anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antikörper

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. Zusätzlich bieten wir Ihnen Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Proteine (21) und Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PIN1 241593  
PIN1 5300 Q13526
PIN1 298696  
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Top anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antikörper auf antikoerper-online.de

Showing 10 out of 219 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of PIN1 Antibody (Center) (ABIN652906) in HL-60 cell line lysates (35 µg/lane). PIN1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PIN1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with insulin 0.01U/ml 15', using Pin1 (Phospho-Ser16) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart, using Pin1 (Phospho-Ser16) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of NIH-3T3 cells, using Pin1 (Ab-1619) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Rind (Kuh) Kaninchen Unkonjugiert EIA, WB 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
495,00 €
Details
Ratte Ziege Unkonjugiert ELISA, WB ABIN185726 (0.2µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Huhn Unkonjugiert ICC, IF, WB Immunocytochemistry/Immunofluorescence: Pin1 Antibody [NBP1-05424] - HeLa cells stained with NBP1-05424 antibody to Pin-1 (1:1000 dilution, green) and monoclonal to fibrillarin, ABIN438364 (red). Pin-1 stains the nuclear matrix and, much more faintly, the cytoplasm. The fibrillarin antibody marks nucleoli. Western Blot: Pin1 Antibody [NBP1-05424] - Western blot of whole HeLa cell homogenate stained with NBP1-05424, at dilution of 1:10000. A prominent band running with an apparent SDS-PAGE molecular weight of approx. 21kDa corresponds to Pin1. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
291,00 €
Details
Ratte Ziege Unkonjugiert ELISA, WB ABIN251689 (0.2?g/ml) staining of Rat Brain lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Human Maus Unkonjugiert WB PIN1 Antibody (ABIN1882275) western blot analysis in Hela,293,mouse NIH/3T3,PC-12,COS-7 cell line and mouse brain,rat brain tissue lysates (35 µg/lane). This demonstrates the PIN1 antibody detected the PIN1 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB Anti- PIN1 Picoband antibody, Western blotting All lanes: Anti PIN1  at 0.5ug/ml Lane 1: Rat Lung Tissue Lysate at 50ug Lane 2: Mouse Lung Tissue Lysate at 50ug Lane 3: NRK Whole Cell Lysate at 40ug Lane 4: A549 Whole Cell Lysate at 40ug Lane 5: 293T Whole Cell Lysate at 40ug Lane 6: MCF-7 Whole Cell Lysate at 40ug Predicted bind size: 19KD Observed bind size: 19KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti Phospho-Pin1 (Ser16) Polyclonal Antibody, Unconjugated (ABIN745073) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
326,42 €
Details

PIN1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antikörper

  1. Cow (Bovine) Polyclonal PIN1 Primary Antibody für EIA, WB - ABIN401395 : Esnault, Shen, Whitesel, Malter: The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Zeige alle 2 Referenzen für 401395

  2. Human Polyclonal PIN1 Primary Antibody für ICC, IF - ABIN438364 : Islam, Bae, Yoon, Woo, Baek, Kim, Uchida, Ryoo: Pin1 regulates osteoclast fusion through suppression of the master regulator of cell fusion DC-STAMP. in Journal of cellular physiology 2014 (PubMed)
    Zeige alle 2 Referenzen für 438364

  3. Human Polyclonal PIN1 Primary Antibody für IF, ELISA - ABIN1532476 : Lu, Hanes, Hunter: A human peptidyl-prolyl isomerase essential for regulation of mitosis. in Nature 1996 (PubMed)
    Zeige alle 2 Referenzen für 1532476

  4. Rat (Rattus) Polyclonal PIN1 Primary Antibody für ELISA, WB - ABIN251689 : Pastorino, Sun, Lu, Zhou, Balastik, Finn, Wulf, Lim, Li, Li, Xia, Nicholson, Lu: The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. in Nature 2006 (PubMed)

  5. Human Monoclonal PIN1 Primary Antibody für WB - ABIN1882275 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)

Weitere Antikörper gegen Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Interaktionspartner

Mouse (Murine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Pin1 plays important role in the cell cycle progression and increase oval cells proliferation which may be crucial in chronic liver injury.

  2. in vivo functional analyses of Pin1 in the GFAP (zeige GFAP Antikörper)-tTA;TRE (zeige TREH Antikörper)-SmoA1 mouse model of Hedgehog (zeige SHH Antikörper)-driven medulloblastoma demonstrate that the loss of Pin1 impairs tumor development and dramatically increases survival.

  3. Data, including data from studies conducted with knockout mice, suggest that Pin1 (prolyl isomerase 1) expression in pancreatic beta-cells is markedly elevated in obesity from diet high in fat/sucrose; Pin1 appears to be involved in proliferation of beta-cells and in regulation of secretion of insulin (zeige INS Antikörper); Pin1 interacts with Sik2 (salt-inducible kinase 2 (zeige SIK2 Antikörper)) to regulate calcium signaling.

  4. Pin1 knockout in lupus-prone MRL lpr mi (zeige TLR7 Antikörper)ce pre (zeige TLR9 Antikörper)vents expres (zeige IRAK1 Antikörper)sion o (zeige IRF7 Antikörper)f lupus phenotype.

  5. By interacting with PSD-95 (zeige DLG4 Antikörper), Pin1 dampens PSD-95 (zeige DLG4 Antikörper) ability to complex with NMDARs, thus negatively affecting NMDAR (zeige GRIN1 Antikörper) signaling and spine morphology.

  6. Oral administration of brown algae polyphenol, a Pin1 inhibitor, reduced fat buildup in mice.

  7. The findings provide evidence for a putative novel role of PIN1 in the development of the nociceptive system and indicate phosphorylation-mediated conformational changes as a mechanism for regulating the PRRXL1 (zeige DRGX Antikörper) role in the process.

  8. Data show that peptidyl-prolyl isomerase (Pin1) inhibition inhibits high glucose (HG)-induced cardiac fibroblasts (CFs) proliferation and migration.

  9. Pin1 knock-out mice exhibited disturbed neuronal projections from the cerebral cortex and reduced white matter tracks.

  10. Pin1 plays a vital role on the development of vascular inflammation and atherosclerosis in ApoE (zeige APOE Antikörper)-/- mice.

Xenopus laevis Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Pin1 is an essential factor regulating CPEB degradation

  2. Pin1 binding is required for the inactivation of XeWee1B at M phase, presumably causing isomerization of the phospho-TP motif and thereby impairing the function of the Wee (zeige WEE1 Antikörper)-box

Human Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. in in silico gene expression analysis of human T-ALL samples we observed a significant correlation between Pin1 and Notch3 (zeige NOTCH3 Antikörper) expression levels, which may further suggest a key role of the newly identified Notch3 (zeige NOTCH3 Antikörper)-Pin1 axis in T-cell Acute Lymphoblastic Leukemia (T-ALL) aggressiveness and progression. Thus, combined suppression of Pin1 and Notch3 (zeige NOTCH3 Antikörper) proteins may be exploited as an additional target therapy for T-ALL

  2. The study demonstrates the oncogenic role of PIN1 in NPC (zeige NPC1 Antikörper) tumorigenesis, and shows that its overexpression can enhance tumor cell growth via the upregulation of cyclinD1.

  3. Pin1 expression was decreased remarkably in temporal lobe epilepsy patients compared to controls.

  4. Data, including data from studies conducted with knockout mice, suggest that PIN1 (prolyl isomerase 1) expression in pancreatic beta-cells is markedly elevated in obesity from diet high in fat/sucrose; PIN1 appears to be involved in proliferation of beta-cells and in regulation of secretion of insulin (zeige INS Antikörper); PIN1 interacts with Sik2 (salt-inducible kinase 2 (zeige SIK2 Antikörper)) to regulate calcium signaling.

  5. Knockdown of PIN1 potently blocks TLR-7 (zeige TLR7 Antikörper)/TLR-9 (zeige TLR9 Antikörper)/Pin1/IRAK-1 (zeige IRAK1 Antikörper)/IRF-7 (zeige IRF7 Antikörper) signaling in vitro.

  6. Data indicate the complexity of interactions between Pin1 and activated IRAK1 (zeige IRAK1 Antikörper), suggesting that phosphorylation of neighboring Ser (zeige SIGLEC1 Antikörper)/Thr (zeige TRH Antikörper)-Pro motifs in proteins might provide competitive advantage at cellular concentrations for engaging with Pin1.

  7. Surprisingly, the authors discover that Pin1 does not promote phosphorylated tau-induced microtubule formation in vitro, refuting the commonly accepted model in which Pin1 binding and catalysis on the A180 epitope restores the function of the Alzheimer's associated phosphorylated tau in tubulin (zeige TUBB Antikörper) assembly.

  8. Importantly, site-specific measurements of Pin1-catalysis of CDK2 (zeige CDK2 Antikörper)/CycA (zeige CCNA2 Antikörper)-phosphorylated full-length tau reveal a number of sites that are catalyzed simultaneously with different efficiencies.

  9. Results show that Pin1 plays a dual role, both positive and negative, in regulating NO production and in mediating the pathogenesis of cardiovascular diseases. Pin1 functions may vary a lot under different circumstances.

  10. reciprocal regulation of Pin1 and XBP1s is associated with the activation of oncogenic pathways, and the relationship of PIN1 and XBP1 (zeige XBP1 Antikörper) may be an attractive target for novel therapy in cancers

Cow (Bovine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. The data provide the first evidence that Pin 1 expression in the granulosa cells but not the theca cells changes during follicular development, and that FSH (zeige BRD2 Antikörper) stimulate the expression of the Pin 1 gene.

Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antigen-Profil

Protein Überblick

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit PIN1

  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, retrogene 1 (Pin1rt1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1-b) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1-a) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1) Antikörper
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (ppiD) Antikörper
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PITG_11123) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (Pin1) Antikörper
  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1) Antikörper
  • 0610025L01Rik Antikörper
  • D9Bwg1161e Antikörper
  • DOD Antikörper
  • OTTMUSG00000014964 Antikörper
  • pin1 Antikörper
  • Pin1-ps1 Antikörper
  • pin1a Antikörper
  • pin1b Antikörper
  • Pin1l Antikörper
  • UBL5 Antikörper

Bezeichner auf Proteinebene für PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1, pseudogene 1 , prolyl isomerase Pin1 b , prolyl isomerase Pin1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 b , protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 a , peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 , PPIase Pin1 , protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 , rotamase Pin1 , peptidyl-prolyl cis-trans isomerase Pin1

GENE ID SPEZIES
241593 Mus musculus
399385 Xenopus laevis
493472 Xenopus (Silurana) tropicalis
503670 Xenopus laevis
711095 Macaca mulatta
745021 Pan troglodytes
5807350 Sorangium cellulosum So ce56
9476290 Phytophthora infestans T30-4
5300 Homo sapiens
484963 Canis lupus familiaris
298696 Rattus norvegicus
535470 Bos taurus
100512827 Sus scrofa
23988 Mus musculus
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