anti-Perilipin 1 (PLIN1) Antikörper

The protein encoded by PLIN1 coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. Zusätzlich bieten wir Ihnen PLIN1 Kits (31) und PLIN1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PLIN1 5346 O60240
PLIN1 25629 P43884
PLIN1 103968 Q8CGN5
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Top anti-PLIN1 Antikörper auf antikoerper-online.de

Showing 10 out of 121 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PLIN Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-PLIN <br /> Antibody Titration: 1.25 µg/mL <br /> Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN190817 (0.01µg/ml) staining of Human Adipose lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN190817 staining of differentiated 3T3-L1 adipocytes. Data kindly provided by Prof. J. Granneman, Detroit, USA 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Ziege Unkonjugiert ELISA, WB ABIN190818 (0.01µg/ml) staining of Human Adipose lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Detection of Perilipin in human liver samples using ABIN258311 (2ug/ml). Western Blot: Perilipin Antibody [ABIN2583110] - Total protein from Human breast (lane 1), Human adipose membrane fraction (lane 2) and Human adipose tissue (lane 3) were separated on a 12% gel by SDS-PAGE. Protein was transferred to PVDF membrane, probed with 2 ug/ml anti-perilipin antibody followed by anti-rabbit HRP conjugated secondary antibody and detected with chemiluminescence. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Ziege Unkonjugiert ELISA, ICC, IF, IHC, IHC (fro), IHC (p), WB Western Blot: Perilipin (C Terminus) Antibody [ABIN253096] - ABIN253096(0.01ug/ml) staining of Human Adipose lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN253096 staining of differentiated 3T3-L1 adipocytes. Data kindly provided by Prof. J. Granneman, Detroit, USA 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Kaninchen Unkonjugiert WB 200 μg Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Rind (Kuh) Meerschweinchen Unkonjugiert IHC (fro), IHC (p), WB   0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$489.50
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB   100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Ziege Unkonjugiert IHC (p), ELISA, WB Human Colon (formalin-fixed, paraffin-embedded) stained with PLIN antibody ABIN364425 at 2 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Rind (Kuh) Ziege Unkonjugiert IHC (p), ELISA, WB Human Colon (formalin-fixed, paraffin-embedded) stained with PLIN antibody ABIN364426 at 4 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details

PLIN1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-PLIN1 Antikörper

  1. Human Polyclonal PLIN1 Primary Antibody für ELISA, ICC - ABIN253096 : Rigamonti, Brennand, Lau, Cowan: Rapid cellular turnover in adipose tissue. in PLoS ONE 2011 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal PLIN1 Primary Antibody für ICC, IF - ABIN258311 : Kadereit, Kumar, Wang, Miranda, Snapp, Severina, Torregroza, Evans, Silver: Evolutionarily conserved gene family important for fat storage. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal PLIN1 Primary Antibody für ELISA, WB - ABIN4344849 : Famulla, Schlich, Sell, Eckel: Differentiation of human adipocytes at physiological oxygen levels results in increased adiponectin secretion and isoproterenol-stimulated lipolysis. in Adipocyte 2013 (PubMed)
    Show all 2 Pubmed References

  4. Cow (Bovine) Polyclonal PLIN1 Primary Antibody für IHC (fro), IHC (p) - ABIN113463 : Heid, Moll, Schwetlick, Rackwitz, Keenan: Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. in Cell and tissue research 1998 (PubMed)
    Show all 6 Pubmed References

  5. Human Polyclonal PLIN1 Primary Antibody für IF (p), IHC (p) - ABIN704141 : Stelmanska, Szrok, Swierczynski et al.: Progesterone-induced down-regulation of hormone sensitive lipase (Lipe) and up-regulation of G0/G1 switch 2 (G0s2) genes expression in inguinal adipose tissue of female rats is reflected by ... in The Journal of steroid biochemistry and molecular biology 2015 (PubMed)

Weitere Antikörper gegen PLIN1 Interaktionspartner

Human Perilipin 1 (PLIN1) Interaktionspartner

  1. The PLIN 6 polymorphism of the perilipin gene may influence the risk of obesity during adolescence.

  2. Variability at the PLIN1 locus is associated with variability in weight loss. Moreover, eating late is related to lower weight-loss effectiveness among carriers of the AA genotype at the PLIN1 14995A>T variant.

  3. The strong association of PLIN1, CFD (zeige CFD Antikörper) and ADIPOQ (zeige ADIPOQ Antikörper) genes with adipogenesis prompted authors to study the influence the bone health status as evaluated by quantitative ultrasound (QUS) bone densitometer in a North Indian cohort. Overall, ADIPOQ (zeige ADIPOQ Antikörper) (rs1501299 and rs3774261) and combined cluster of PLIN1 rs2304796 and rs2304795) and CFD (zeige CFD Antikörper) (rs1683563) demonstrated correlation.

  4. Perilipin 1 expression increased with adipocytic differentiation of liposarcoma subtypes showing statistical significance.

  5. Based on the PCR with mismatched primers PLIN1 polymorphisms could be identified effectively in Chinese Han population.

  6. Conserved amphipathic helices mediate lipid droplet targeting of PLIN1, PLIN2 (zeige PLIN2 Antikörper), and PLIN3 (zeige PLIN3 Antikörper).

  7. Skeletal muscle PLIN proteins likely play a role in the hydrolysis of triglycerides stored in lipid droplets and the passage of fatty acids to the mitochondria for oxidation.

  8. The functional PLIN1 rs6496589 may influence the risk of central obesity through possible regulation of lipid storage.

  9. After bariatric surgery-induced weight loss, PLIN1 gene/protein expression in SAT increased significantly. Findings suggest a positive functional interaction between PLIN1 & mitochondrial biogenesis-related genes in human adipose tissue.

  10. Use of molecular docking software to design perilipin-1 inhibitors as antiobesity agents.

Cow (Bovine) Perilipin 1 (PLIN1) Interaktionspartner

  1. Perilipin, which was thought to be characteristic for lipid droplets of adipocytes and steroidogenic cells, becomes de novo expressed in hepatocytes of human, mouse, and cattle liver.

Mouse (Murine) Perilipin 1 (PLIN1) Interaktionspartner

  1. ex vivo studies in human primary adipocytes, demonstrate that perilipin 1 binds to AQP7 (zeige AQP7 Antikörper), and that catecholamine activated protein kinase A phosphorylates the N-terminus of AQP7 (zeige AQP7 Antikörper), thereby reducing complex formation

  2. Here, we identify synthetic ligands that release ABHD5 (zeige ABHD5 Antikörper) from PLIN1 or PLIN5 (zeige PLIN5 Antikörper) without PKA activation and rapidly activate adipocyte and muscle lipolysis.

  3. Heterozygous Plin1+/- SVCs were able to develop lipid droplets, with both the number and size more than in Plin1-/- SVCs but less than in Plin1+/+ SVCs, indicating that Plin1 haploinsufficiency accounts for attenuated adipogenesis.

  4. Plin1 deficiency in bone marrow-derived cells may be responsible for reduced atherosclerotic lesions in the mice

  5. Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion.

  6. Data suggest cardiotrophin-1 (zeige CTF1 Antikörper) up-regulates lipolysis in adipocytes via 1) induction of Plin1, 2) activation of hormone sensitive lipase (zeige LIPE Antikörper) (via phosphorylation by PKA), and 3) inactivation of adipose triglyceride lipase (zeige PNPLA2 Antikörper) (via up-regulation of G0S2 (zeige G0S2 Antikörper)).

  7. Adipocytes of Plin1/ mice showed robust basal lipolysis and fatty acid efflux to the plasma. Such adipose tissue dysfunctions accounted for the ectopic lipid accumulation and enhanced fatty acid transport and oxidation in Plin1/ hearts.

  8. QRFP-43 attenuates lipolysis by preventing the formation of an active complex between perilipin A, caveolin-1 (zeige CAV1 Antikörper), the catalytic subunit of protein kinase (zeige CDK7 Antikörper) and hormone-sensitive lipase (zeige LIPE Antikörper) on lipid droplets.

  9. ESR1 (zeige ESR1 Antikörper) regulates ATGL (zeige PNPLA2 Antikörper) and perilipin-mediated lipid metabolism and droplet size in femurs from mice.

  10. Collectively these data suggest that whereas perilipin 1 potently suppresses basal lipolysis in adipocytes, perilipins 2 and 3 facilitate higher rates of basal lipolysis

Pig (Porcine) Perilipin 1 (PLIN1) Interaktionspartner

  1. PLIN1 and PLIN2 (zeige PLIN2 Antikörper) have been evaluated as candidate genes for growth, carcass and meat quality traits in pigs; two single-nucleotide polymorphisms, one in intron 2 of the PLIN1 gene (JN860199:g.173G>A) and the 3' untranslated region of the PLIN2 (zeige PLIN2 Antikörper) gene (GU461317:g.98G>A); results obtained indicate that the PLIN2 (zeige PLIN2 Antikörper) polymorphism could be a useful marker for lean growth.

  2. In pig muscle PLIN1 and PLIN2 (zeige PLIN2 Antikörper) proteins are localized in correspondence with extra and intra-myocellular lipids, respectively.

  3. This work describes the cloning and sequencing of porcine PLIN and M6PRBP1 (zeige PLIN3 Antikörper) cDNAs, the chromosome mapping of these two genes, as well as the expression pattern of porcine PAT genes.

PLIN1 Antigen-Profil

Protein Überblick

The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Perilipin 1 (PLIN1) Antikörper

  • perilipin 1 (PLIN1) Antikörper
  • perilipin 1 (Plin1) Antikörper
  • perilipin 1 (plin1) Antikörper
  • perilipin (LOC692833) Antikörper
  • perilipin 1 L homeolog (plin1.L) Antikörper
  • 6030432J05Rik Antikörper
  • FPLD4 Antikörper
  • LOC692833 Antikörper
  • peri Antikörper
  • PERIA Antikörper
  • perilipin Antikörper
  • plin Antikörper

Bezeichner auf Proteinebene für anti-Perilipin 1 (PLIN1) Antikörper

lipid droplet-associated protein , perilipin-1 , PERI , perilipin A , perilipin B , adipocyte lipid droplet binding protein , perilipin , perilipin 1 , perilipin-1-like

GENE ID SPEZIES
5346 Homo sapiens
25629 Rattus norvegicus
103968 Mus musculus
415487 Gallus gallus
467755 Pan troglodytes
520598 Bos taurus
594876 Xenopus (Silurana) tropicalis
654411 Sus scrofa
692833 Bombyx mori
100036810 Xenopus laevis
100135431 Ovis aries
100407311 Callithrix jacchus
100437952 Pongo abelii
100856637 Canis lupus familiaris
100728074 Cavia porcellus
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