anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antikörper

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. Zusätzlich bieten wir Ihnen Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Proteine (19) und Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PIN1 241593  
PIN1 5300 Q13526
PIN1 298696  
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Top anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antikörper auf antikoerper-online.de

Showing 10 out of 216 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with insulin 0.01U/ml 15', using Pin1 (Phospho-Ser16) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart, using Pin1 (Phospho-Ser16) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of NIH-3T3 cells, using Pin1 (Ab-1619) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of PIN1 Antibody (Center) (ABIN652906) in HL-60 cell line lysates (35 µg/lane). PIN1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PIN1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB Anti- PIN1 Picoband antibody, Western blotting All lanes: Anti PIN1  at 0.5ug/ml Lane 1: Rat Lung Tissue Lysate at 50ug Lane 2: Mouse Lung Tissue Lysate at 50ug Lane 3: NRK Whole Cell Lysate at 40ug Lane 4: A549 Whole Cell Lysate at 40ug Lane 5: 293T Whole Cell Lysate at 40ug Lane 6: MCF-7 Whole Cell Lysate at 40ug Predicted bind size: 19KD Observed bind size: 19KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Rind (Kuh) Kaninchen Unkonjugiert EIA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$419.10
Details
Ratte Ziege Unkonjugiert ELISA, WB ABIN185726 (0.2µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Maus Unkonjugiert WB PIN1 Antibody (ABIN1882275) western blot analysis in Hela,293,mouse NIH/3T3,PC-12,COS-7 cell line and mouse brain,rat brain tissue lysates (35 µg/lane). This demonstrates the PIN1 antibody detected the PIN1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Huhn Unkonjugiert ICC, IF, WB Immunocytochemistry/Immunofluorescence: Pin1 Antibody [NBP1-05424] - HeLa cells stained with NBP1-05424 antibody to Pin-1 (1:1000 dilution, green) and monoclonal to fibrillarin, ABIN438364 (red). Pin-1 stains the nuclear matrix and, much more faintly, the cytoplasm. The fibrillarin antibody marks nucleoli. Western Blot: Pin1 Antibody [NBP1-05424] - Western blot of whole HeLa cell homogenate stained with NBP1-05424, at dilution of 1:10000. A prominent band running with an apparent SDS-PAGE molecular weight of approx. 21kDa corresponds to Pin1. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$381.94
Details
Ratte Ziege Unkonjugiert ELISA, WB ABIN251689 (0.2?g/ml) staining of Rat Brain lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details

PIN1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Antikörper

  1. Human Polyclonal PIN1 Primary Antibody für ICC, IF - ABIN438364 : Islam, Bae, Yoon, Woo, Baek, Kim, Uchida, Ryoo: Pin1 regulates osteoclast fusion through suppression of the master regulator of cell fusion DC-STAMP. in Journal of cellular physiology 2014 (PubMed)
    Show all 2 Pubmed References

  2. Rat (Rattus) Polyclonal PIN1 Primary Antibody für ELISA, WB - ABIN251689 : Pastorino, Sun, Lu, Zhou, Balastik, Finn, Wulf, Lim, Li, Li, Xia, Nicholson, Lu: The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. in Nature 2006 (PubMed)

Weitere Antikörper gegen Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 Interaktionspartner

Mouse (Murine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Pin1 silencing in lymphomas retarded disease progression in mice, making Pin1 an attractive therapeutic target in Myc (zeige MYC Antikörper)-driven tumors.

  2. Pin1 enhances adipocyte differentiation by regulating the function of PPARgamma (zeige PPARG Antikörper).

  3. Pin1 serves as a positive regulatory molecule of proplatelet formation of megakaryocytes by enhancing the function of phosphorylated tau.

  4. Direct delivery of recombinant Pin1 via fibroin nanoparticle encapsulated cationic lipid complex successfully rescued osteoblast differentiation of pin-1 deficient cells.

  5. Pin1 plays important role in the cell cycle progression and increase oval cells proliferation which may be crucial in chronic liver injury.

  6. in vivo functional analyses of Pin1 in the GFAP (zeige GFAP Antikörper)-tTA;TRE (zeige TREH Antikörper)-SmoA1 mouse model of Hedgehog (zeige SHH Antikörper)-driven medulloblastoma demonstrate that the loss of Pin1 impairs tumor development and dramatically increases survival.

  7. Data, including data from studies conducted with knockout mice, suggest that Pin1 (prolyl isomerase 1) expression in pancreatic beta-cells is markedly elevated in obesity from diet high in fat/sucrose; Pin1 appears to be involved in proliferation of beta-cells and in regulation of secretion of insulin (zeige INS Antikörper); Pin1 interacts with Sik2 (salt-inducible kinase 2 (zeige SIK2 Antikörper)) to regulate calcium signaling.

  8. Pin1 knockout in lupus-prone MRL lpr mi (zeige TLR7 Antikörper)ce pre (zeige TLR9 Antikörper)vents expres (zeige IRAK1 Antikörper)sion o (zeige IRF7 Antikörper)f lupus phenotype.

  9. By interacting with PSD-95 (zeige DLG4 Antikörper), Pin1 dampens PSD-95 (zeige DLG4 Antikörper) ability to complex with NMDARs, thus negatively affecting NMDAR (zeige GRIN1 Antikörper) signaling and spine morphology.

  10. Oral administration of brown algae polyphenol, a Pin1 inhibitor, reduced fat buildup in mice.

Xenopus laevis Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Pin1 is an essential factor regulating CPEB degradation

  2. Pin1 binding is required for the inactivation of XeWee1B at M phase, presumably causing isomerization of the phospho-TP motif and thereby impairing the function of the Wee (zeige WEE1 Antikörper)-box

Human Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. Parallel folding pathways of PIN1 Fip35 WW domain (zeige DRP2 Antikörper) have been explained by infrared spectra and their computer simulations.

  2. High PIN1 expression is associated with stomach neoplasms.

  3. Pin1 is a novel regulator of ATF1 (zeige AFT1 Antikörper) at Thr184.

  4. The dynamic basis for signal propagation in Pin1 N-terminal binding domain WW has been described.

  5. The endoplasmic reticulum (ER) stress decreased Pin1 expression through p53 (zeige TP53 Antikörper) activation, and this mechanism may be associated with ER stress-induced cell death. These data reported here support the importance of Pin1 as a potential target molecule mediating tumor development.

  6. our data suggested that miR (zeige MLXIP Antikörper)-874-3p plays a tumour suppressive role in HCC (zeige FAM126A Antikörper) through down-regulation of PIN1.

  7. in in silico gene expression analysis of human T-ALL samples we observed a significant correlation between Pin1 and Notch3 (zeige NOTCH3 Antikörper) expression levels, which may further suggest a key role of the newly identified Notch3 (zeige NOTCH3 Antikörper)-Pin1 axis in T-cell Acute Lymphoblastic Leukemia (T-ALL) aggressiveness and progression. Thus, combined suppression of Pin1 and Notch3 (zeige NOTCH3 Antikörper) proteins may be exploited as an additional target therapy for T-ALL

  8. The study demonstrates the oncogenic role of PIN1 in NPC (zeige NPC1 Antikörper) tumorigenesis, and shows that its overexpression can enhance tumor cell growth via the upregulation of cyclinD1.

  9. Pin1 expression was decreased remarkably in temporal lobe epilepsy patients compared to controls.

  10. Data, including data from studies conducted with knockout mice, suggest that PIN1 (prolyl isomerase 1) expression in pancreatic beta-cells is markedly elevated in obesity from diet high in fat/sucrose; PIN1 appears to be involved in proliferation of beta-cells and in regulation of secretion of insulin (zeige INS Antikörper); PIN1 interacts with Sik2 (salt-inducible kinase 2 (zeige SIK2 Antikörper)) to regulate calcium signaling.

Cow (Bovine) Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Interaktionspartner

  1. The data provide the first evidence that Pin 1 expression in the granulosa cells but not the theca cells changes during follicular development, and that FSH (zeige BRD2 Antikörper) stimulate the expression of the Pin 1 gene.

Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1) Antigen-Profil

Protein Überblick

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit PIN1

  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, retrogene 1 (Pin1rt1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog (pin1.L) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog (pin1.S) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1) Antikörper
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (ppiD) Antikörper
  • peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PITG_11123) Antikörper
  • peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (Pin1) Antikörper
  • protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1) Antikörper
  • 0610025L01Rik Antikörper
  • D9Bwg1161e Antikörper
  • DOD Antikörper
  • OTTMUSG00000014964 Antikörper
  • pin1 Antikörper
  • Pin1-ps1 Antikörper
  • pin1a Antikörper
  • pin1b Antikörper
  • Pin1l Antikörper
  • UBL5 Antikörper

Bezeichner auf Proteinebene für PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1, pseudogene 1 , prolyl isomerase Pin1 b , prolyl isomerase Pin1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 b , protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1 , peptidylprolyl cis/trans isomerase, NIMA-interacting 1 a , peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 , PPIase Pin1 , protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 , rotamase Pin1 , peptidyl-prolyl cis-trans isomerase Pin1

GENE ID SPEZIES
241593 Mus musculus
399385 Xenopus laevis
493472 Xenopus (Silurana) tropicalis
503670 Xenopus laevis
711095 Macaca mulatta
745021 Pan troglodytes
5807350 Sorangium cellulosum So ce56
9476290 Phytophthora infestans T30-4
5300 Homo sapiens
484963 Canis lupus familiaris
298696 Rattus norvegicus
535470 Bos taurus
100512827 Sus scrofa
23988 Mus musculus
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