta
744977 Pan troglodytes
100172535 Pongo abelii
19301 Mus musculus
Ausgewählte Anbieter für anti-PMP22 (PMP22) Antikörper
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